Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Products of "Chromatin/Epigenetics"
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GSK126
CAS:GSK126 (GSK2816126A) is a excellently specific EZH2 methyltransferase inhibitor ( IC50=9.9 nM).Formula:C31H38N6O2Purity:98% - 99.67%Color and Shape:SolidMolecular weight:526.67Ref: TM-T2079
2mg44.00€5mg65.00€10mg88.00€25mg152.00€50mg227.00€100mg349.00€200mg455.00€1mL*10mM (DMSO)74.00€SMYD2-IN-1
CAS:SMYD2-IN-1 is an inhibitor of SMYD2 (IC50 of 4.45 nM).Formula:C25H25Cl2F2N7O2Purity:98%Color and Shape:SolidMolecular weight:564.41AT9283
CAS:AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).Formula:C19H23N7O2Purity:99.83% - 99.98%Color and Shape:SolidMolecular weight:381.43Ref: TM-T3068
1mg47.00€2mg60.00€5mg95.00€10mg170.00€25mg299.00€50mg499.00€100mg723.00€1mL*10mM (DMSO)97.00€CCT241736
CAS:CCT241736 is an orally bioavailable dual FLT3/Aurora kinase inhibitor that also inhibits clinically relevant FLT3-resistant mutants including FLT3-ITD and FLT3Formula:C22H23Cl2N7Purity:96.2% - 99.88%Color and Shape:SolidMolecular weight:456.37IHMT-EZH2-426
IHMT-EZH2-426 (compound 38) is a potent, covalent degrader of EZH2, demonstrating IC50 values of 1.3 nM for EZH2 wild-type, 1.2 nM for EZH2-A687V, and 1.7-3.5Formula:C31H35FN4O4SPurity:98%Color and Shape:SolidMolecular weight:578.7MS9715
MS9715 is a potent and selective NSD3-targeting PROTAC, designed by leveraging BI-9321, which targets the PWWP1 domain of NSD3, in conjunction with an E3 ligaseFormula:C58H74FN9O5SPurity:98%Color and Shape:SolidMolecular weight:1028.33GSK467
CAS:GSK467 is a potent and selective inhibitor of KDM5 (JARID1)(Ki : 10 nM).Formula:C17H13N5O2Purity:99.55%Color and Shape:SolidMolecular weight:319.32Pacritinib
CAS:Pacritinib (SB1518) (SB1518) is an effective and specific inhibitor of JAK2 and FLT3 (IC50: 23/22 nM, in cell-free assays).Formula:C28H32N4O3Purity:99.25% - 99.49%Color and Shape:SolidMolecular weight:472.58GSK778 hydrochloride
CAS:GSK778 hydrochloride is a selective BET BD1 bromodomain inhibitor, with IC50s ranging from 41 to 143 nM, effective in cancer models.Formula:C30H34ClN5O3Purity:97.45%Color and Shape:SolidMolecular weight:548.08Ref: TM-T9703L
1mg115.00€5mg249.00€10mg368.00€25mg562.00€50mg787.00€100mg1,054.00€1mL*10mM (DMSO)319.00€PBRM1-BD2-IN-7
CAS:PBRM1-BD2-IN-7, a PBRM1 bromodomain inhibitor with an IC50 of 0.29 μM, is used in cancer research.Formula:C16H15ClN2OPurity:99% - 99.86%Color and Shape:SoildMolecular weight:286.76Ref: TM-T60155
1mg115.00€5mg255.00€10mg375.00€25mg562.00€50mg792.00€100mg1,064.00€500mg2,147.00€1mL*10mM (DMSO)240.00€Upadacitinib
CAS:Upadacitinib (ABT-494), a selective JAK1 inhibitor, is researched for autoimmune diseases; IC50: 43 nM.Formula:C17H19F3N6OPurity:98.96% - 99.93%Color and Shape:SolidMolecular weight:380.37Ref: TM-T7503
1mg47.00€2mg62.00€5mg89.00€10mg130.00€25mg220.00€50mg306.00€100mg434.00€200mg662.00€500mg1,169.00€1mL*10mM (DMSO)48.00€BRD7-IN-1
CAS:BRD7-IN-1, a BI7273 derivative, forms PROTAC VZ185, targeting BRD7/9 with DC50s of 4.5/1.8 nM via VHL ligand linkage.Formula:C22H28Cl2N4O3Purity:98.95%Color and Shape:SolidMolecular weight:467.39OXF BD 02
CAS:OXF BD 02 is a potent and selective BRD4(1) inhibitor (IC50: 382 nM) with anticancer and anti-inflammatory activity.Formula:C18H17NO3Purity:98.25%Color and Shape:SolidMolecular weight:295.33LSD1-IN-24
CAS:LSD1-IN-24 is a selective and potent LSD1 inhibitor with an IC50 value of 0.247 μM.LSD1-IN-24 induces PD-L1 expression and enhances the T cell killing responseFormula:C18H20N2OSPurity:99.53%Color and Shape:SoildMolecular weight:312.43Ref: TM-T67871
1mg57.00€5mg120.00€10mg187.00€25mg374.00€50mg612.00€100mg938.00€500mg1,882.00€1mL*10mM (DMSO)133.00€BRD0639
CAS:BRD0639 is a first-in-class PRMT5-substrate interaction inhibitor for PBM-dependent PRMT5 activity studies.Formula:C21H22ClN5O4SPurity:99.85%Color and Shape:SolidMolecular weight:475.95EEDi-5285
CAS:EEDi-5285: potent EED inhibitor, orally active, IC50=0.2nM, targets EED protein, anti-cancer properties.Formula:C24H22FN5O3SPurity:100%Color and Shape:SolidMolecular weight:479.53(+)-JQ1 PA
CAS:(+)-JQ1 PA is a derivative of the Bromodomain and extra-terminal (BET) inhibitor JQ1(IC50 of 10.4 nM).Formula:C22H20ClN5OSPurity:98.36%Color and Shape:SolidMolecular weight:437.95Desidustat
CAS:Desidustat is an inhibitor of HIF hydroxylase.Formula:C16H16N2O6Purity:98%Color and Shape:SolidMolecular weight:332.31Ref: TM-T5176
1mg35.00€2mg52.00€5mg94.00€10mg167.00€25mg300.00€50mg516.00€100mg732.00€1ml*10 (DMSO)112.00€Histone Acetyltransferase Inhibitor II
CAS:Histone Acetyltransferase Inhibitor II is a selective and cell permeable inhibitor of p300 histone acetyltransferase(IC50 : 5 μM).with anti-acetylase activityFormula:C20H16Br2O3Purity:97.13%Color and Shape:SolidMolecular weight:464.15(R)-(-)-JQ1 Enantiomer
CAS:(R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1. (+)-JQ1 is a BET bromodomain inhibitor, acting on BRD4(1/2)(IC50 of 77 nM/33 nM in a cell-free assay)Formula:C23H25ClN4O2SPurity:99.38%Color and Shape:SolidMolecular weight:456.99
