Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Products of "Chromatin/Epigenetics"
Sort by
TCS-PIM-1-4a
CAS:SMI-4a, a Pim inhibitor, activates AMPK, halts mTORC1, and kills various myeloid/lymphoid cells (IC50=0.8-40μM).Formula:C11H6F3NO2SPurity:99.89%Color and Shape:SolidMolecular weight:273.23YT117R
YT117R is a PROTAC that targets degradation of FKBP12 and BRD4.Formula:C50H52ClN9O7SColor and Shape:SolidMolecular weight:958.52F5446
CAS:F5446 is a selective small molecule SUV39H1 methyltransferase inhibitor, promotes apoptosis in colorectal cancer cells by inhibiting the deposition of H3K9me3.Formula:C26H17ClN2O8SPurity:98.56%Color and Shape:SolidMolecular weight:552.944β-Hydroxywithanolide E
CAS:4bHWE inhibits colon cancer growth, alters splicing, is anti-inflammatory, aids in diabetes/obesity, and may be chemopreventive.Formula:C28H38O8Purity:98%Color and Shape:SolidMolecular weight:502.604ZEN-3411
CAS:ZEN-3411 is an BET inhibitor that inhibits BRD4(BD1), BRD4(BD2), and BRD4(BD1BD2) and suppresses the growth of tumor cells overproducing BET proteins.Formula:C21H20N4O2Purity:97.42% - 97.77%Color and Shape:SolidMolecular weight:360.41GSK3368715 dihydrochloride
CAS:GSK3368715 dihydrochloride (EPZ019997 dihydrochloride) is a PRMTs inhibitor , with anticancer activity, for the study of advanced solid tumors.Formula:C20H40Cl2N4O2Purity:99.66% - 99.66%Color and Shape:SolidMolecular weight:439.46Acetyl Pentapeptide-1 acetate
Acetyl Pentapeptide-1 acetate is an histone deacetylase inhibitor.Formula:C34H55N9O12Purity:99.09%Color and Shape:SolidMolecular weight:781.86Ref: TM-T38318L
1mg87.00€2mg124.00€5mg187.00€10mg284.00€25mg452.00€50mg645.00€100mg867.00€200mg1,159.00€BET/Aurora kinase-IN-1
CAS:BET/Aurora kinase-IN-1 (Compound 38) is a dual inhibitor of BET and Aurora kinases. It exhibits antiproliferative activity against various tumor cell lines and demonstrates significant antitumor efficacy in xenograft models of renal cell carcinoma and colon cancer, with tumor growth inhibition (TGI) rates of 45.99% and 53.06%, respectively.Formula:C25H30FN7OColor and Shape:SolidMolecular weight:463.55LSD1-IN-30
CAS:LSD1-IN-30 is a lysine-specific demethylase 1 (LSD1) inhibitor with anticancer activity for the study of small cell lung cancer and acute myeloid leukemia.Formula:C15H14N2O3Purity:98.42%Color and Shape:SoildMolecular weight:270.28CFT-1297
CFT-1297 is a BET PROTAC degrader that targets BRD4 for degradation.Formula:C47H51N9O4Color and Shape:SolidMolecular weight:805.97LLY-283
CAS:LLY-283, PRMT5 inhibitor, IC50 22 nM, Kd 6 nM, oral, selective, with antitumor effects.Formula:C17H18N4O4Purity:98.79%Color and Shape:SolidMolecular weight:342.35PROTAC SMARCA2 degrader-24
CAS:PROTAC SMARCA2 degrader-24 (Compound 34) is a SMARCA2 PROTAC degrader with a DC50 of less than 0.1 µM in HeLa cells. It also degrades SMARCA4 in HeLa cells, exhibiting a DC50 greater than 10 µM.Formula:C45H56N10O5SColor and Shape:SolidMolecular weight:849.06OTS186935 FA
OTS186935 FA is a protein methyltransferase SUV39H2 inhibitor.OTS186935 FA inhibits tumor growth in MDA-MB-231 breast cancer cells.Formula:C26H28ClN5O4Purity:98.16%Color and Shape:SoildMolecular weight:509.98Ref: TM-T12344L1
1mg97.00€5mg235.00€10mg393.00€25mg710.00€50mg1,103.00€100mg1,539.00€500mg3,068.00€1mL*10mM (DMSO)269.00€JAK3/BTK-IN-1
CAS:JAK3/ BTk-in-1 is a dual JAK3/BTK inhibitor that specifically targets and inhibits Janus kinase 3 (JAK3) and Bruton's tyrosine kinase (BTK), two importantFormula:C25H28N8OPurity:97.89%Color and Shape:SolidMolecular weight:456.54L134
L134, an effective PROTAC BRD4 degrader, exhibits a DC50 value of 7.36 nM. The degradation of BRD4 by L134 is mediated through the ubiquitin-proteasome system in a DCAF11-dependent manner.Formula:C48H51ClF3N7O7SColor and Shape:SolidMolecular weight:962.47CBP/p300-IN-2
CAS:CBP/EP300-IN-2 is an inhibitor of CBP/EP300 (IC50s: 1.07 nM and 5.96 nM for CBP/HTRF and Myc).Formula:C27H29F2N7O2Purity:98%Color and Shape:SolidMolecular weight:521.56RBN-2397
CAS:RBN-2397 is a potent, selective and orally active accross species NAD+ competitive PARP7 inhibitor with IC50 less than 3 nM.Formula:C20H23F6N7O3Purity:98.48% - 99.96%Color and Shape:SolidMolecular weight:523.43Ref: TM-T12695
1mg130.00€5mg311.00€10mg472.00€25mg753.00€50mg1,017.00€100mg1,311.00€1mL*10mM (DMSO)434.00€PFI-2 hydrochloride
CAS:PFI-2 hydrochloride ((R)-PFI-2 hydrochloride) is a potent, highly selective, and cell-active inhibitor of the methyltransferase activity of SETD7 (IC50: 2 nM),Formula:C23H26ClF4N3O3SPurity:98.04% - 99.91%Color and Shape:SolidMolecular weight:535.98Ref: TM-T4583
1mg40.00€2mg51.00€5mg85.00€10mg117.00€25mg212.00€50mg378.00€100mg552.00€500mg1,169.00€1mL*10mM (DMSO)128.00€Daphnetin
CAS:Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),Formula:C9H6O4Purity:97.47% - 99.8%Color and Shape:SolidMolecular weight:178.14Ruxolitinib phosphate
CAS:Ruxolitinib phosphate (INCB18424 phosphate) is a JAK1/2 inhibitor with IC50 of 3.3 nM/2.8 nM. Cost-effective and quality-assured.Formula:C17H21N6O4PPurity:100% - 99.91%Color and Shape:SolidMolecular weight:404.36Ref: TM-T3043
1g615.00€5mg52.00€10mg65.00€25mg82.00€50mg97.00€100mg145.00€200mg227.00€500mg418.00€1mL*10mM (DMSO)59.00€
