MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
Products of "MAPK"
Sort by
Omtriptolide
CAS:Omtriptolide, triptolide purified from the Chinese herb, is a water-soluble derivative prodrug.Formula:C24H28O9Purity:98%Color and Shape:SolidMolecular weight:460.479p38α inhibitor 4
CAS:p38α inhibitor 4 is a selective MAPK p38α inhibitor, which is used to study diabetes, pain and chronic inflammation.Formula:C14H7F6N3OPurity:99.79%Color and Shape:SolidMolecular weight:347.215AZD7624
CAS:AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.Formula:C27H30FN5O3Purity:99.37%Color and Shape:SolidMolecular weight:491.56Ref: TM-T14381
1mg73.00€5mg160.00€10mg250.00€25mg507.00€50mg737.00€100mg1,026.00€1mL*10mM (DMSO)170.00€MK2-IN-3
CAS:MK2-IN-3 is a potent MK-2 inhibitor, cell-permeable, for rheumatoid arthritis treatment.Formula:C21H16N4OPurity:99.01%Color and Shape:SolidMolecular weight:340.38Ref: TM-T9034
1mg39.00€5mg84.00€10mg120.00€25mg255.00€50mg375.00€100mg535.00€200mg728.00€1mL*10mM (DMSO)87.00€OVA-E1 peptide TFA
CAS:OVA-E1 peptide TFA activates the p38 and JNK cascades similarly in mutant and wild-type thymocytes.Formula:C49H77F3N10O16Purity:98%Color and Shape:SolidMolecular weight:1119.19KRAS inhibitor-32
CAS:KRAS inhibitor-32 (compound 139A) is a KRAS inhibitor utilized in cancer research.Formula:C29H35FN10OS2Color and Shape:SolidMolecular weight:622.78Rupestonic acid
CAS:Rupestonic acid is a compound in Artemisia rupestris L., a well-known traditional Uighur medicine for the treatment of colds.Formula:C15H20O3Purity:98.07%Color and Shape:SolidMolecular weight:248.32PF-4708671
CAS:PF-4708671 is a cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) .In cell-free assays, PF-4708671 is potent for S6K1(Ki50=20 nM, IC50=160 nM).Formula:C19H21F3N6Purity:99.48% - 99.67%Color and Shape:SolidMolecular weight:390.41Glycinexylidide
CAS:Glycinexylidide (GX), the active metabolite of the local anesthetic Lidocaine, exhibits properties significant in inhibiting sodium channels with complexFormula:C10H14N2OPurity:98%Color and Shape:SolidMolecular weight:178.23Enniatin B
CAS:Enniatins B decreases the activation of ERK (p44/p42).Formula:C33H57N3O9Purity:98%Color and Shape:SolidMolecular weight:639.831Lyoniresinol
CAS:Lyoniresinol, a lignan from Tarenna attenuata, has antioxidant and anti-melanogenic properties, with an IC50 of 82.4 μM; tastes bitter.Formula:C22H28O8Purity:98%Color and Shape:SolidMolecular weight:420.45MBP MAPK Substrate acetate
MBP MAPK Substrate acetate can be used as an exogenous substrate for MAPK.Formula:C41H74N18O13Purity:99.71%Color and Shape:SolidMolecular weight:1026.56827Ref: TM-T38796L
1mg158.00€2mg212.00€5mg300.00€10mg434.00€25mg658.00€50mg905.00€100mg1,206.00€200mg1,634.00€Corynoxeine
CAS:Corynoxeine inhibits ERK1/2, curbs VSMC growth induced by PDGF-BB, and may prevent vascular diseases and restenosis post-angioplasty.Formula:C22H26N2O4Purity:98.61% - 99.73%Color and Shape:SolidMolecular weight:382.45Meranzin hydrate
CAS:Meranzin hydrate acts as an antidepressant and aids digestion, targeting α2-adrenoceptors and AMPA receptors, hastened by BDNF and ERK1/2 modulation.Formula:C15H18O5Purity:99.49%Color and Shape:SolidMolecular weight:278.3Chrysoeriol
CAS:Chrysoeriol has antioxidant, antiinflammatory, antitumor, antimicrobial, antiviral, and free radical scavenging activities, it also shows selectiveFormula:C16H12O6Purity:97.32%Color and Shape:SolidMolecular weight:300.26Ref: TM-TN1490
1mg48.00€5mg111.00€10mg180.00€25mg359.00€50mg532.00€100mg757.00€1mL*10mM (DMSO)120.00€Adagrasib
CAS:View and buy Adagrasib (MRTX849) from TargetMol.MRTX849 is a potent, selective and covalent KRASG12C inhibitor with potential antineoplastic activity. Cited in 2 publications.Formula:C32H35ClFN7O2Purity:99.10% - 99.9%Color and Shape:SolidMolecular weight:604.12Rubrofusarin gentiobioside
CAS:Rubrofusarin gentiobioside (Rubrofusarin-6-O-beta-D-gentiobioside) decreases the expression of TGF-beta1 and fibronectin and NF-kappaB DNA binding activity.Formula:C27H32O15Purity:99.75% - 99.91%Color and Shape:SolidMolecular weight:596.53Ref: TM-TN2165
1mg54.00€5mg115.00€10mg168.00€25mg284.00€50mg411.00€100mgTo inquire1mL*10mM (DMSO)170.00€LUNA18
CAS:LUNA18 is an orally active inhibitor targeting KRAS, exhibiting potent activity with an IC50 value of less than 2 nM against the KRAS G12D-SOS mutation.Formula:C73H105F5N12O12Purity:98%Color and Shape:SolidMolecular weight:1437.68magnolin
CAS:Magnolin reduces the renal oxidative stress, suppresses caspase-3 activity, and increases Bcl-2 expression in vivo and in vitro.Formula:C23H28O7Purity:98% - 99.77%Color and Shape:SolidMolecular weight:416.46TAK-632
CAS:TAK-632 is a potent pan-Raf inhibitor.Formula:C27H18F4N4O3SPurity:98% - 98.92%Color and Shape:SolidMolecular weight:554.52
