Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase
- CDK
- Cell Cycle Arrest
- Chk
- c-Myc
- Dynamin
- DYRK
- Ferroptosis
- HSP
- Integrin
- Kinesin
- KSP
- LIM Kinase
- Microtubule Associated
- PKC
- PLK
- Rho
- ROCK
- Wee1
Show 11 more subcategories
Products of "Cell Cycle/Checkpoint"
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DNA Gyrase-IN-9
DNA Gyrase-IN-9 (compound 4j), an antibacterial agent, selectively targets DNA gyrase.Formula:C26H18ClN3O2Purity:98%Color and Shape:SolidMolecular weight:439.89IXA6
CAS:IXA6 is an IRE1/XBP1s agonist with potential vasoprotective activity for the study of neurodegenerative diseases such as Parkinson's disease.Formula:C22H20ClN3O3SPurity:98.63%Color and Shape:SolidMolecular weight:441.93CW-069
CAS:CW-069 (IC50=75 μM), an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity over KSP.Formula:C23H21IN2O3Purity:97.52% - 98.59%Color and Shape:SolidMolecular weight:500.33Ref: TM-T6209
1mg43.00€5mg90.00€10mg125.00€25mg216.00€50mg306.00€100mg432.00€500mg938.00€1mL*10mM (DMSO)89.00€DNA Gyrase-IN-8
CAS:DNA Gyrase-IN-8 is a potent inhibitor of DNA gyrase, demonstrating antimicrobial activity with an IC50 of 8.45 µM [1].Formula:C19H14BrN5OPurity:98%Color and Shape:SolidMolecular weight:408.25Cdc7-IN-7
CAS:Cdc7-IN-7 is a potent inhibitor of Cdc7 kinase.Formula:C21H22N4O5Purity:99.25%Color and Shape:SolidMolecular weight:410.42ZIM
CAS:ZIM, from 4-Aminoantipyrine, induces DNA and chromosomal damage, cell death, and phagocytosis, with potential in cancer therapy.Formula:C20H19N3O3Purity:99.13%Color and Shape:SolidMolecular weight:349.38Ref: TM-T72024
5mg39.00€10mg58.00€25mg105.00€50mg170.00€100mg271.00€200mg398.00€1mL*10mM (DMSO)52.00€Pyrintegrin
CAS:Pyrintegrin: β1-integrin agonist, boosts embryonic stem cell survival, and podocyte protection, improves cell-matrix adhesion.Formula:C23H25N5O3SPurity:97.81%Color and Shape:SolidMolecular weight:451.54Ref: TM-T16695
1mg82.00€2mg96.00€5mg159.00€10mg226.00€25mg435.00€50mg648.00€100mg924.00€200mg1,225.00€1mL*10mM (DMSO)168.00€Senexin B
CAS:Senexin B is a potent and selective inhibitor of CDK8/19(CDK8 and CDK19 with Kds of 140 nM and 80 nM).Formula:C27H26N6OPurity:99.67%Color and Shape:SolidMolecular weight:450.53Ref: TM-T8430
1mg97.00€2mg131.00€5mg188.00€10mg305.00€25mg487.00€50mg655.00€100mg905.00€1mL*10mM (DMSO)215.00€GDC-0575
CAS:GDC-0575 (ARRY-575) is a highly-selective oral small-molecule Chk1 inhibitor(IC50 of 1.2 nM).Formula:C16H20BrN5OPurity:≥95%Color and Shape:SolidMolecular weight:378.27CCT-251921
CAS:CCT-251921 is a potent, selective, and orally bioavailable CDK8 inhibitor (IC50: 2.3 nM).Formula:C21H23ClN6OPurity:97.74%Color and Shape:SolidMolecular weight:410.9Ref: TM-T14901
1mg95.00€5mg221.00€10mg324.00€25mg548.00€50mg785.00€100mg1,074.00€1mL*10mM (DMSO)202.00€PROTAC CDK9/CycT1 Degrader-2
PROTAC CDK9/CycT1 Degrader-2 inhibits CDK9 with an IC50 of 45 nM [1].Formula:C30H36N4O6S2Purity:98%Color and Shape:SolidMolecular weight:612.76BMS-1001 hydrochloride
CAS:BMS-1001 hydrochloride is an orally active inhibitor of human PD-1/PD-L1 immune checkpoint with low-toxicity in cells.BMS-1001 alleviates the inhibitory effectFormula:C35H35ClN2O7Purity:97.36%Color and Shape:SolidMolecular weight:631.11Ref: TM-T10565
1mg56.00€5mg127.00€10mg197.00€25mg401.00€50mg645.00€100mg1,026.00€200mg1,378.00€1mL*10mM (DMSO)172.00€ZCL278
CAS:ZCL278 is a selective Cdc42 GTPase inhibitor.Formula:C21H19BrClN5O4S2Purity:96.29% - 99.72%Color and Shape:SolidMolecular weight:584.89Ref: TM-T1855
5mg50.00€10mg79.00€25mg136.00€50mg221.00€100mg310.00€200mg497.00€500mg805.00€1mL*10mM (DMSO)79.00€CID 5951923
CAS:CID 5951923 is an inhibitor of KLF5 transcription factor with an IC50 of 603 nM.Formula:C16H18N2O7SPurity:100.00%Color and Shape:SolidMolecular weight:382.39Barasertib-HQPA
CAS:Barasertib-HQPA (AZD2811) is a highly selective Aurora B inhibitor (IC50: 0.37 nM) and demonstrates ~3,700-fold greater selectivity than Aurora A.Formula:C26H30FN7O3Purity:98.43% - 99.29%Color and Shape:SolidMolecular weight:507.56TH588
CAS:TH588 is nudix hydrolase family inhibitor that effectively and selectively engages and inhibits the MTH1(IC50: 5 nM) in cells.Formula:C13H12Cl2N4Purity:96.05% - 99.82%Color and Shape:SolidMolecular weight:295.17AAPK-25
CAS:AAPK-25, a dual Aurora/PLK inhibitor, disrupts mitosis, induces apoptosis, and has antitumor properties.Formula:C21H13Cl2N3O2SPurity:97.79%Color and Shape:SolidMolecular weight:442.32Ref: TM-T10215
1mg95.00€5mg202.00€10mg303.00€25mg550.00€50mg825.00€100mg1,198.00€1mL*10mM (DMSO)233.00€Palbociclib monohydrochloride
CAS:Palbociclib monohydrochloride (PD 0332991 hydrochloride) is a selective inhibitor of CDK4/6, with no inhibition against a panel of 36 additional protein kinasesFormula:C24H29N7O2·HClPurity:100% - 99.91%Color and Shape:SolidMolecular weight:483.99JSH-150
CAS:JSH-150 is a highly selective CDK9 inhibitor(IC50 : 1 nM).Formula:C24H33ClN6O2SPurity:100% - 99.96%Color and Shape:SolidMolecular weight:505.08LIMK-IN-22j
CAS:LIMK-IN-22j (LIMK inhibitor 22j) is an effective and selective inhibitor of LIMK.Formula:C20H21BrN8Purity:99.17%Color and Shape:SolidMolecular weight:453.34
