Glucocorticoid Receptor
The glucocorticoid receptor (GR) is a nuclear hormone receptor that mediates the effects of glucocorticoids, a class of steroid hormones involved in the regulation of metabolism, immune response, and stress. Glucocorticoid receptor agonists and antagonists are widely used in the treatment of inflammatory and autoimmune diseases, as well as in cancer therapy. GR modulators are also important tools for studying the physiological and pathological roles of glucocorticoids. At CymitQuimica, we provide a wide range of high-quality glucocorticoid receptor modulators to support your research in endocrinology, immunology, and hormone regulation.
Products of "Glucocorticoid Receptor"
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Medrysone
CAS:Medrysone is a synthetic glucocorticoid for topical use with anti-inflammatory and anti-allergic effects, altering gene expression to reduce inflammation.Formula:C22H32O3Purity:97.72% - 99.91%Color and Shape:SolidMolecular weight:344.49Prednisolone hemisuccinate
CAS:Prednisolone hemisuccinate is a soluble glucocorticoid and cortisol exerts anti-inflammatory, immunosuppressive, and antiallergic by binding to GR receptor.Formula:C25H32O8Purity:99.96%Color and Shape:SolidMolecular weight:460.52Dexamethasone acetate
CAS:Dexamethasone acetate (NSC 39471) is a potent anti-inflammatory steroid, blocks NF-kB, and lacks salt-retention.Formula:C24H31FO6Purity:99.22% - 99.65%Color and Shape:White Or Almost White Crystalline PowderMolecular weight:434.5GSK9027
CAS:GSK9027, a nonsteroidal GR agonist, is a partial 2×GRE reporter gene activator, less potent than dexamethasone.Formula:C27H19F4N3O2SPurity:99.36%Color and Shape:SolidMolecular weight:525.52N-Demethyl Mifepristone
CAS:N-Demethyl Mifepristone (RU 42633), an active metabolite of Mifepristone, exhibits 61% of the affinity for the glucocorticoid receptor relative to Mifepristone'Formula:C28H33NO2Purity:98%Color and Shape:SolidMolecular weight:415.57Apararenone
CAS:Apararenone (MT-3995) is a receptor antagonist of mineralocorticoid receptor which can be used to treat non-alcoholic steatohepatitis and diabetic nephropathy.Formula:C17H17FN2O4SPurity:99.65%Color and Shape:SolidMolecular weight:364.3922-Hydroxy mifepristone
CAS:22-Hydroxy Mifepristone (RU 42698) is an orally active hydroxylated alcohol metabolite that exhibits both anti-progestational and anti-glucocorticoid activities. This compound contains an alkyne group and is capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAC) with azide-containing molecules. Furthermore, 22-Hydroxy Mifepristone demonstrates a relative binding affinity of 48% to the human glucocorticoid receptor.Formula:C29H35NO3Color and Shape:SolidMolecular weight:445.59Prednisolone acetate
Prednisolone acetate (Omnipred) is the acetate salt form of prednisolone, a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.Formula:C23H30O6Purity:98.26% - 98.85%Color and Shape:White Crystalline PowderMolecular weight:402.48Fluticasone furoate
CAS:Fluticasone furoate (Avamys), a potent, trifluorinated steroid with anti-inflammatory effects, treats allergic rhinitis.Formula:C27H29F3O6SPurity:99.58%Color and Shape:SolidMolecular weight:538.58Ref: TM-T21404
4g2,663.00€5mg35.00€10mg52.00€25mg92.00€50mg137.00€100mg187.00€200mg279.00€500mg472.00€1mL*10mM (DMSO)58.00€Mifepristone
CAS:Mifepristone (C-1073) is a Progestin Antagonist. The mechanism of action of mifepristone is as a Progestational Hormone Receptor Antagonist.Formula:C29H35NO2Purity:98.9% - ≥95%Color and Shape:Pale Yellow SolidMolecular weight:429.59Fluocinolone (Acetonide)
CAS:Fluocinolone Acetonide (Flucort-N) is a glucocorticoid derivative used topically in the treatment of various skin disorders.Formula:C24H30F2O6Purity:99.29% - 99.66%Color and Shape:Crystals From Acetone & Hexane SolidMolecular weight:452.49Miricorilant
CAS:Miricorilant (CORT 118335) is a glucocorticoid receptor modulator for the study of digestive and metabolic disorders.Formula:C24H23F3N2O2Purity:98.62%Color and Shape:SolidMolecular weight:428.45Fludrocortisone acetate
CAS:Fludrocortisone acetate (9α-Fludrocortisone acetate) , a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, andFormula:C23H31FO6Purity:96.92% - 98.03%Color and Shape:Crystalline SolidMolecular weight:422.49Dexamethasone palmitate
CAS:DXP, a lipophilic prodrug of Dexamethasone, has 47x less glucocorticoid receptor affinity; it's an agonist & anti-inflammatory.Formula:C38H59FO6Purity:98.08%Color and Shape:SolidMolecular weight:630.87Triamcinolone hexacetonide
CAS:Triamcinolone hexacetonide, an exogenous synthetic corticosteroid, is a GR agonist used in the study of auto-reactive pericarditis and diabetic macular edema.Formula:C30H41FO7Purity:99.57%Color and Shape:SolidMolecular weight:532.64Amcinonide
CAS:Amcinonide (CL-34699) is a Corticosteroid. The mechanism of action of amcinonide is as a Corticosteroid Hormone Receptor Agonist.Formula:C28H35FO7Purity:98.33% - 99.62%Color and Shape:SolidMolecular weight:502.57Budesonide
CAS:Budesonide (Pulmicort), an anti-inflammatory corticosteroid, has shown the effective glucocorticoid activitie and few mineralocorticoid activities. According to reports, Budesonide has extensively inhibitory effects against multiple cells types and mediators referred to allergic and nonallergic-mediated inflammatory. What's more, the anti-inflammatory action of budesonide has been revealed to contribute to the effectiveness of asthma.Formula:C25H34O6Purity:99.03% - 99.72%Color and Shape:Crystals SolidMolecular weight:430.53Cortisone acetate
CAS:Cortisone Acetate is a synthetic or semisynthetic analog of the naturally occurring cortisone hormone produced by the adrenal glands with anti-inflammatory andFormula:C23H30O6Purity:98.63% - 99.73%Color and Shape:SolidMolecular weight:402.48Corticosterone
CAS:Corticosterone (Kendall's compound B) is an adrenocortical steroid with salocorticoid and glucocorticoid activity that is orally active.Formula:C21H30O4Purity:97.25% - ≥95%Color and Shape:SolidMolecular weight:346.46Prednisolone
CAS:Prednisolone (Hydroretrocortine) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.Formula:C21H28O5Purity:99.59% - 99.85%Color and Shape:Crystals SolidMolecular weight:360.44
