Ras
Ras proteins are small GTPases that act as molecular switches in the MAPK signaling pathway, controlling cell growth, differentiation, and survival. Activated Ras initiates a signaling cascade that includes Raf, MEK, and ERK, leading to various cellular responses. Mutations in Ras genes are common in cancers, making Ras an important focus of cancer research. At CymitQuimica, we offer a range of Ras modulators to support your research in cancer biology, signal transduction, and therapeutic development.
Products of "Ras"
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XMU-MP-9
CAS:XMU-MP-9, a bifunctional compound, targets the C2 domain of Nedd4-1 and the allosteric site of K-Ras. It enhances the interaction and induces conformational changes within the Nedd4-1/K-Ras complex. Furthermore, XMU-MP-9 facilitates the ubiquitination and degradation of various K-Ras mutants and inhibits the proliferation of cells with these mutants. This compound is useful in cancer research.Formula:C19H13ClFN3OSColor and Shape:SolidMolecular weight:385.84KRAS G12C inhibitor 14
CAS:KRAS G12C inhibitor 14 is a potent KRAS G12C inhibitor with an IC 50 of 18 nM [1].Formula:C24H19ClF2N4O3Purity:98%Color and Shape:SolidMolecular weight:484.88MCP110
CAS:MCP110 is an inhibitor of the interaction of Ras with Raf-1 and can be used in studies about the treatment of human tumors.Formula:C33H36N2O3Purity:97.18%Color and Shape:OilMolecular weight:508.65Ref: TM-T24437
1mg37.00€5mg97.00€10mg169.00€25mg291.00€50mg423.00€100mg562.00€500mg1,121.00€1mL*10mM (DMSO)108.00€EHT 1864 2HCl
CAS:EHT 1864 (EHT 1864 2HCl) is a Rac family GTPase inhibitor that blocks activation by direct binding to Rac1, Rac1b, Rac2, and Rac3. Cost effective and quality assured.Formula:C25H29Cl2F3N2O4SPurity:98.39% - 99.42%Color and Shape:SolidMolecular weight:581.47Ref: TM-T6483
1mg47.00€5mg92.00€10mg136.00€25mg259.00€50mg472.00€100mg677.00€200mg934.00€1mL*10mM (DMSO)107.00€(E/Z)-ZINC09659342
CAS:(E/Z)-ZINC09659342 is an inhibitor of Lbc-Rho A interaction.Formula:C23H15F3N2O4Purity:95.83%Color and Shape:SolidMolecular weight:440.37Ref: TM-T9986
1mg66.00€5mg145.00€10mg221.00€25mg378.00€50mg533.00€100mg718.00€200mg938.00€1mL*10mM (DMSO)160.00€(Rac)-Antineoplaston A10
CAS:Antineoplaston A10 is the first identified human antineoplaston, naturally occurring with anti-proliferative properties.Formula:C13H14N2O3Purity:98.41%Color and Shape:SolidMolecular weight:246.26Ref: TM-T5379
1mg40.00€5mg88.00€10mg129.00€25mg210.00€50mg311.00€100mg449.00€200mg627.00€1mL*10mM (DMSO)95.00€AZD0022
CAS:AZD0022 is a selective and orally active KRAS G12D inhibitor that displays exposure-dependent pRSK inhibition in a GP2D xenograft model.Formula:C34H30F4N6OColor and Shape:SoildMolecular weight:614.64ML-097
CAS:ML-097 (CID-2160985) is a pan activator of Ras-related GTPasesFormula:C14H11BrO3Purity:99.12%Color and Shape:SolidMolecular weight:307.139Ref: TM-T21970
5mg65.00€10mg95.00€25mg140.00€50mg202.00€100mg303.00€500mg725.00€1mL*10mM (DMSO)71.00€MRTF-A-IN-2
MRTF-A-IN-2 (compound 16) is an inhibitor of MRTF-A. It effectively suppresses cell proliferation and induces senescence in HCC cells.Color and Shape:Odour SolidKRAS G12C inhibitor 59
CAS:KRAS G12C Inhibitor 59 is a compound with anticancer properties.Formula:C32H39F6N7O5Purity:98%Color and Shape:SolidMolecular weight:715.69K-Ras-IN-1
CAS:K-Ras-IN-1 is a K-Ras inhibitor.Formula:C11H13NOSPurity:98.72%Color and Shape:SolidMolecular weight:207.29Ref: TM-T5469
2mg46.00€5mg70.00€10mg101.00€25mg182.00€50mg284.00€100mg424.00€200mg588.00€1mL*10mM (DMSO)77.00€Rhosin hydrochloride
CAS:Rhosin hydrochloride is a specific inhibitor of the RhoA subfamily Rho GTPases.Cost-effective and quality-assured.Formula:C20H20Cl2N6OPurity:97.33% - 98.92%Color and Shape:SolidMolecular weight:431.318Ref: TM-T16745
1mg159.00€2mg217.00€5mg329.00€10mg472.00€25mg753.00€50mg1,026.00€100mg1,378.00€1mL*10mM (DMSO)363.00€EHop-016
CAS:EHop-016 is a specific Rac GTPase inhibitor with IC50 of 1.1 μM for Rac1 in MDA-MB-231 and MDA-MB-435 cells, equally effective inhibition for Rac3.Formula:C25H30N6OPurity:100% - 99.86%Color and Shape:SolidMolecular weight:430.55Ref: TM-T2427
5mg48.00€10mg73.00€25mg127.00€50mg213.00€100mg334.00€200mg492.00€500mg787.00€1mL*10mM (DMSO)52.00€KRAS inhibitor-33
KRAS inhibitor-33 (compound 115a) is a pyrido[2,3-d]pyrimidine derivative that serves as an effective inhibitor of KRAS, exhibiting an IC50 value of ≤ 100nM.Formula:C33H39ClF2N6O3Color and Shape:SolidMolecular weight:641.15
