Chromatin/Epigenetics
Chromatin/epigenetics inhibitors are compounds that modulate the structure and function of chromatin or interfere with epigenetic modifications, such as DNA methylation and histone modification. These inhibitors are essential tools for studying gene expression regulation and the role of epigenetics in diseases like cancer, neurological disorders, and developmental abnormalities. By targeting epigenetic processes, these inhibitors can alter gene expression patterns and offer new therapeutic avenues. At CymitQuimica, we provide a wide selection of high-quality chromatin/epigenetics inhibitors to support your research in molecular biology, genetics, and epigenetics.
Subcategories of "Chromatin/Epigenetics"
Products of "Chromatin/Epigenetics"
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PRMT5-IN-29
CAS:PRMT5-IN-29 is a potent, orally active inhibitor of PRMT5, exhibiting an IC50 value of 1.5 μM, showing promise for use in advanced cancer research [1].Formula:C18H20Cl3N5O5Purity:98%Color and Shape:SolidMolecular weight:492.74Palmatine
CAS:Palmatine, also known as Burasaine, inhibits dopamine production and may treat flavivirus, jaundice, dysentery, hypertension, and liver issues.Formula:C21H22NO4Purity:96.28% - 99.49%Color and Shape:SolidMolecular weight:352.4HIF-2α-IN-4
CAS:HIF-2a translation inhibitor is a compound used as a molecular building block.Formula:C9H9N3O4S2Purity:≥98%Color and Shape:SolidMolecular weight:287.32T-448
CAS:T-448 is a lysine-specific demethylase 1 inhibitor (IC50: 22 nM) that improves learning function in mice.T-448 can be used to study memory deficits.Formula:C19H22N4O3SPurity:97% - 98.63%Color and Shape:SolidMolecular weight:386.47SNDX-5613
CAS:Revumenib (SNDX-5613) is a potent and selective oral inhibitor of menin-KMT2A interaction.Cost-effective and quality-assured.Formula:C32H47FN6O4SPurity:99.12% - 99.12%Color and Shape:SolidMolecular weight:630.82Ref: TM-T12943
1mg73.00€2mg97.00€5mg160.00€10mg274.00€25mg542.00€50mg778.00€100mg1,074.00€1mL*10mM (DMSO)217.00€S2101
CAS:S 2101 is an inhibitor of lysine-specific demethylase 1 (LSD1)(IC50 of 0.99 μM, Ki of 0.61 μM and Kinact/Ki of 4560 M/s).Formula:C16H16ClF2NOPurity:98%Color and Shape:SolidMolecular weight:311.75PFI-3
CAS:PFI-3 is a selective chemical inhibitor for SMARCA (2/4) (Kd = 89 nM)and PBI (5) bromodomains which may result in the delay and prevention of breast cancer.Formula:C19H19N3O2Purity:99.71% - 99.94%Color and Shape:SolidMolecular weight:321.37Ref: TM-T6939
1mg38.00€2mg49.00€5mg78.00€10mg103.00€25mg210.00€50mg319.00€100mg474.00€1mL*10mM (DMSO)78.00€HDAC3-IN-T247
CAS:HDAC3-IN-T247 (HDAC3 inhibitor T247) is a histone deacetylase 3 (HDAC3) inhibitor with antiviral activity that inhibits the proliferation of cancer cells.Formula:C21H19N5OSPurity:98.11% - 98.94%Color and Shape:SolidMolecular weight:389.47Ref: TM-T24131
1mg92.00€5mg188.00€10mg311.00€25mg643.00€50mg914.00€100mg1,216.00€1mL*10mM (DMSO)215.00€Ifidancitinib
CAS:Ifidancitinib (ATI-50002) is a JAK kinase 1/3 inhibitor used to study autoimmune diseases.Formula:C20H18FN5O3Purity:98.05%Color and Shape:SolidMolecular weight:395.39O6BTG-C8-αGlu
CAS:O6BTG-C8-αGlu is an O6-methylguanine-DNA methyltransferase (MGMT) inhibitor with an IC50 of 0.45 μM. At a concentration of 0.1 μM, it fully inhibits MGMT in HeLaS3 cells and demonstrates no cytotoxicity even at prolonged high doses (up to 20 μM). This compound is suitable for research on MGMT-related cancers.Formula:C24H34BrN5O7SColor and Shape:SolidMolecular weight:616.525GNE-049
CAS:GNE-049 is a highly potent and selective inhibitor of CBP (IC50: 1.1 nM in TR-FRET assay).Formula:C27H32F2N6O2Color and Shape:SolidMolecular weight:510.58PBRM1-BD2-IN-2
CAS:PBRM1-BD2-IN-2 selectively inhibits PBRM1 with Kd 9.3μM & IC50 1.0μM, useful in cancer research.Formula:C14H9Cl2FN2OPurity:100%Color and Shape:SoildMolecular weight:311.14Ref: TM-T60156
1mg115.00€5mg255.00€10mg375.00€25mg562.00€50mg787.00€100mg1,074.00€500mg2,157.00€1mL*10mM (DMSO)245.00€JAK-IN-10
CAS:JAK-IN-10 is a JAK inhibitor. JAK-IN-10 can be used for the research of dry eye disorders.Formula:C20H18FN5O3SPurity:98.88%Color and Shape:SolidMolecular weight:427.45Ref: TM-T13571
1mg87.00€5mg177.00€10mg260.00€25mg429.00€50mg605.00€100mg815.00€500mg1,624.00€1mL*10mM (DMSO)188.00€WDR5-IN-6
CAS:WDR5-IN-6 is a WDR5 inhibitor targeting the WBM locus.WDR5-IN-6 is highly synergistic with OICR-9429, a WDR5 inhibitor that targets the WIN locus.WDR5-IN-6Formula:C13H8Cl2N2O2SPurity:99.69%Color and Shape:SoildMolecular weight:327.19PRMT3-IN-4
PRMT3-IN-4 (intermediate 15) is an inhibitor of Protein arginine methyltransferase 3 (PRMT3) and serves as the active control for SGC707. It can be utilized in the synthesis of PROTACs targeting PRMT3 and is applicable in research related to leukemia.Color and Shape:Odour SolidJAK kinase-IN-1
CAS:JAK kinase-IN-1 (Example 1) functions as a potent inhibitor targeting the JAK family, which includes TYK2, JAK1, JAK2, and JAK3, with IC50 values of 4.2 nM, 32Formula:C17H19F2N7OSPurity:98%Color and Shape:SolidMolecular weight:407.441-benzyl-2-ethyl-4,5,6,7-tetrahydro-1H-indol-4-one
CAS:1-benzyl-2-ethyl-4,5,6,7-tetrahydro-1H-indol-4-one is an inhibitor Bromodomain-containing protein 4 (human).Formula:C17H19NOPurity:99.08%Color and Shape:SolidMolecular weight:253.34Ref: TM-T8601
1mg88.00€5mg170.00€10mg259.00€25mg425.00€50mg598.00€100mg810.00€200mg1,074.00€1mL*10mM (DMSO)164.00€ITK inhibitor 2
CAS:ITK inhibitor 2 is a interleukin-2-inducible T-cell kinase (ITK) inhibitor , with an IC50 of 2 nM.Formula:C25H33N5O2Color and Shape:SolidMolecular weight:435.56UNC 669
CAS:UNC 669 is an effective and specific MBT (malignant brain tumor) inhibitor with IC50 of 4.2/3.1 uM for L3MBTL1/3.Formula:C15H20BrN3OPurity:97.38%Color and Shape:SolidMolecular weight:338.24Nicotinamide riboside
CAS:Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-Formula:C11H15N2O5Purity:98.61% - 99.58%Color and Shape:SolidMolecular weight:255.25
