CDK
CDK (Cyclin-Dependent Kinase) inhibitors are compounds that block the activity of CDKs, a group of protein kinases that regulate the cell cycle, transcription, and other cellular processes. CDKs are activated by binding to cyclins, and their activity is crucial for the progression of cells through different phases of the cell cycle. Inhibiting CDKs can halt cell division, leading to cell cycle arrest and apoptosis, particularly in cancer cells where CDKs are often dysregulated. CDK inhibitors are widely used in cancer research and have therapeutic potential in treating various cancers. At CymitQuimica, we provide a comprehensive selection of high-quality CDK inhibitors to support your research in cell cycle control, cancer, and therapeutic development.
Products of "CDK"
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Amantadine hydrochloride
CAS:Amantadine hydrochloride (CI-719) is an antiviral that is used in the prophylactic or symptomatic treatment of influenza A and Parkinson disease.Formula:C10H18ClNPurity:99.98%Color and Shape:Solid CrystallineMolecular weight:187.71(S)-Enitociclib
CAS:(S)-Enitociclib (VIP152) is a selective CDK9 inhibitor that inhibits the transcription of anti-apoptotic and pro-survival proteins.Formula:C19H18F2N4O2SPurity:98.04%Color and Shape:SolidMolecular weight:404.43AS2863619
CAS:AS2863619 is an oral inhibitor of cyclin-dependent kinase(CDK8) and CDK19. Inhibition of CDK8/19 enhances STAT5 activation.Cost-effective and quality-assured.Formula:C16H14Cl2N8OPurity:100%Color and Shape:SolidMolecular weight:405.24Ref: TM-T8378
1mg131.00€2mg180.00€5mg274.00€10mg432.00€25mg715.00€50mg1,008.00€100mg1,359.00€1mL*10mM (DMSO)303.00€CDK8/19-IN-51
CAS:CDK8/19-IN-51 is a CDK8 and CDK19 inhibitor with anticancer activity, used in research on colorectal and gastric cancers.Formula:C23H22N6O2Purity:100% - 98.65%Color and Shape:SoildMolecular weight:414.46WAY-647802
CAS:WAY-647802 is a CDK inhibitor.Formula:C11H14N4O3Purity:98.38%Color and Shape:SolidMolecular weight:250.25Bisindolylmaleimide X hydrochloride
CAS:Bisindolylmaleimide X hydrochloride (BIM-X hydrochloride) is a potent and selective PKC inhibitor. It is also a potent CDK2 antagonist (IC50: 200 nM).Formula:C26H25ClN4O2Purity:98.5%Color and Shape:SolidMolecular weight:460.96THZ1
CAS:THZ1 (CDK7 inhibitor) is a selective inhibitor of CDK7, binding to the Cys residue located at the outer end of the classical kinase domain. Cost-effective and quality-assured.Formula:C31H28ClN7O2Purity:95.09% - 99.27%Color and Shape:SolidMolecular weight:566.05CDK2-IN-4
CAS:CDK2-IN-4 is a potent and selective inhibitor of CDK2 with an IC50 of 44 nM for CDK2/cyclin A.Formula:C23H18N6O2SPurity:97.24% - 99.10%Color and Shape:SolidMolecular weight:442.49Ref: TM-T14916
1mg87.00€5mg202.00€10mg321.00€25mg550.00€50mg753.00€100mg1,074.00€1mL*10mM (DMSO)240.00€ON-013100
CAS:ON-013100 is an antineoplastic drug. ON-013100 also acts as a mitotic inhibitor that could inhibit Cyclin D1 expression.Formula:C19H22O7SPurity:98.27%Color and Shape:SolidMolecular weight:394.44Ref: TM-T16391
1mg50.00€5mg74.00€10mg105.00€25mg182.00€50mg283.00€100mg425.00€200mg602.00€1mL*10mM (DMSO)64.00€CDK2-IN-40
CAS:CDK9-IN-40 is an inhibitor of CDK2 (Cyclin-dependent kinase 2). It effectively inhibits CDK2/Cyclin E1, with an IC50 of ≤ 10 nM.Formula:C16H21N7O2Color and Shape:SolidMolecular weight:343.384Ribociclib succinate
CAS:Ribociclib succinate (LEE011 succinate) is a highly specific CDK4/6 inhibitor (IC50: 10 nM and 39 nM, respectively).Formula:C27H36N8O5Purity:99.90%Color and Shape:SolidMolecular weight:552.63Ref: TM-T15732
2mg35.00€5mg51.00€10mg73.00€25mg97.00€50mg115.00€100mg168.00€200mg271.00€500mg484.00€1mL*10mM (DMSO)64.00€BML-259
CAS:BML-259 inhibits CDK5/CDK2 (IC50: 64/98 nM) for cancer and neurodegeneration research.Formula:C14H16N2OSPurity:99.68%Color and Shape:SolidMolecular weight:260.35Ref: TM-T36964
5mg50.00€10mg85.00€25mg169.00€50mg279.00€100mg487.00€500mg1,035.00€1mL*10mM (DMSO)52.00€SEL120-34A
CAS:SEL120-34A inhibits CDK8 (IC50: 4.4 nM) & CDK19 (10.4 nM), less on CDK9 (1070 nM), has antitumor properties.Formula:C15H18Br2N4Purity:100% - 99.7%Color and Shape:SolidMolecular weight:414.14CDK8-IN-1
CAS:CDK8-IN-1 is a selective CDK8 inhibitor (IC50: 3 nM).Formula:C11H8F3N3OPurity:97.09%Color and Shape:SolidMolecular weight:255.2Ref: TM-T10740
1mg87.00€5mg216.00€10mg311.00€25mg525.00€50mg707.00€100mg944.00€1mL*10mM (DMSO)240.00€BGG463
CAS:BGG463 (K 0859) can inhibit c-ABL-T334I, BCR-ABL and BCR-ABL-T315I variants with an IC50 of 0.25 μM, 0.09 μM and 0.590 μM, respectively.Formula:C30H29F3N6O3Purity:100% - 95.05%Color and Shape:SolidMolecular weight:578.58Ref: TM-T4618
1mg62.00€2mg87.00€5mg119.00€10mg188.00€25mg350.00€50mg505.00€100mg730.00€1mL*10mM (DMSO)154.00€ALSTERPAULLONE
CAS:Alsterpaullone is a Cyclin-Dependent Kinase Inhibitor, Mediated Toxicity in HeLa Cells Through Apoptosis-Inducing EffecFormula:C16H11N3O3Purity:99.39%Color and Shape:SolidMolecular weight:293.28Ref: TM-T7426
1mg58.00€5mg116.00€10mg183.00€25mg313.00€50mg449.00€100mg620.00€200mg835.00€1mL*10mM (DMSO)111.00€Seliciclib
CAS:Seliciclib (Roscovitine) is a potent inhibitor of Cdk2/cyclin E, also inhibits Cdk7, Cdk5 and Cdc2. Seliciclib has antitumor effect. Cost-effective, quality assurance.Formula:C19H26N6OPurity:97.15% - 99.88%Color and Shape:White To Off-White SolidMolecular weight:354.45Samuraciclib hydrochloride
CAS:Samuraciclib HCl is an oral CDK7 inhibitor (IC50: 41 nM), 45-230x selective over CDK1/2/5/9, inhibiting breast cancer growth (GI50: 0.2-0.3 μM).Formula:C22H31ClN6OPurity:98.99% - 99.8%Color and Shape:SolidMolecular weight:430.97Ref: TM-T10898
1mg114.00€5mg235.00€10mg376.00€25mg628.00€50mg894.00€100mg1,216.00€1mL*10mM (DMSO)259.00€NVP-LCQ195
CAS:NVP-LCQ195 (LCQ-195) (AT9311) is a potent inhibitor of CDK1, CDK2, CDK3 and CDK5 (IC50: 1-42 nM).Formula:C17H19Cl2N5O4SPurity:100% - 99.36%Color and Shape:SolidMolecular weight:460.33Ref: TM-TQ0068
1mg48.00€5mg97.00€10mg145.00€25mg269.00€50mg395.00€100mg563.00€200mg743.00€1mL*10mM (DMSO)99.00€ML167
CAS:ML167 (CID44968231) is a highly selective Cdc2-like kinase 4 (Clk4) inhibitor.Formula:C19H17N3O3Purity:100% - 98.85%Color and Shape:SolidMolecular weight:335.36Ref: TM-T2670
2mg34.00€5mg49.00€10mg74.00€25mg142.00€50mg235.00€100mg349.00€200mg497.00€1mL*10mM (DMSO)49.00€
