TLR
Toll-like receptors (TLRs) are a class of proteins that play a critical role in the innate immune system by recognizing pathogen-associated molecular patterns (PAMPs) and initiating immune responses. TLRs are involved in detecting a wide range of pathogens, including bacteria, viruses, and fungi, and are essential for the activation of inflammatory signaling pathways. Dysregulation of TLR signaling is associated with chronic inflammatory diseases, autoimmune disorders, and cancer. At CymitQuimica, we offer a variety of high-quality TLR modulators to support your research in innate immunity, inflammation, and infectious disease.
Products of "TLR"
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CU-CPT22
CAS:CU-CPT22: first TLR1/2 complex probe, binds at TLR1/2 interface (IC50=0.58μM), inhibits Pam3CSK4 binding (Ki=0.41μM).Formula:C19H22O7Purity:98.66%Color and Shape:SolidMolecular weight:362.37Ref: TM-T15020
1mg52.00€2mg70.00€5mg99.00€10mg168.00€25mg313.00€50mg469.00€100mg682.00€200mg938.00€1mL*10mM (DMSO)114.00€BMS-905
CAS:BMS-905 is a potent dual inhibitors of TLR7 and TLR8 with good selectivity against TLR9 and other family members.Formula:C23H29N3Purity:99.85%Color and Shape:SoildMolecular weight:347.5SM-324405
CAS:SM-324405 is an agonist of TLR7.Formula:C19H23N5O4Purity:97.83%Color and Shape:SolidMolecular weight:385.42Ref: TM-T7860
1mg37.00€5mg78.00€10mg113.00€25mg202.00€50mg324.00€100mg462.00€200mg645.00€1mL*10mM (DMSO)87.00€AXC-715 trihydrochloride
CAS:AXC-715 trihydrochloride is a TLR7/8 agonist used to make PD-L1 adjuvanted antibody immunocouplings.Formula:C18H28Cl3N5Purity:99.74%Color and Shape:SolidMolecular weight:420.81Gardiquimod
CAS:Gardiquimod, an imidazoquinoline TLR7 agonist, inhibits HIV-1 in macrophages and PBMCs under 10μM.Formula:C17H23N5OPurity:98.02% - 99.47%Color and Shape:SolidMolecular weight:313.4CU-CPT17e
CAS:CU-CPT17e is a potent agonist of TLR(TLR3, TLR8, and TLR9).Formula:C27H24N2O8Purity:98.49%Color and Shape:SolidMolecular weight:504.49Cholesterol oxidase
CAS:Cholesterol oxidase catalyzes the oxidation and isomerization of cholesterol. ChOx competitively inhibits TLR2 enhance ROS production by macrophages.Color and Shape:SolidE6446
CAS:E6446 inhibits Toll-like receptor (TLR)7 and 9 signaling.Formula:C27H35N3O3Purity:98.72%Color and Shape:SolidMolecular weight:449.59Rabeximod
CAS:Rabeximod, an immunomodulator, eases autoimmune diseases, inhibits arthritis, and aids brain recovery post-injury by blocking inflammation.Formula:C22H24ClN5OPurity:100%Color and Shape:SolidMolecular weight:409.91Tomaralimab
CAS:Tomaralimab (OPN-305) is a humanized IgG4 monoclonal antibody targeting TLR2. Tomarlimab is used to study myelodysplastic syndromes (MDS).Purity:> 95% - SDS-PAGE:95% SEC-HPLC:99.99%Color and Shape:LiquidMolecular weight:145.32 kDaTLR7/8 agonist 1 dihydrochloride
CAS:TLR7/8 agonist 1 dihydrochloride (TLR7/8 agonist-5d) is a TLR7/8 agonist which shows prominent immunostimulatory activities.Formula:C22H27Cl2N5Purity:98.33%Color and Shape:SolidMolecular weight:432.39MD2-IN-1
CAS:MD2-IN-1 is a Myeloid differentiation protein 2 (MD2) inhibitor with a KD of 189 μM for the recombinant human MD2 (rhMD2).Formula:C20H22O6Purity:99.87%Color and Shape:SolidMolecular weight:358.39C29
CAS:C29 inhibits TLR2/1 and TLR2/6 in human cells, but only TLR2/1 in mouse macrophages.Formula:C16H15NO4Purity:96.34% - 97.37%Color and Shape:SolidMolecular weight:285.29TLR7 agonist 2
CAS:TLR7 agonist 2 (TLR7-IN-1) is a specific and effective Toll-like Receptor 7 (TLR7) agonist (LEC=0.4 μM).Formula:C17H16N6O2Purity:99.33%Color and Shape:SolidMolecular weight:336.35Ref: TM-T4258
1mg157.00€2mg240.00€5mg495.00€10mg717.00€25mg1,111.00€50mg1,501.00€100mg2,023.00€1mL*10mM (DMSO)365.00€Desethyl chloroquine diphosphate
CAS:Desethyl chloroquine diphosphate is the active metabolite of Desethylchloroquine, an inhibitor of TLRs with antiplasmodial activity and inhibition of autophagy.Formula:C16H28ClN3O8P2Purity:99.72%Color and Shape:SolidMolecular weight:487.81TLR7/8-IN-1
CAS:TLR7/8-IN-1, a crystalline TLR7/TLR8 inhibitor, is a valuable compound for autoimmune disease research.Cost-effective and quality-assured.Formula:C29H40N8O2Purity:99.83%Color and Shape:SolidMolecular weight:532.68PF-4878691
CAS:PF-4878691 (3M-852A) is an effective and selective Toll-like receptor 7 agonists modelled. It is used to dissociate its antiviral and inflammatory activities.Formula:C17H23N5O2SPurity:98.43%Color and Shape:SolidMolecular weight:361.46Ref: TM-T16506
1mg48.00€5mg144.00€10mg235.00€25mg512.00€50mg847.00€100mg1,378.00€1mL*10mM (DMSO)159.00€TLR7/8/9-IN-1
CAS:TLR7/8/9-IN-1 is a potent inhibitor of Toll-like receptors 7/8/9 (TLR7/8/9) with an IC50 of 43 nM.Formula:C27H37N3O2Purity:98.31%Color and Shape:SolidMolecular weight:435.6Ref: TM-T39669
1mg52.00€2mg73.00€5mg117.00€10mg188.00€25mg306.00€50mg449.00€100mg610.00€200mg872.00€1mL*10mM (DMSO)170.00€AN3485 Hydrochloride
CAS:AN3485 Hydrochloride is an anti-inflammatory agent and a TLRs inhibitor, reducing ear swelling induced by PMA.Formula:C14H14BCl2NO3Purity:99.76%Color and Shape:SolidMolecular weight:325.98ODN 1668
CAS:ODN 1668 is an immunostimulatory class B CpG oligodeoxynucleotide (ODN), used as an agonist for TLR9, and upregulates the level of IgM.Color and Shape:SolidMolecular weight:6364.1
