p38 MAPK
p38 MAPKs are a subgroup of MAPKs that respond to stress signals and are involved in the regulation of inflammation, cell differentiation, apoptosis, and autophagy. p38 MAPK signaling is crucial in immune responses and is implicated in various diseases, including chronic inflammatory conditions, cancer, and neurodegenerative disorders. At CymitQuimica, we provide a comprehensive range of p38 MAPK inhibitors and modulators to support your research in inflammation, stress response, and therapeutic development.
Products of "p38 MAPK"
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SD 0006
CAS:SD 0006 (SD-06) is a MAPK p38 alpha inhibitor( IC50 : 110 nM) for the treatment of arthritis.Formula:C20H20ClN5O2Purity:98.32%Color and Shape:SolidMolecular weight:397.86Ref: TM-T7276
2mg38.00€5mg58.00€10mg90.00€25mg145.00€50mg226.00€100mg338.00€200mg472.00€1mL*10mM (DMSO)65.00€Gypenoside L
CAS:Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release.Formula:C42H72O14Purity:99.42% - 99.65%Color and Shape:SolidMolecular weight:801.01Sertaconazole
CAS:Sertaconazole is a broad-spectrum antifungal.Formula:C20H15Cl3N2OSPurity:95.00%Color and Shape:SolidMolecular weight:437.77Ref: TM-T50005
5mg58.00€10mg82.00€25mg126.00€50mg182.00€100mg273.00€200mg409.00€1mL*10mM (DMSO)84.00€R1487
CAS:R1487 is an orally bioavailable and highly selective p38α mitogen-activated protein kinase inhibitor.Formula:C19H18F2N4O3Purity:99.77%Color and Shape:SolidMolecular weight:388.37AMG-548 dihydrochloride (864249-60-5 free base)
AMG-548 dihydrochloride: oral p38α inhibitor, Ki: 0.5 nM; less so for p38β, Ki: 36 nM; >> p38γ/δ; blocks LPS-induced TNFα, IC50: 3 nM.Formula:C29H29Cl2N5OPurity:98%Color and Shape:SolidMolecular weight:534.48SB 202190
CAS:SB 202190 (FHPI) is a p38 MAPK inhibitor that inhibits p38α and p38β2 (IC50=50/100 nM) selectively and cell-permeably.Formula:C20H14FN3OPurity:98% - 99.84%Color and Shape:Pale YellowMolecular weight:331.34Cornuside
CAS:Cornuside boosts immunity, reduces inflammation, protects heart and liver, and guards against brain injury by modulating stress responses.Formula:C24H30O14Purity:100% - 99.57%Color and Shape:SolidMolecular weight:542.49Ref: TM-T4S2326
1mg96.00€5mg264.00€10mg415.00€25mg677.00€50mg935.00€100mg1,254.00€500mg2,527.00€1mL*10mM (DMSO)315.00€Licarin A
CAS:Licarin A is a natural anti-inflammatory lignan that inhibits PKCα/βII and p38 MAPK pathways, thereby decreasing TNF-α and prostaglandin D2 (PGD2)and COX-2.Formula:C20H22O4Purity:99.5%Color and Shape:SolidMolecular weight:326.39p38 MAP Kinase-IN-1
CAS:p38 MAP Kinase-IN-1 (Compound 4) is an inhibitor of p38, suitable for studies related to inflammation and autoimmune responses.Formula:C20H19FN6OColor and Shape:SolidMolecular weight:378.403BMS582949
CAS:BMS-582949 inhibits p38 MAPK with 13 nM IC50, blocking kinase activity and activation.Formula:C22H26N6O2Purity:98.11%Color and Shape:SolidMolecular weight:406.48Ref: TM-T6789
1mg87.00€2mg120.00€5mg210.00€10mg299.00€25mg502.00€50mg730.00€100mg1,026.00€1mL*10mM (DMSO)210.00€VX 745
CAS:Controlled ProductApplications VX 745 is a potent and selective inhibitor of p38α mitogen-activated protein (MAP) kinase. VX 745 is a potential anti-inflammatory agents. Studies suggest that VX 745 may be useful in the treatment of Werner syndrome. References Haddad, J.J.: Curr. Opin. Invest. Drugs, 2, 1070 (2001); Duffy, J.P. et al.: ACS Med. Chem. Lett., 2, 758 (2011); Bagley, M.C. et al.: Pharmaceuticals, 3, 1842 (2010);Formula:C19H9Cl2F2N3OSColor and Shape:NeatMolecular weight:436.26Pexmetinib
CAS:Pexmetinib (ARRY-614) is an orally bioavailable dual p38 MAPK/Tie-2 inhibitor.Cost-effective and quality-assured.Formula:C31H33FN6O3Purity:98.41% - 99.66%Color and Shape:SolidMolecular weight:556.63Ref: TM-T6934
1mg47.00€5mg97.00€10mg139.00€25mg271.00€50mg435.00€100mg567.00€200mg810.00€1mL*10mM (DMSO)118.00€Aspirin
CAS:Aspirin (Acetylsalicylic Acid) is a COX inhibitor. Aspirin has anti-inflammatory, antipyretic and analgesic activities. Cost-effective and quality-assured.Formula:C9H8O4Purity:99.78% - 99.91%Color and Shape:White Solid CrystallineMolecular weight:180.16Talmapimod
CAS:Talmapimod (SCIO-469): Oral ATP-competitive p38α inhibitor, IC50 = 9 nM (p38α), 90 nM (p38β), >2000-fold selectivity over 20 kinases.Formula:C27H30ClFN4O3Purity:100% - 98%Color and Shape:SolidMolecular weight:513Ref: TM-T12871
1mg52.00€2mg77.00€5mg115.00€10mg177.00€25mg378.00€50mg560.00€100mg800.00€1mL*10mM (DMSO)131.00€p38 Kinase inhibitor 4
CAS:Compound 135, also known as p38 Kinase Inhibitor 4, is a potent inhibitor of p38 [1].Formula:C12H9Cl2N3OPurity:98%Color and Shape:SolidMolecular weight:282.13Andrograpanin
CAS:Andrograpanin (19-HYDROXY-8(17),13-LABDADIEN-16,15-OLIDE) is a bioactive compound from Andrographis paniculata.Formula:C20H30O3Purity:99.03%Color and Shape:SolidMolecular weight:318.45Acumapimod
CAS:Acumapimod (BCT-197) is an orally active inhibitor of p38α MAPK (IC50 <1 μM).Formula:C22H19N5O2Purity:≥95%Color and Shape:SolidMolecular weight:385.42SB 239063
CAS:SB 239063 (SB239063) is a potent and selective p38 MAPKα/β inhibitor with IC50 of 44 nM, showing no activity against the γ- and δ-kinase isoforms.Formula:C20H21FN4O2Purity:99.42% - 99.81%Color and Shape:SolidMolecular weight:368.4
