Ras
Ras proteins are small GTPases that act as molecular switches in the MAPK signaling pathway, controlling cell growth, differentiation, and survival. Activated Ras initiates a signaling cascade that includes Raf, MEK, and ERK, leading to various cellular responses. Mutations in Ras genes are common in cancers, making Ras an important focus of cancer research. At CymitQuimica, we offer a range of Ras modulators to support your research in cancer biology, signal transduction, and therapeutic development.
Products of "Ras"
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K-Ras(G12C) inhibitor 9
CAS:K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C).Formula:C16H21ClIN3O4SPurity:97.33% - 97.45%Color and Shape:SolidMolecular weight:513.78Ref: TM-T6556
1mg52.00€2mg74.00€5mg123.00€10mg183.00€25mg378.00€50mg547.00€100mg750.00€1mL*10mM (DMSO)183.00€KRAS G12C inhibitor 13
CAS:KRAS G12C inhibitor 13 is a KRAS G12C inhibitor .Formula:C40H46F3N7O4Purity:98%Color and Shape:SolidMolecular weight:745.83Pan-RAS-IN-7
CAS:Pan-RAS-IN-7 (Compound D101) is a broad-spectrum RAS inhibitor used in the synthesis of antibody-drug conjugates (ADCs). It is also applicable in cancer research.Formula:C59H76N8O8Color and Shape:SolidMolecular weight:1025.28Ketoconazole
CAS:Ketoconazole (R-41400), a CYP3A4 inhibitor, is an imidazole anti-fungal agent.Formula:C26H28Cl2N4O4Purity:99.53% - 99.62%Color and Shape:Crystals From 4-Methylpentanone SolidMolecular weight:531.43KRAS inhibitor-9
CAS:KRAS inhibitor-9 (DUN09716) hinders GTP-KRAS formation, with a Kd of 92 μM, causes G2/M arrest, and induces apoptosis in mutated NSC-LC cells.Formula:C13H9ClN2S2Purity:99.66%Color and Shape:SolidMolecular weight:292.81Ref: TM-T8756
1mg60.00€2mg86.00€5mg119.00€10mg188.00€25mg354.00€50mg512.00€100mg655.00€1mL*10mM (DMSO)143.00€KRAS G12C inhibitor 60
KRAS G12C Inhibitor 60 (compound 23), a selective inhibitor targeting the Kras-G12C mutation, is utilized in the investigation of lung, colorectal, andFormula:C31H30F5N7O2Purity:98%Color and Shape:SolidMolecular weight:627.61KRASG12C IN-14
KRASG12C IN-14 (compound 15), a potent inhibitor specifically designed for the KRAS G12C mutation, exhibits impressive efficacy in impeding CYPA-dependent KRAS-BRAF interaction and ERK phosphorylation in NCI-H358 cells, both with an IC 50 of 0.002 μM.Formula:C51H65F4N9O9S2Color and Shape:SolidMolecular weight:1088.24SOS1/KRAS-IN-1
CAS:SOS1/KRAS-IN-1 (Compound 2) serves as an inhibitor of SOS1/KRAS, with potential application in the study of diseases mediated by SOS1/KRAS [1].Formula:C24H26F3N5OPurity:98%Color and Shape:SolidMolecular weight:457.49Eicosapentaenoic Acid
CAS:Eicosapentaenoic Acid (EPA) is a ω-3 fatty acid abundantly available in marine organisms.Formula:C20H30O2Purity:96.20%Color and Shape:LiquidMolecular weight:302.45Oncrasin-1
CAS:Oncrasin 1 is a potent inhibitor of anticancer that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrationsFormula:C16H12ClNOPurity:99.75%Color and Shape:SolidMolecular weight:269.73(R)-BI-2852
CAS:(R)-5-hydroxy isoindolin-1-one is an RAS protein inhibitor with antiproliferative and antitumor properties.Formula:C31H28N6O2Purity:97.78%Color and Shape:SoildMolecular weight:516.59MLS-573151
CAS:MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM).Formula:C21H19N3O2SPurity:98.80%Color and Shape:SolidMolecular weight:377.46Ref: TM-T22106
2mg35.00€5mg52.00€10mg90.00€25mg170.00€50mg259.00€100mg383.00€200mg545.00€1mL*10mM (DMSO)58.00€CASIN
CAS:CASIN (Pirl1-related Compound 2) is a specific inhibitor of GTPase Cdc42 (IC50: 2 uM).Formula:C20H22N2OPurity:100% - 99.86%Color and Shape:SolidMolecular weight:306.4Ref: TM-T3971
1mg38.00€2mg49.00€5mg74.00€10mg120.00€25mg188.00€50mg283.00€100mg435.00€500mg938.00€1mL*10mM (DMSO)74.00€Sotorasib
CAS:Sotorasib (AMG-510) is an orally active and selective covalent inhibitor of KRAS G12C.Formula:C30H30F2N6O3Purity:98% - 99.89%Color and Shape:SolidMolecular weight:560.59Ref: TM-T8684
1g1,359.00€1mg37.00€2mg52.00€5mg79.00€10mg126.00€25mg225.00€50mg374.00€100mg459.00€500mg1,026.00€1mL*10mM (DMSO)87.00€CID-1067700
CAS:CID-1067700 is one of the first identified competitive inhibitors of nucleotide binding by Ras-related GTPases(Rab7 with a Ki of 13 nM).Formula:C18H18N2O4S2Purity:99.46%Color and Shape:SolidMolecular weight:390.48Ref: TM-T7558
1mg35.00€2mg52.00€5mg74.00€10mg111.00€25mg188.00€50mg246.00€100mg319.00€1mL*10mM (DMSO)82.00€KRAS G12D modulator-1
CAS:KRAS G12D modulator-1 (compound 6), a potent modulator of KRAS G12D, exhibits IC50 values ranging from 1-10 μM against NEA-G12D, PPI-G12D, and p ERK-AGS, and isFormula:C30H36FN5O4Purity:98%Color and Shape:SolidMolecular weight:549.64RBC10
CAS:RBC10 inhibits the binding of Ral to its effector RALBP1, as well as inhibiting Ral-mediated cell spreading of murine embryonic fibroblasts and anchorage-Formula:C24H25ClN2O2Purity:98.38%Color and Shape:SolidMolecular weight:408.92Ref: TM-T24706
1mg34.00€2mg52.00€5mg80.00€10mg116.00€25mg259.00€50mg374.00€100mg545.00€200mg740.00€1mL*10mM (DMSO)86.00€Rac1-IN-3
CAS:Rac1-IN-3 (Compound 2) is a Rac1 inhibitor exhibiting an inhibitory concentration 50 (IC50) of 46.1 μM [1].Formula:C21H23N7O2Purity:98%Color and Shape:SolidMolecular weight:405.45Antineoplaston A10
CAS:Antineoplaston A10 (NSC-648539) is a Ras inhibitor potentially for the treatment of glioma, lymphoma, astrocytoma and breast cancer.Formula:C13H14N2O3Purity:99.42%Color and Shape:SolidMolecular weight:246.26Ref: TM-T7131
2mg47.00€5mg71.00€10mg108.00€25mg205.00€50mg311.00€100mg449.00€200mg628.00€1mL*10mM (DMSO)78.00€KRAS inhibitor-38
CAS:KRAS Inhibitor-38 (Example 18) is a potent inhibitor capable of effectively suppressing the activity of KRAS G12C, KRAS G12D, and KRAS G12V in vivo.Formula:C53H68ClF2N9O8SColor and Shape:SolidMolecular weight:1064.68XMU-MP-9
CAS:XMU-MP-9, a bifunctional compound, targets the C2 domain of Nedd4-1 and the allosteric site of K-Ras. It enhances the interaction and induces conformational changes within the Nedd4-1/K-Ras complex. Furthermore, XMU-MP-9 facilitates the ubiquitination and degradation of various K-Ras mutants and inhibits the proliferation of cells with these mutants. This compound is useful in cancer research.Formula:C19H13ClFN3OSColor and Shape:SolidMolecular weight:385.84KRAS G12C inhibitor 14
CAS:KRAS G12C inhibitor 14 is a potent KRAS G12C inhibitor with an IC 50 of 18 nM [1].Formula:C24H19ClF2N4O3Purity:98%Color and Shape:SolidMolecular weight:484.88MCP110
CAS:MCP110 is an inhibitor of the interaction of Ras with Raf-1 and can be used in studies about the treatment of human tumors.Formula:C33H36N2O3Purity:97.18%Color and Shape:OilMolecular weight:508.65Ref: TM-T24437
1mg37.00€5mg97.00€10mg169.00€25mg291.00€50mg423.00€100mg562.00€500mg1,121.00€1mL*10mM (DMSO)108.00€EHT 1864 2HCl
CAS:EHT 1864 (EHT 1864 2HCl) is a Rac family GTPase inhibitor that blocks activation by direct binding to Rac1, Rac1b, Rac2, and Rac3. Cost effective and quality assured.Formula:C25H29Cl2F3N2O4SPurity:98.39% - 99.42%Color and Shape:SolidMolecular weight:581.47Ref: TM-T6483
1mg47.00€5mg92.00€10mg136.00€25mg259.00€50mg472.00€100mg677.00€200mg934.00€1mL*10mM (DMSO)107.00€(E/Z)-ZINC09659342
CAS:(E/Z)-ZINC09659342 is an inhibitor of Lbc-Rho A interaction.Formula:C23H15F3N2O4Purity:95.83%Color and Shape:SolidMolecular weight:440.37Ref: TM-T9986
1mg66.00€5mg145.00€10mg221.00€25mg378.00€50mg533.00€100mg718.00€200mg938.00€1mL*10mM (DMSO)160.00€(Rac)-Antineoplaston A10
CAS:Antineoplaston A10 is the first identified human antineoplaston, naturally occurring with anti-proliferative properties.Formula:C13H14N2O3Purity:98.41%Color and Shape:SolidMolecular weight:246.26Ref: TM-T5379
1mg40.00€5mg88.00€10mg129.00€25mg210.00€50mg311.00€100mg449.00€200mg627.00€1mL*10mM (DMSO)95.00€AZD0022
CAS:AZD0022 is a selective and orally active KRAS G12D inhibitor that displays exposure-dependent pRSK inhibition in a GP2D xenograft model.Formula:C34H30F4N6OColor and Shape:SoildMolecular weight:614.64ML-097
CAS:ML-097 (CID-2160985) is a pan activator of Ras-related GTPasesFormula:C14H11BrO3Purity:99.12%Color and Shape:SolidMolecular weight:307.139Ref: TM-T21970
5mg65.00€10mg95.00€25mg140.00€50mg202.00€100mg303.00€500mg725.00€1mL*10mM (DMSO)71.00€MRTF-A-IN-2
MRTF-A-IN-2 (compound 16) is an inhibitor of MRTF-A. It effectively suppresses cell proliferation and induces senescence in HCC cells.Color and Shape:Odour SolidKRAS G12C inhibitor 59
CAS:KRAS G12C Inhibitor 59 is a compound with anticancer properties.Formula:C32H39F6N7O5Purity:98%Color and Shape:SolidMolecular weight:715.69K-Ras-IN-1
CAS:K-Ras-IN-1 is a K-Ras inhibitor.Formula:C11H13NOSPurity:98.72%Color and Shape:SolidMolecular weight:207.29Ref: TM-T5469
2mg46.00€5mg70.00€10mg101.00€25mg182.00€50mg284.00€100mg424.00€200mg588.00€1mL*10mM (DMSO)77.00€Rhosin hydrochloride
CAS:Rhosin hydrochloride is a specific inhibitor of the RhoA subfamily Rho GTPases.Cost-effective and quality-assured.Formula:C20H20Cl2N6OPurity:97.33% - 98.92%Color and Shape:SolidMolecular weight:431.318Ref: TM-T16745
1mg159.00€2mg217.00€5mg329.00€10mg472.00€25mg753.00€50mg1,026.00€100mg1,378.00€1mL*10mM (DMSO)363.00€EHop-016
CAS:EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.Formula:C25H30N6OPurity:100% - 99.86%Color and Shape:SolidMolecular weight:430.55Ref: TM-T2427
5mg48.00€10mg73.00€25mg127.00€50mg213.00€100mg334.00€200mg492.00€500mg787.00€1mL*10mM (DMSO)52.00€KRAS inhibitor-33
KRAS inhibitor-33 (compound 115a) is a pyrido[2,3-d]pyrimidine derivative that serves as an effective inhibitor of KRAS, exhibiting an IC50 value of ≤ 100nM.Formula:C33H39ClF2N6O3Color and Shape:SolidMolecular weight:641.15
