HSP
HSP (Heat Shock Protein) inhibitors target HSPs, a family of molecular chaperones that assist in protein folding, stability, and protection against stress-induced damage. HSPs are often upregulated in cancer cells, helping them survive under stressful conditions such as hypoxia and chemotherapy. Inhibiting HSPs can disrupt these protective mechanisms, leading to cell death. HSP inhibitors are therefore valuable in cancer therapy and research into stress responses. At CymitQuimica, we provide a comprehensive range of high-quality HSP inhibitors to support your research in protein homeostasis, stress responses, and oncology.
Products of "HSP"
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NDNA4
NDNA4 (compound 17) is a selective Hsp90α inhibitor (IC50: 0.34 μM), characterized by its permanent charge and low membrane permeability.Formula:C31H35F3N2O5SPurity:98%Color and Shape:SolidMolecular weight:604.68Paeoniflorin
CAS:Paeoniflorin (Peoniflorin) is a herbal constituent extracted from the root of Paeonia albiflora Pall.Formula:C23H28O11Purity:96.9% - 97.16%Color and Shape:White Fine PowderMolecular weight:480.46Hsp110-STAT3 interaction-IN-2
Hsp110-STAT3 interaction-IN-2 (compound 10b) is an inhibitor of the Hsp110-STAT3 interaction. It is utilized in research related to pulmonary arterial hypertension (PAH).Formula:C24H18F3N5O3Color and Shape:SolidMolecular weight:481.43Tanespimycin
CAS:Tanespimycin (KOS 953) (17-AAG) is an inhibitor of Hsp90 that selectively inhibits BT474 tumor cell Hsp90 (IC50: 5 nM).Formula:C31H43N3O8Purity:99.07% - 99.83%Color and Shape:Dark Purple SolidMolecular weight:585.69KU-177
CAS:KU-177 is an Aha1 inhibitor that disrupts the interaction between Hsp90 and Aha1, eliminating cell proliferation and PI resistance induced by elevated AHSA1.Formula:C27H23NO8Purity:97.34% - 98.54%Color and Shape:SolidMolecular weight:489.47Calyxin H
CAS:Calyxin H at 1uM can increase the expression of heat shock factor 1 (HSF1), it has a possible application as a heat shock protein (HSP) inducer.Formula:C35H34O7Purity:98%Color and Shape:SolidMolecular weight:566.64SNX0723
CAS:SNX0723 is a potent Hsp90 Inhibitor with anti-Plasmodium activity.Formula:C22H26FN3O3Purity:99.86%Color and Shape:SolidMolecular weight:399.46Ref: TM-T28824
1mg89.00€5mg188.00€10mg316.00€25mg512.00€50mg702.00€100mg940.00€500mgTo inquire1mL*10mM (DMSO)207.00€7-Aminocephalosporanic acid
CAS:7-Aminocephalosporanic acid (7-ACA) is used for synthesis of cephalosporin antibiotics and intermediates.Formula:C10H12N2O5SPurity:91.05% - 98.22%Color and Shape:White Solid PowderMolecular weight:272.28HSP90-IN-23
HSP90-IN-23 (Comp 12-1), a heat shock protein 90 (HSP90) inhibitor, exhibits potent activity with an IC50 of 9nM.Formula:C22H24N2O6SPurity:98%Color and Shape:SolidMolecular weight:444.5DN401
CAS:DN401 is a potent TRAP1 and Hsp90 Inhibitor( IC50 = 79 nM for TRAP1, IC50 = 698 nM for Hsp90) with potent anticancer activity.Formula:C13H9BrClN5O2Purity:100%Color and Shape:SolidMolecular weight:382.6Ref: TM-T27193
1mg185.00€5mg409.00€10mg605.00€25mg938.00€50mg1,293.00€100mg1,738.00€500mg3,496.00€1mL*10mM (DMSO)406.00€TRAP1-IN-2
CAS:TRAP1-IN-2, also known as compound 36, is a selective degrader of the TRAP1 client protein that does not affect Hsp90-cytosolic clients.Formula:C46H42F6N2O5P2Purity:98%Color and Shape:SolidMolecular weight:878.77Ethoxyquin
CAS:Ethoxyquin (Santoflex) is an antioxidant used in animal feeds.Formula:C14H19NOPurity:95.94%Color and Shape:Yellow Liquid Mercaptan-Like Odor (Ntp 1992)Molecular weight:217.31Dihydroberberine
CAS:Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities.Formula:C20H19NO4Purity:93.77%Color and Shape:SolidMolecular weight:337.37Arimoclomol
CAS:Arimoclomol (BRX-220 free base) is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (Formula:C14H20ClN3O3Purity:99.81%Color and Shape:SolidMolecular weight:313.78Ref: TM-T13553
1mg115.00€5mg249.00€10mg369.00€25mg562.00€50mg787.00€100mg1,054.00€200mg1,406.00€1mL*10mM (DMSO)249.00€AT-533
CAS:AT-533 inhibits Hsp90, HSV, hinders HIF-1α/VEGF/VEGFR-2, Erk1/2, FAK, Akt/mTOR/p70S6K, and blocks tumor growth, angiogenesis, and HUVEC activities.Formula:C23H30N4O3Purity:99.54%Color and Shape:SoildMolecular weight:410.51Ref: TM-T67836
1mg51.00€5mg111.00€10mg170.00€25mg313.00€50mg467.00€100mg672.00€200mg905.00€1mL*10mM (DMSO)117.00€Novobiocin Sodium
CAS:Novobiocin Sodium (Albamycinsodium) binds to DNA gyrase and blocks adenosine triphosphatase (ATPase) activity. Novobiocin sodium is an antibiotic compound.Formula:C31H35N2NaO11Purity:99% - 99.28%Color and Shape:SolidMolecular weight:634.61Grp94 Inhibitor-1
CAS:Grp94 Inhibitor-1 is a potent, selective Grp94 inhibitor (IC50 : 2 nM).Formula:C22H28N2O2Purity:97.02%Color and Shape:SolidMolecular weight:352.47PF-04929113 Mesylate
CAS:PF-04929113 Mesylate (SNX-5422 Mesylate), a prodrug of SNX-2112, is an orally available Hsp90 inhibitor (Kd: 41 nM) and also induces Her-2 degradation (IC50: 37Formula:C26H34F3N5O7SPurity:99% - 99.46%Color and Shape:SolidMolecular weight:617.63Ref: TM-T4342
1mg78.00€2mg100.00€5mg159.00€10mg288.00€25mg419.00€50mg615.00€100mg878.00€500mg1,776.00€1mL*10mM (DMSO)233.00€HS-27
CAS:HS-27 is a fluorescently-tethered inhibitor of Hsp90 with SNX-5422 tethered via a PEG linker to a fluorescein isothiocyanate or FITC.Formula:C52H60N6O12SPurity:97.09%Color and Shape:SolidMolecular weight:993.13Ref: TM-T18018
1mg90.00€5mg215.00€10mg344.00€25mg612.00€50mg848.00€100mg1,159.00€1mL*10mM (DMSO)378.00€Onalespib
CAS:Onalespib (AT13387) is an oral Hsp90 inhibitor with anticancer potential, disrupting tumor cell growth and survival.Formula:C24H31N3O3Purity:98.05% - 99.82%Color and Shape:SolidMolecular weight:409.52
