Sodium Channel
Sodium channels are essential membrane proteins that allow the passage of sodium ions (Na+) across the cell membrane, generating and propagating electrical signals in neurons, muscle cells, and other excitable tissues. These channels are vital for the initiation and conduction of action potentials, making them crucial in processes such as nerve impulse transmission, muscle contraction, and cardiac function. Dysregulation of sodium channels can lead to neurological disorders, arrhythmias, and chronic pain conditions. At CymitQuimica, we provide a variety of sodium channel modulators to support your research in neurobiology, cardiology, and pain management.
Products of "Sodium Channel"
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2-Diisopropylaminoethyl Chloride Hydrochloride-d14
CAS:Controlled ProductApplications 2-Diisopropylaminoethyl Chloride Hydrochloride-d14 is an intermediate in synthesizing Disopyramide-d14 Tosylate Salt (D493452). Antiarrhythmic (class IA). Sodium channel blocker. References Adelstein, et al.: J. Med. Chem., 16, 309 (1973); Czeisler, J.L., et al.: J. Pharm. Sci., 74, 750 (1985); Taylor, E.H., et al.: Ann. Clin. Lab. Sci., 16, 289 (1986);Formula:C8H4D14ClN·HClColor and Shape:NeatMolecular weight:177.77 + 36.46Dronedarone
CAS:Dronedarone (SR 33589) is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.Formula:C31H44N2O5SPurity:98.85% - 99.58%Color and Shape:SolidMolecular weight:556.763-Deoxyaconitine
CAS:Controlled ProductApplications 3-Deoxyaconitine is a derivative of Aconitine (A189875), which activates tetrodotoxin-sensitive Na+ channels, inducing presynaptic depolarization, thus blocking the nerve action potential which, in turn, blocks the release of neurotransmitters and decreases the end plate potential at the neuromuscular junction. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Derbre, S., et al.: Anal. Bioanal. Chem., 398, 1747 (2010), Li, M., et al.: J. Pharm. Biomed. Anal., 53, 1063 (2010),Formula:C34H47NO10Color and Shape:NeatMolecular weight:276.322Bupivacaine
CAS:Bupivacaine (AH-250) is a NMDA receptor inhibitor.Bupivacaine can block sodium, L-calcium, and potassium channels.Bupivacaine potently blocks SCN5A channelsFormula:C18H28N2OPurity:100%Color and Shape:SolidMolecular weight:288.43Halofuginone hydrobromide
CAS:Halofuginone specifically inhibits collagen type I and MMP-2 gene expression, which may result in the suppression of angiogenesis and tumor cell growth.Formula:C16H17BrClN3O3·HBrPurity:97.01% - 98.5%Color and Shape:SolidMolecular weight:495.59Ref: TM-T3524
1mg37.00€2mg52.00€5mg79.00€10mg112.00€25mg219.00€50mg328.00€100mg495.00€500mg947.00€1mL*10mM (DMSO)88.00€4-[[1-[[2-Chloro-5-(trifluoromethyl)phenyl]methyl]-4-piperidinyl]methoxy]-5-cyclopropyl-2-fluoro-N-(methylsulfonyl)-benzamide
CAS:Controlled ProductFormula:C25H27ClF4N2O4SColor and Shape:NeatMolecular weight:563.005Phenytoin
CAS:Phenytoin: a non-sedative hydantoin, antiepileptic with anticonvulsant effects, stabilizes neurons, prevents seizure spread, and relaxes muscles.Formula:C15H12N2O2Purity:99.95%Color and Shape:Needles (Alcohol) Tasteless (Ntp 1992)Molecular weight:252.27Aneratrigine hydrochloride
CAS:Aneratrigine hydrochloride is a Nav 1.9 blocker that may be used to prevent or treat sodium channel blocker-related disorders.Formula:C19H21Cl2F2N5O2S2Purity:99.33% - 99.39%Color and Shape:SolidMolecular weight:524.43Ralfinamide
CAS:Ralfinamide (Priralfinamide) is an orally available Na-channel blocker for the treatment of neuropathic pain and other pain conditions.Formula:C17H19FN2O2Purity:99.41%Color and Shape:SolidMolecular weight:302.34Dimethyl lithospermate B
CAS:Dimethyl lithospermate B (dmLSB) is a selective Na+ channel agonist.Formula:C38H34O16Purity:98.34% - 99.62%Color and Shape:SolidMolecular weight:746.67Ref: TM-T8299
1mg170.00€5mg455.00€10mg652.00€25mg998.00€50mg1,320.00€100mg1,795.00€1mL*10mM (DMSO)550.00€GDC-0276
CAS:GDC-0276 is an orally active, selective, and potent NaV1.7 inhibitor that can be used for the study of pain-related diseases.Formula:C24H31FN2O4SPurity:99.77%Color and Shape:SolidMolecular weight:462.582-Butoxyquinoline-4-carboxylic Acid
CAS:Applications 2-Butoxyquinoline-4-carboxylic Acid is used in the organic synthesis of o-(β-diethylaminoethyl)cinchoninaldoxime with local anesthetic activity References Rossi, S., et al.: Farmaco, Edizione Scientifica, 34, 486 (1979)Formula:C14H15NO3Color and Shape:NeatMolecular weight:245.27Propoxycaine hydrochloride
CAS:Propoxycaine hydrochloride is an ester local anesthetic that inhibits voltage-gated sodium channels, modulates nerve impulses, and induces loss of sensation.Formula:C16H27ClN2O3Purity:97.25%Color and Shape:SolidMolecular weight:330.85Ropivacaine N-Oxide
CAS:Controlled ProductApplications The N-oxide of the local anesthetic Ropivacaine (R675000).Formula:C17H26N2O2Color and Shape:Off-WhiteMolecular weight:290.4Tributyl O-Acetylcitrate-d3
CAS:Controlled ProductApplications Labelled Tributyl O-Acetylcitrate (T772950). Topical pharmaceutical formulation anesthetic surfactant ester. References Cherian., et al.: Br. J. Anaesthesia, 87, 502 (2001),Formula:C20D3H31O8Color and Shape:NeatMolecular weight:405.50Disopyramide-d14 Tosylate Salt
CAS:Controlled ProductApplications Antiarrhythmic (class IA). Sodium channel blocker. References Adelstein, et al.: J. Med. Chem., 16, 309 (1973), Czeisler, J.L., et al.: J. Pharm. Sci., 74, 750 (1985), Taylor, E.H., et al.: Ann. Clin. Lab. Sci., 16, 289 (1986),Formula:C21H15D14N3O•C7H8O3SColor and Shape:NeatMolecular weight:525.76Mepivacaine
CAS:Mepivacaine (Carbocaine) is an amide local anesthetic, blocking sodium channels for nerve blocks and epidurals.Formula:C15H22N2OPurity:99.35%Color and Shape:SolidMolecular weight:246.35BMS 204352
CAS:Controlled ProductApplications BMS 204352 is a potassium channel opener that can be used to treat stroke. References Jensen, S. B.: CNS Drug. Rev. 8, 353 (2002); Gribkoff, V. K., et al.: Nat Med 7, 471 (2001)Formula:C16H10ClF4NO2Color and Shape:NeatMolecular weight:359.703Funapide
CAS:Funapide (TV 45070) is a potent Nav1.7 inhibitor, potentially treating inflammation and various pains.Formula:C22H14F3NO5Purity:100%Color and Shape:SolidMolecular weight:429.35Ref: TM-T15358
1mg127.00€5mg305.00€10mg464.00€25mg747.00€50mg1,008.00€100mg1,359.00€1mL*10mM (DMSO)335.00€Licarbazepine
CAS:Licarbazepine (10,11-hydroxy-10,11 Dihydrocarbamezer) is the pharmacologically active metabolite of oxcarbazepine, a drug indicated for the treatment of partialFormula:C15H14N2O2Purity:99.11%Color and Shape:SolidMolecular weight:254.28
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