p53
p53 inhibitors target the p53 protein, a tumor suppressor that plays a crucial role in regulating the cell cycle, DNA repair, and apoptosis. While p53 is often mutated or inactivated in cancer cells, its inhibition is sometimes necessary to protect healthy cells from apoptosis during certain treatments. On the other hand, restoring p53 function in tumors can lead to cancer cell apoptosis. Research into p53 inhibitors is complex and significant for both understanding cancer mechanisms and developing new therapies. At CymitQuimica, we provide a selection of high-quality p53 inhibitors and modulators to support your research in cancer biology, apoptosis, and therapeutic development.
Products of "p53"
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BIX-01294
CAS:BIX-01294 is an G9a Histone Methyltransferase inhibitor(IC50 : 1.9 μM).Formula:C28H38N6O2Purity:99.31% - 99.64%Color and Shape:SolidMolecular weight:490.64Ref: TM-T7697
1mg40.00€2mg51.00€5mg85.00€10mg117.00€25mg207.00€50mg350.00€100mg518.00€200mg740.00€1mL*10mM (DMSO)131.00€Anti-p53 Antibody (9G129)
Anti-p53 Antibody (9G129) is a Rabbit antibody targeting p53. Anti-p53 Antibody (9G129) can be used in IHC-P,ICC/IF.Color and Shape:Odour LiquidHLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled
p53 is a tumor suppressor protein.Color and Shape:Odour Lyophilized PowderSCH529074
CAS:SCH529074 is a selective activator of p53 (Ki = 1 μM) and can be used in studies about non-small-cell lung carcinoma.Formula:C31H36Cl2N6Purity:98.71%Color and Shape:SolidMolecular weight:563.56Ref: TM-T37042
1mg35.00€2mg46.00€5mg64.00€10mg104.00€25mg220.00€50mg328.00€100mg469.00€1mL*10mM (DMSO)75.00€Schisandrol B
CAS:Schisandrol B fights neuroinflammation, liver/renal damage, and reduces cell growth via multiple signaling pathways.Formula:C23H28O7Purity:99.14% - 99.32%Color and Shape:SolidMolecular weight:416.46Ref: TM-T6S1917
5mg71.00€10mg96.00€25mg202.00€50mg303.00€100mg452.00€500mg1,035.00€1mL*10mM (DMSO)79.00€CTX1
CAS:CTX1 is a small molecule activator of p53.Formula:C14H10N4Purity:98%Color and Shape:SolidMolecular weight:234.26PDK4-IN-1 hydrochloride
CAS:PDK4-IN-1 hydrochloride is an anthraquinone derivative and a potent and orally active inhibitor of pyruvate dehydrogenase kinase 4 (PDK4, IC50 value = 84 nM).Formula:C22H20ClN3O2Purity:99.54%Color and Shape:SolidMolecular weight:393.87Ref: TM-T12412L
1mg127.00€5mg300.00€10mg457.00€25mg750.00€50mg1,026.00€100mg1,406.00€500mg2,822.00€1mL*10mM (DMSO)329.00€Etoposide
CAS:Etoposide (VP-16-213) is a topoisomerase II inhibitor that inhibits DNA synthesis by forming a complex with topoisomerase II and DNA (IC50=60.3 μM).Formula:C29H32O13Purity:99.19% - 99.94%Color and Shape:Crystals From Methanol SolidMolecular weight:588.56Anti-p53 Antibody (9G324)
Anti-p53 Antibody (9G324) is an antibody targeting p53. Anti-p53 Antibody (9G324) can be used in ELISA, IF.Color and Shape:Odour LiquidAmifostine thiol dihydrochloride
CAS:Amifostine (WR 1065) activates p53 via JNK and shields tissues from cancer drug toxicity.Formula:C5H16Cl2N2SPurity:100%Color and Shape:SolidMolecular weight:207.165BML-259
CAS:BML-259 inhibits CDK5/CDK2 (IC50: 64/98 nM) for cancer and neurodegeneration research.Formula:C14H16N2OSPurity:99.68%Color and Shape:SolidMolecular weight:260.35Ref: TM-T36964
5mg50.00€10mg85.00€25mg169.00€50mg279.00€100mg487.00€500mg1,035.00€1mL*10mM (DMSO)52.00€CT-1
CAS:CT-1 is a DNA minor groove ligand and causes p53-dependent breast cancer cell apoptosis.Formula:C29H23F3N4OPurity:99.24%Color and Shape:SolidMolecular weight:500.51LLY-507
CAS:LLY-507 is an effective, cell-active, and specific inhibitor of protein-lysine Methyltransferase SMYD2.Formula:C36H42N6OPurity:99.56% - 99.93%Color and Shape:SolidMolecular weight:574.76Ref: TM-T6879
1mg44.00€2mg55.00€5mg85.00€10mg138.00€25mg304.00€50mg552.00€100mg787.00€1mL*10mM (DMSO)110.00€HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Monomer Protein, Human, MHC (His & Avi), Biotinylated
p53 is a tumor suppressor protein.Color and Shape:Odour Lyophilized Powder(S)-10-Hydroxycamptothecin
CAS:(S)-10-Hydroxycamptothecin (10-HCPT) is a DNA topoisomerase I inhibitor, utilized as a clinical therapy agent against hepatoma.Formula:C20H16N2O5Purity:99.09% - 99.81%Color and Shape:SolidMolecular weight:364.35HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Monomer Protein, Human, MHC (His & Avi)
p53 is a tumor suppressor protein.Color and Shape:Odour Lyophilized PowderLeptomycin B
CAS:Leptomycin B: potent CRM1 inhibitor, blocks protein nuclear export and cell cycle, antifungal, modifies cysteine.Formula:C33H48O6Purity:99.04% - 99.71%Color and Shape:White Crystalline SolidMolecular weight:540.73Ref: TM-T15735
1mg202.00€2mg341.00€5mg620.00€10mg882.00€25mg1,320.00€50mg1,776.00€100mg2,403.00€1mL*10mM (DMSO)283.00€SLMP53-1
CAS:SLMP53-1 is a p53 activator with anti-tumor activity, activates reprogramming of glucose metabolism, and interferes with angiogenesis and migrationFormula:C20H18N2O2Purity:99.64%Color and Shape:SolidMolecular weight:318.37Ref: TM-T60839
1mg126.00€5mg298.00€10mg487.00€25mg938.00€50mg1,568.00€100mg2,517.00€1mL*10mM (DMSO)35.00€NSC 66811
CAS:NSC 66811 inhibits MDM2-p53 interaction with 120 nM affinity, activating p53 in cancer cells.Formula:C23H20N2OPurity:96.94%Color and Shape:SolidMolecular weight:340.42NSC 146109 hydrochloride
CAS:NSC 146109 hydrochloride is an activator of p53 targeting MDMX. NSC 146109 hydrochloride can be used for studies on breast cancer.Formula:C17H17ClN2SPurity:97.03%Color and Shape:SolidMolecular weight:316.85
