Sodium Channel
Sodium channels are essential membrane proteins that allow the passage of sodium ions (Na+) across the cell membrane, generating and propagating electrical signals in neurons, muscle cells, and other excitable tissues. These channels are vital for the initiation and conduction of action potentials, making them crucial in processes such as nerve impulse transmission, muscle contraction, and cardiac function. Dysregulation of sodium channels can lead to neurological disorders, arrhythmias, and chronic pain conditions. At CymitQuimica, we provide a variety of sodium channel modulators to support your research in neurobiology, cardiology, and pain management.
Products of "Sodium Channel"
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Amiloride Hydrochloride
CAS:Applications Sodium channel blocker. Diuretic. References Paterson, J., et al.: Br. Med. J., 1, 422 (1968), Khan, K., et al.: J. Pharm. Pharmacol., 27, 48 (1975), Frank, S., et al.: J. Pharm. Sci., 64, 1585 (1975), Vidt, D., et al.: Pharmacotherapy, 1, 179 (1981),Formula:C6H8ClN7O·ClHColor and Shape:Light YellowMolecular weight:266.09Indazole
CAS:Indazole, a heterocyclic compound, offers diverse biological activities.Formula:C7H6N2Purity:100% - 99.85%Color and Shape:White Or Beige Crystalline PowderMolecular weight:118.14Metergoline
CAS:Metergoline (Methergoline) is a dopamine agonist and serotonin antagonist.Formula:C25H29N3O2Purity:99.7% - 99.83%Color and Shape:SolidMolecular weight:403.52Diphenidol hydrochloride
CAS:Diphenidol hydrochloride (Difenidol hydrochloride), a muscarinic antagonist, is employed as an anti-vertigo and as an antiemetic drug.Formula:C21H28ClNOPurity:99.15% - 99.33%Color and Shape:Crystals Soluble In Methanol WaterMolecular weight:345.91Ropivacaine-d7 Hydrochloride
CAS:Controlled ProductStability Hygroscopic Applications Labelled Ropivacaine (R675000). Anesthetic (local). References Cederholm. I., et al.: Reg. Anesth., 19, 18 (1994), Johansson, B., et al.: Anesth. Analg., 78, 210 (1994), Oda, Y., et al.: Anesthesiology, 82, 214 (1995),Formula:C17H20D7ClN2OColor and Shape:White To Off-WhiteMolecular weight:317.91NaV1.2/1.6 channel blocker-1
CAS:NaV1.2/1.6 channel blocker-1 is a NaV1.2/1.6 channel blocker that inhibits rNaV1.6 and can be used to study generalised epilepsy and movement disorders.Formula:C14H14N2OSPurity:99.54%Color and Shape:SolidMolecular weight:258.34Oxcarbazepine
CAS:Oxcarbazepine (GP 47680), an anti-epileptic, reduces CNS disorganized electrical activity.Formula:C15H12N2O2Purity:98.46%Color and Shape:Crystals From Ethanol SolidMolecular weight:252.27Ref: TM-T0440
5mg37.00€10mg52.00€25mg81.00€50mg92.00€100mg139.00€200mg175.00€500mg235.00€1mL*10mM (DMSO)58.00€ProTx II TFA
ProTx-II TFA is a potent and highly selective Nav1.7 sodium channel blocker, exhibiting an IC50 of 0.3 nM and demonstrating at least 100-fold selectivity overFormula:C168H250N46O41S8·xC2HF3O2Purity:98%Color and Shape:SolidMolecular weight:3826.59 (free base)BI-9627
CAS:BI-9627 is an inhibitor of sodium-hydrogen exchanger isoform 1 (NHE1) (EC50: 31 nM).Formula:C16H19F3N4O2Color and Shape:SolidMolecular weight:356.34VGSCs-IN-1
CAS:VGSCs-IN-1, a VGSC inhibitor and Riluzole analog, exhibits good blocking activity on Nav1.4 and can be used to study cellular excitability disorders.Formula:C12H12F3N3OSPurity:99.50%Color and Shape:SolidMolecular weight:303.32-(Diethylamino)-N-(2,5-dimethylphenyl)acetamide Hydrochloride
CAS:Controlled ProductImpurity Lidocaine EP impurity J Applications 2-(Diethylamino)-N-(2,5-dimethylphenyl)acetamide Hydrochloride is an impurity in the synthesis of Lidocaine Hydrochloride (L397800), an anesthetic local agent and antiarrythmic class IB agent. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Duce, R., et al.: J. Pharmacol. Exp. Ther., 179, 580 (1971), Kronberg, G.H., et al.: J. Med. Chem., 16, 739 (1973), Groningsson, K., et al.: Anal. Profiles Drug Subs., 14, 207 (1985), Davies, P.S., et al.: Drugs, 64, 937 (2004),Formula:C14H22N2O·ClHColor and Shape:NeatMolecular weight:270.80Halazone
CAS:Halazone (Pantocid) is fine white powder with an odor of chlorine. It has been widely used to disinfect drinking water.Formula:C7H5Cl2NO4SPurity:90%Color and Shape:Physical Description Fine White Powder With An Odor Of Chlorine (Ntp 1992)Molecular weight:270.09Orthocaine
CAS:Controlled ProductApplications Anesthetic (topical). References Olson, L., et al.: J. Imaging Sci. Technol., 51, 217 (2007),Formula:C8H9NO3Color and Shape:NeatMolecular weight:167.164-Methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylic Acid-d7
CAS:Controlled ProductApplications 4-Methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylic Acid-d7 is the labelled form of 4-Methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylic Acid (M326815). 4-Methyl-3-[[1-oxo-2-(propylamino)propyl]amino]-2-thiophenecarboxylic Acid is an impurity of Articaine (A777900), an amide based short-acting local anesthetic use for regional anaesthesia in day-case settings such arthroscopy, hand, food surgery and in dentistry. References Grossman, M., et al.: J. Clin. Pharmacol., 44, 1282 (2004); Oertel, R., et al.: Pharmazie., 53, 646 (1998); Vree, T.B., et al.: Brit. J. Clin. Pharmacol., 44, 29 (1997)Formula:C12H11D7N2O3SColor and Shape:NeatMolecular weight:277.39(Rac)-AMG8379
CAS:(Rac)-AMG8379 ((Rac)-AMG8380) is a racemate of AMG8379 which is an orally active and selective sulfonamide NaV1.7 antagonist.Formula:C25H16ClF2N3O5SPurity:99.6%Color and Shape:SolidMolecular weight:543.93Ref: TM-T12655
1mg185.00€2mg279.00€5mg425.00€10mg625.00€25mg938.00€50mg1,311.00€100mg1,795.00€500mg3,591.00€1mL*10mM (DMSO)540.00€2,6-Dimethylaniline Hydrochloride
CAS:Controlled ProductImpurity Ropivacaine EP Impurity H Applications 2,6-Dimethylaniline Hydrochloride (Ropivacaine EP Impurity H) is chemical reagent frequently used in the synthesis of pharmaceutical compounds. Impurity of Ropivacaine (R675000), anesthetic (local). References Li, H. et al.: J. Polym. Sci. A. Poly. Chem., 44, 2665 (2006); Cederholm. I., et al.: Reg. Anesth., 19, 18 (1994), Johansson, B., et al.: Anesth. Analg., 78, 210 (1994), Oda, Y., et al.: Anesthesiology, 82, 214 (1995); Lv, C. et al.: Chem. A Eur. J., 19, 1174 (2013);Formula:C8H11N·ClHColor and Shape:White To Light BrownMolecular weight:157.64Mexiletine Hydrochloride
CAS:Controlled ProductApplications Antiarrhythmic (class IB). References Singh, E.M., et al.: Br. J. Pharmacol., 44, 1 (1972); Scott, K.N., et al.: Drug Metab. Dispos., 1, 506 (1973); Chew, C.Y.C., et al.: Drugs, 17, 161 (1979); Abounassif, M.A., et al.: Anal. Profiles Drug Subs., 20, 433 (1991);Formula:C11H17NO·ClHColor and Shape:WhiteMolecular weight:215.72BI 01383298
CAS:BI 01383298 is a selective inhibitor of the sodium-citrate co-transporter (SLC13A5).Formula:C19H19Cl2FN2O3SPurity:99.71%Color and Shape:SolidMolecular weight:445.34Mepivacaine N-Oxide
CAS:Controlled ProductApplications The N-oxide derivative of the local anesthetic Mepivacaine (M225060).Formula:C15H22N2O2Color and Shape:White To BeigeMolecular weight:262.35Elpetrigine
CAS:Elpetrigine (GW273293) is a potential sodium channel blocker with antiepileptic activity that can be used to study epilepsy.Formula:C10H7Cl3N4Purity:98.77% - 99.78%Color and Shape:SolidMolecular weight:289.55
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