DNA Methyltransferase
DNA methyltransferases (DNMTs) are enzymes that catalyze the addition of methyl groups to cytosine residues in DNA, leading to gene silencing. Aberrant DNA methylation is associated with various diseases, including cancer. DNMT inhibitors block the activity of these enzymes, leading to the reactivation of silenced genes and induction of apoptosis in cancer cells. DNMT inhibitors are widely used in epigenetic research and cancer therapy. At CymitQuimica, we provide a range of high-quality DNMT inhibitors to support your research in epigenetics, DNA methylation, and cancer biology.
Products of "DNA Methyltransferase"
Sort by
MC3343
CAS:MC3343, a DNMT1/3A inhibitor, affects tumor proliferation by blocking osteosarcoma cells in the G1 or G2/M phase and induces osteogenic differentiation.Formula:C27H23N7OPurity:99.73%Color and Shape:SolidMolecular weight:461.52Ref: TM-T203345
1mg185.00€5mg459.00€10mg657.00€25mg1,026.00€50mg1,415.00€100mg1,872.00€200mg2,555.00€DS79932728
CAS:DS79932728 is an orally active inhibitor of G9a and GLP, with IC50 values of 12.6 nM and 75.7 nM, respectively. It induces the production of γ-globin, thereby increasing fetal hemoglobin (HbF) levels. In cynomolgus monkey models, DS79932728 enhances the proportion of F-reticulocytes (F-rets) and shows good oral absorption characteristics.Formula:C19H25N3OColor and Shape:SolidMolecular weight:311.421Hinokitiol
CAS:Hinokitiol prevents UVB-caused cell death, boosts antioxidant activity, and hinders breast cancer growth.Formula:C10H12O2Purity:99.49% - 99.67%Color and Shape:SolidMolecular weight:164.2EPZ011989
CAS:EPZ011989: potent, selective oral EZH2 inhibitor, Ki < 3 nM, 15x more selective than EZH1, >3000x over other HMTases.Formula:C35H51N5O4Purity:98% - 99.81%Color and Shape:SolidMolecular weight:605.81UNC0638
CAS:UNC0638 inhibits G9a and GLP lysine methyltransferases with IC50 <15 nM and 19 nM, respectively, showing high selectivity.Formula:C30H47N5O2Purity:98.88% - 99.53%Color and Shape:SolidMolecular weight:509.73MM-102
CAS:MM-102 (HMTase Inhibitor IX) is a potent inhibitor of WDR5/MLL interaction with IC50 of 2.4 nM and Ki of less than 1 nM in a WDR5 binding assay.Cost-effective and quality-assured.Formula:C35H49F2N7O4Purity:98.77% - 99.08%Color and Shape:SolidMolecular weight:669.8Ref: TM-T6333
1mg39.00€2mg51.00€5mg105.00€10mg168.00€25mg351.00€50mg543.00€100mg777.00€1mL*10mM (DMSO)156.00€PF-06726304 acetate
CAS:PF-06726304 acetate is a selective inhibitor of EZH2, with robust antitumor growth activity.Formula:C24H25Cl2N3O5Purity:98%Color and Shape:SolidMolecular weight:506.38MIV-6R
CAS:MIV-6R inhibits Menin-MLL interaction (IC50: 56 nM) and can be used to study leukemia.Formula:C27H35N3OPurity:100.00% - 99.88%Color and Shape:SolidMolecular weight:417.59Benzoic acid, 3,4,5-trihydroxy-,(2R,3R)-3,4-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3-yl ester
CAS:Formula:C22H18O11Purity:98%Color and Shape:SolidMolecular weight:458.3717PRMT5-IN-29
CAS:PRMT5-IN-29 is a potent, orally active inhibitor of PRMT5, exhibiting an IC50 value of 1.5 μM, showing promise for use in advanced cancer research [1].Formula:C18H20Cl3N5O5Purity:98%Color and Shape:SolidMolecular weight:492.74
