Ras
Ras proteins are small GTPases that act as molecular switches in the MAPK signaling pathway, controlling cell growth, differentiation, and survival. Activated Ras initiates a signaling cascade that includes Raf, MEK, and ERK, leading to various cellular responses. Mutations in Ras genes are common in cancers, making Ras an important focus of cancer research. At CymitQuimica, we offer a range of Ras modulators to support your research in cancer biology, signal transduction, and therapeutic development.
Products of "Ras"
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KRAS G12C inhibitor 17
CAS:KRAS G12C inhibitor 17 is a potent KRAS G12C inhibitor.Formula:C24H20ClF2N3O3Purity:98%Color and Shape:SolidMolecular weight:471.88APS6-45
CAS:APS6-45 inhibits RAS/MAPK signaling and exhibits anti-tumor activity.Formula:C23H16F8N4O3Purity:99.39%Color and Shape:SolidMolecular weight:548.39Ref: TM-T8843
2mg39.00€5mg88.00€10mg127.00€25mg250.00€50mg401.00€100mg615.00€200mg830.00€1mL*10mM (DMSO)97.00€ML-099
CAS:ML-099 is a pan Ras-related GTPases activator that activates Rac1, Ras, GTP-binding protein (Rab7), Rab2A and cell division cycle 42.Formula:C14H13NO2SPurity:99.48%Color and Shape:SolidMolecular weight:259.32Ref: TM-T22991
1mg48.00€2mg64.00€5mg96.00€10mg153.00€25mg305.00€50mg487.00€100mg710.00€1mL*10mM (DMSO)94.00€KRas G12C inhibitor 2
CAS:KRas G12C inhibitor 2 is a compound that inhibits KRas G12C.Formula:C32H37N7O3Purity:98%Color and Shape:SolidMolecular weight:567.68SCH54292
CAS:SCH-54292 is a GDP exchange inhibitor.Formula:C24H28N2O9SPurity:95.65%Color and Shape:SolidMolecular weight:520.55pan-KRAS-IN-4
CAS:Pan-KRAS-IN-4 (compound 5) is a potent KRAS inhibitor, demonstrating IC50 values of 0.37 nM for Kras G12C and 0.19 nM for Kras G12V [1].Formula:C36H34F2N6O3Purity:98%Color and Shape:SolidMolecular weight:636.69KRas G12C inhibitor 1
CAS:KRas G12C inhibitor 1 is a compound that inhibits KRas G12C.Formula:C31H38N6O3Purity:98%Color and Shape:SolidMolecular weight:542.67Salirasib
CAS:Salirasib: Competitive PPMTase inhibitor, blocks Ras methylation, potential cancer treatment, Ki=2.6 μM.Formula:C22H30O2SPurity:99.45%Color and Shape:SolidMolecular weight:358.54Ref: TM-T6163
5mg35.00€10mg52.00€25mg96.00€50mg159.00€100mg221.00€200mg364.00€500mg597.00€1mL*10mM (DMSO)59.00€TH-Z827
CAS:TH-Z827 is a mutant-selective inhibitor targeting KRAS(G12D) with an IC50 of 2.4 μM, demonstrating specificity by not binding to KRAS(WT) or KRAS(G12C).Formula:C30H38N6OPurity:98%Color and Shape:SolidMolecular weight:498.66KRAS inhibitor-6
CAS:KRAS inhibitor-6 is a potent KRAS G12C inhibitor.Formula:C27H30ClF2N5O3Purity:98%Color and Shape:SolidMolecular weight:546.01KRAS G12C inhibitor 58
CAS:KRAS G12C inhibitor 58 is utilized in cancer research as an inhibitor of the KRAS G12C mutation [1].Formula:C51H64ClF4N9O8SPurity:98%Color and Shape:SolidMolecular weight:1074.62Lonafarnib
CAS:Lonafarnib (Sch66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 nM).Formula:C27H31Br2ClN4O2Purity:98% - 99.04%Color and Shape:SolidMolecular weight:638.82KRAS G12C inhibitor 15
CAS:KRAS G12C inhibitor 15 is a potent KRAS G12C inhibitor .Formula:C25H21ClF2N4O3Purity:98%Color and Shape:SolidMolecular weight:498.91ASP2453
CAS:ASP2453 is a potent, selective and covalent inhibitor of KRAS G12C.Formula:C40H48F3N7O4Purity:96.57%Color and Shape:SolidMolecular weight:747.85pan-KRAS-IN-2
CAS:Pan-KRAS-IN-2 (compound 6) is a broad-spectrum KRAS inhibitor exhibiting potent activity with IC50 values of ≤10 nM against KRAS wild type and its mutants (G12DFormula:C34H34F2N4O3Purity:98%Color and Shape:SolidMolecular weight:584.66MRTX1133
CAS:View and buy MRTX1133 from TargetMol.MRTX1133 is a potent, selective, and noncovalent inhibitor of KRAS G12D.Formula:C33H31F3N6O2Purity:97.39% - 99.10%Color and Shape:SolidMolecular weight:600.63Ref: TM-T9303
1mg187.00€5mg399.00€10mg612.00€25mg944.00€50mg1,320.00€100mg1,730.00€200mg2,337.00€1mL*10mM (DMSO)530.00€ACBI3
CAS:ACBI3 is a selective pan-KRAS degrader with anticancer activity that degrades oncogenic KRAS. ACBI3 inhibits the growth of most cancer cell lines driven by KRAS mutations.Formula:C50H62N14O6S2Purity:99.24%Color and Shape:SolidMolecular weight:1019.25Sevelamer Carbonate
CAS:Sevelamer carbonate, a non-absorbed polymer, binds phosphate with carbonate instead of chloride.Formula:(C3H7N·C3H5ClO)x·xCH2O3Purity:98%Color and Shape:SolidMolecular weight:211.64RBC8
CAS:RBC8 is a specific GTPases RalA/RalB inhibitor by inhibiting the binding of Ral to its effector RALBP1, no inhibition on the GTPases RhoA and Ras.Formula:C25H20N4O3Purity:98.44% - 99.81%Color and Shape:SolidMolecular weight:424.45Ref: TM-T6634
1mg48.00€5mg92.00€10mg156.00€25mg298.00€50mg472.00€100mg687.00€200mg938.00€1mL*10mM (DMSO)97.00€Deltarasin
CAS:Deltarasin is a small molecular inhibitor of KRAS-PDEδ interaction with Kd of 38 nM for binding to purified PDEδ.Formula:C40H37N5OPurity:99.06%Color and Shape:SolidMolecular weight:603.75
