CDK
CDK (Cyclin-Dependent Kinase) inhibitors are compounds that block the activity of CDKs, a group of protein kinases that regulate the cell cycle, transcription, and other cellular processes. CDKs are activated by binding to cyclins, and their activity is crucial for the progression of cells through different phases of the cell cycle. Inhibiting CDKs can halt cell division, leading to cell cycle arrest and apoptosis, particularly in cancer cells where CDKs are often dysregulated. CDK inhibitors are widely used in cancer research and have therapeutic potential in treating various cancers. At CymitQuimica, we provide a comprehensive selection of high-quality CDK inhibitors to support your research in cell cycle control, cancer, and therapeutic development.
Products of "CDK"
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KenPaullone
CAS:KenPaullone (9-Bromopaullone), a potent CDK1, CDK2 and CDK5 inhibitor, as new enhancer for iTreg cell differentiation.Formula:C16H11BrN2OPurity:97.14% - 98.99%Color and Shape:Tan SolidMolecular weight:327.18Ref: TM-T2247
1mg38.00€2mg49.00€5mg70.00€10mg95.00€25mg188.00€50mg319.00€100mg474.00€500mg1,074.00€1mL*10mM (DMSO)74.00€Palbociclib monohydrochloride
CAS:Palbociclib monohydrochloride (PD 0332991 hydrochloride) is a selective inhibitor of CDK4/6, with no inhibition against a panel of 36 additional protein kinasesFormula:C24H29N7O2·HClPurity:100% - 99.91%Color and Shape:SolidMolecular weight:483.99JSH-150
CAS:JSH-150 is a highly selective CDK9 inhibitor(IC50 : 1 nM).Formula:C24H33ClN6O2SPurity:100% - 99.96%Color and Shape:SolidMolecular weight:505.08CDK8/19-IN-1
CAS:CDK8/19-IN-1 is a selective and oral bioavailable CDK8/19 dual inhibitor (IC50s: 0.46 nM, 0.99 nM, and 270 nM for CDK8, CDK19, and CDK9).Formula:C19H18N4O4S2Purity:98%Color and Shape:SolidMolecular weight:430.5CDK12-IN-E9
CAS:CDK12-IN-E9 is a potent and selective covalent CDK12 inhibitor and non-covalent CDK9 inhibitor while avoiding ABC transporter-mediated efflux.Formula:C24H30N6O2Color and Shape:SolidMolecular weight:434.53GP-82996
CAS:GP-82996 (CINK4) inhibits CDK4/6; IC50s: 1.5 μM (CDK4/D1), 5.6 μM (CDK6/D1), 25 μM (Cdk5/p35); triggers U2OS cancer cell apoptosis.Formula:C27H32N6OPurity:99.57%Color and Shape:SolidMolecular weight:456.58THAL-SNS-032
CAS:THAL-SNS-032 is a selective CDK9 degrader PROTAC.Formula:C40H52N8O10S2Purity:99.68%Color and Shape:SolidMolecular weight:869.02Ref: TM-T17069
1mg116.00€5mg274.00€10mg410.00€25mg657.00€50mg934.00€100mg1,264.00€1mL*10mM (DMSO)411.00€AZD-5597
CAS:AZD-5597 ((S)-(4-((5-Fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimidin-2-yl)amino)phenyl)(3-(methylamino)pyrrolidin-1-yl)methanone) is a potentFormula:C23H28FN7OPurity:98.01%Color and Shape:SolidMolecular weight:437.51Ref: TM-T21544
1mg57.00€5mg120.00€10mg187.00€25mg416.00€50mg655.00€100mg924.00€1mL*10mM (DMSO)144.00€AG-494
CAS:AG-494 (Tyrphostin B48) is an inhibitor of epidermal growth factor receptor kinase.Formula:C16H12N2O3Purity:98.69%Color and Shape:SolidMolecular weight:280.28(R)-CR8
CAS:(R)-CR8 ((R)-Isomer) is a potent and selective CDK inhibitor.Formula:C24H29N7OPurity:98.41%Color and Shape:SolidMolecular weight:431.53Ref: TM-T12617L
1mg66.00€5mg144.00€10mg210.00€25mg356.00€50mg525.00€100mg747.00€1mL*10mM (DMSO)159.00€PF-06873600
CAS:PF-06873600: oral CDK inhibitor (CDK2/4/6), Ki 0.09-0.16 nM, potential anticancer drug.Formula:C20H27F2N5O4SPurity:98.77% - 99.58%Color and Shape:SolidMolecular weight:471.52Ref: TM-T8463
1mg57.00€5mg120.00€10mg188.00€25mg354.00€50mg588.00€100mg938.00€200mg1,264.00€1mL*10mM (DMSO)131.00€Garcinone C
CAS:Garcinone C, a xanthone from Garcinia oblongifolia, is anti-inflammatory, promotes healing, and may fight some cancers.Formula:C23H26O7Purity:98.93%Color and Shape:SolidMolecular weight:414.45Voruciclib hydrochloride
CAS:Voruciclib hydrochloride is an orally active and selective inhibitor of CDK (Ki: 0.626 nM-9.1 nM).Formula:C22H20Cl2F3NO5Purity:98%Color and Shape:SolidMolecular weight:506.36-(Dimethylamino)purine
CAS:6-(Dimethylamino)purine (N,N-Dimethyladenine) is a serine threonine protein kinase and CDK inhibitorFormula:C7H9N5Purity:99.01% - 99.77%Color and Shape:SolidMolecular weight:163.18CDK1-IN-2
CAS:CDK1-IN-2 (cdk1 inhibitor 2) is a CDK1 inhibitor with IC50 of 5.8 μM.Formula:C17H11ClN2OPurity:98.41%Color and Shape:SoildMolecular weight:294.73Ref: TM-T64373
1mg50.00€5mg107.00€10mg170.00€25mg354.00€50mg567.00€100mg810.00€500mg1,644.00€1mL*10mM (DMSO)103.00€NU6140
CAS:NU6140 is a selective inhibitor of CDK2-cyclin A (IC50, 0.41 μM).Formula:C23H30N6O2Purity:98.33%Color and Shape:SolidMolecular weight:422.52Ref: TM-T16359
2mg42.00€5mg64.00€10mg97.00€25mg187.00€50mg301.00€100mg437.00€200mg612.00€1mL*10mM (DMSO)71.00€LDC4297
CAS:LDC4297 (LDC044297) is a potent and selective CDK7 inhibitor.Formula:C23H28N8OPurity:98.25%Color and Shape:SolidMolecular weight:432.52RGB-286638 free base
CAS:RGB-286638 free base inhibits CDKs (1-5 nM), weaker on CDK7/6.Formula:C29H35N7O4Purity:97.29% - 99.91%Color and Shape:SolidMolecular weight:545.63Cirtuvivint
CAS:Cirtuvivint (SM08502) is a potent and orally active CDC-like kinase (CLK) inhibitor that can be used to study arthritis.Formula:C24H25N7OPurity:100% - 100%Color and Shape:SolidMolecular weight:427.5Rafoxanide
CAS:Rafoxanide as a dual CDK4/6 inhibitor for the treatment of skin cancer.Formula:C19H11Cl2I2NO3Purity:99.47%Color and Shape:Slight Yellowish Brown Injectable Solution &White Oral SolutionMolecular weight:626.01
