Cell Cycle/Checkpoint
Cell cycle/checkpoint inhibitors are compounds that disrupt the normal progression of the cell cycle, particularly at key regulatory checkpoints. These inhibitors are crucial for studying cell division, understanding cancer cell proliferation, and developing anti-cancer therapies. By targeting specific phases of the cell cycle, these inhibitors can induce cell cycle arrest, leading to apoptosis or senescence in rapidly dividing cells. At CymitQuimica, we offer a diverse range of high-quality cell cycle/checkpoint inhibitors to support your research in cancer biology, cell biology, and drug development.
Subcategories of "Cell Cycle/Checkpoint"
- Aurora Kinase
- CDK
- Cell Cycle Arrest
- Chk
- c-Myc
- Dynamin
- DYRK
- Ferroptosis
- HSP
- Integrin
- Kinesin
- KSP
- LIM Kinase
- Microtubule Associated
- PKC
- PLK
- Rho
- ROCK
- Wee1
Show 11 more subcategories
Products of "Cell Cycle/Checkpoint"
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AZD-5597
CAS:AZD-5597 ((S)-(4-((5-Fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimidin-2-yl)amino)phenyl)(3-(methylamino)pyrrolidin-1-yl)methanone) is a potentFormula:C23H28FN7OPurity:98.01%Color and Shape:SolidMolecular weight:437.51Ref: TM-T21544
1mg57.00€5mg120.00€10mg187.00€25mg416.00€50mg655.00€100mg924.00€1mL*10mM (DMSO)144.00€Sapacitabine
CAS:Sapacitabine (CS682) is a nucleoside analog precursor with anticancer activity used in the study of leukemia.Formula:C26H42N4O5Purity:98.82%Color and Shape:SolidMolecular weight:490.64T4 RNA ligase
T4 RNA ligase is an enzyme that facilitates the ligation of single-stranded DNA.Purity:98%Color and Shape:Odour SolidMonastrol
CAS:Monastrol ((±)-Monastrol) is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.Formula:C14H16N2O3SPurity:98.59% - 99.19%Color and Shape:SolidMolecular weight:292.35Ref: TM-T4048
1mg48.00€5mg78.00€10mg97.00€25mg188.00€50mg311.00€100mg502.00€500mg1,074.00€1mL*10mM (DMSO)87.00€Enrofloxacin
CAS:Enrofloxacin (BAY-Vp2674) is a veterinary antibacterial agent, used in poultry.Formula:C19H22FN3O3Purity:100% - 99.89%Color and Shape:Pale Yellow CrystalsMolecular weight:359.39PF-06873600
CAS:PF-06873600: oral CDK inhibitor (CDK2/4/6), Ki 0.09-0.16 nM, potential anticancer drug.Formula:C20H27F2N5O4SPurity:98.77% - 99.58%Color and Shape:SolidMolecular weight:471.52Ref: TM-T8463
1mg57.00€5mg120.00€10mg188.00€25mg354.00€50mg588.00€100mg938.00€200mg1,264.00€1mL*10mM (DMSO)131.00€Zimberelimab
CAS:Zimberelimab (GLS-010) is a humanized antibody targeting PD-1, with anticancer activity.Purity:95%Color and Shape:Liquid7-Methylguanosine
CAS:7-Methylguanosine is a novel cNIIIB nucleotidase inhibitor (IC50 : 87.8 ± 7.5 μM).Formula:C11H16N5O5Purity:98.11%Color and Shape:SolidMolecular weight:298.282′-O-Methylcytidine
CAS:2′-O-Methylcytidine inhibits NS5B-catalyzed RNA synthesis in vitro, in a manner that is competitive with substrate nucleoside triphosphate.Formula:C10H15N3O5Purity:99.81%Color and Shape:SolidMolecular weight:257.24Ilorasertib hydrochloride
CAS:Ilorasertib hydrochloride (ABT-348 hydrochloride) is an ATP-competitive multitargeted kinase inhibitor, which inhibits Aurora C, Aurora B, and Aurora A (IC50s:Formula:C25H22ClFN6O2SPurity:98.34%Color and Shape:SolidMolecular weight:525TK216
CAS:TK216 is a potent inhibitor of E26 transformation-specific (ETS) with anticancer activity.Formula:C19H15Cl2NO3Purity:97.22%Color and Shape:SolidMolecular weight:376.23(S)-Monastrol
CAS:Monastrol is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.Formula:C14H16N2O3SPurity:98%Color and Shape:SolidMolecular weight:292.356-Mercaptopurine
CAS:6-Mercaptopurine (6-MP) is an antimetabolite antineoplastic agent with immunosuppressant properties.Formula:C5H4N4SPurity:99.53% - 99.63%Color and Shape:Yellow Crystalline Powder SolidMolecular weight:152.18KIF18A-IN-15
CAS:KIF18A-IN-15 (Compound Example 36) is a KIF18A inhibitor, available in two forms, EX36-A and its enantiomer EX36-B, both with an IC50 range of 0.01-0.1 μM. These compounds inhibit the viability of OVCAR-3 cells, with IC50 values of 0.01-0.1 μM for EX36-A and 0-0.01 μM for EX36-B. KIF18A-IN-15 is applicable in research on tumors, including colon, breast, and lung cancers.Formula:C25H33F3N6O5SColor and Shape:SolidMolecular weight:586.63Voruciclib hydrochloride
CAS:Voruciclib hydrochloride is an orally active and selective inhibitor of CDK (Ki: 0.626 nM-9.1 nM).Formula:C22H20Cl2F3NO5Purity:98%Color and Shape:SolidMolecular weight:506.33-Methylcytidine
CAS:3-Methylcytidine as biomarkers of four different types of cancer: lung cancer, gastric cancer, colon cancer, and breast cancer.Formula:C10H15N3O5Purity:98%Color and Shape:SolidMolecular weight:257.24Kif15-IN-2
CAS:Kif15-IN-2 is a kinesin Kif15 inhibitor with potential anticancer activity and can be used in prostate cancer research.Formula:C20H20N6O4SPurity:98.17%Color and Shape:SolidMolecular weight:440.48CDK1-IN-2
CAS:CDK1-IN-2 (cdk1 inhibitor 2) is a CDK1 inhibitor with IC50 of 5.8 μM.Formula:C17H11ClN2OPurity:98.41%Color and Shape:SoildMolecular weight:294.73Ref: TM-T64373
1mg50.00€5mg107.00€10mg170.00€25mg354.00€50mg567.00€100mg810.00€500mg1,644.00€1mL*10mM (DMSO)103.00€NU6140
CAS:NU6140 is a selective inhibitor of CDK2-cyclin A (IC50, 0.41 μM).Formula:C23H30N6O2Purity:98.33%Color and Shape:SolidMolecular weight:422.52Ref: TM-T16359
2mg42.00€5mg64.00€10mg97.00€25mg187.00€50mg301.00€100mg437.00€200mg612.00€1mL*10mM (DMSO)71.00€Bisindolylmaleimide X hydrochloride
CAS:Bisindolylmaleimide X hydrochloride (BIM-X hydrochloride) is a potent and selective PKC inhibitor. It is also a potent CDK2 antagonist (IC50: 200 nM).Formula:C26H25ClN4O2Purity:98.5%Color and Shape:SolidMolecular weight:460.96
