Calcium Channel
Calcium channels are membrane proteins that regulate the flow of calcium ions into and out of cells, which is essential for various cellular functions, including muscle contraction, neurotransmitter release, and gene expression. Dysregulation of calcium channel activity is associated with conditions such as hypertension, cardiac arrhythmias, and neurological disorders. At CymitQuimica, we provide a wide selection of calcium channel modulators to support your research in cardiovascular health, neurobiology, and signal transduction.
Products of "Calcium Channel"
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(3-(tert-Butyl)-1H-pyrazol-5-yl)methanol
CAS:Controlled ProductApplications (3-(tert-butyl)-1H-pyrazol-5-yl)methanol (cas# 493038-53-2) is a useful research chemical.Formula:C8H14N2OColor and Shape:White To Off-WhiteMolecular weight:154.21Almorexant
CAS:Almorexant (ACT 078573), a strong dual orexin receptor antagonist, has Ki of 1.3 nM for OX1 and 0.17 nM for OX2.Formula:C29H31F3N2O3Purity:97.75% - 98.02%Color and Shape:SolidMolecular weight:512.56d-Glaucine-d6
CAS:Controlled ProductApplications d-Glaucine-d6 is labelled d-Glaucine (G406900) which has bronchodilator and antiinflammatory effects, acting as a PDE4 inhibitor and calcium channel blocker, and is used medically as an antitussive in some countries. References Cortijo, J., et al.: Brit. J. Pharm., 127, 1641 (1999); Rühle, K., et al.: Brit. J. Clin. Pharm., 17, 521 (1984)Formula:C21H19D6NO4Color and Shape:NeatMolecular weight:361.46Ginsenoside Ro
CAS:Ginsenoside Ro (Chikusetsusaponin V) can reduce TXA2 production, weakly reduce COX-1 and TXAS activities, and has antiplatelet effects as a Ca2+ antagonist withFormula:C48H76O19Purity:98% - 99.8%Color and Shape:SolidMolecular weight:957.11BBT
CAS:BBT has anti-hyperglycemic activity, protecting beta cells from cytokine or streptozotocin-induced cell death, and restoring beta cell function.Formula:C18H12BrNO2SPurity:99.02%Color and Shape:SolidMolecular weight:386.26Ambocin
CAS:Ambocin is a natural product from Pueraria mirifica.Formula:C26H28O14Purity:98%Color and Shape:SolidMolecular weight:564.49N-Desmethyl-N-acetyl Diltiazem
Controlled ProductApplications N-Desmethyl-N-acetyl Diltiazem is a metabolite of Diltiazem (D460620, HCl); a calcium channel blocker with vasodilating activity. Also anti-anginal, anti-hypertensive, and anti-arrhythmic (class IV). References Sato, et al.: Arzneim.-Forsch., 21, 1338 (1971); Smirnov, S.R.: Eur. J. Pharmacol., 360, 81 (1998); Hansson, L., et al.: Lancet, 356, 359 (2000)Formula:C23H26N2O5SColor and Shape:NeatMolecular weight:442.53ORM-10962
CAS:ORM-10962 is a potent, highly selective inhibitor of sodium-calcium exchanger (NCX) (for the reverse and forward mode inhibition with IC50 values of 67 and 55Formula:C27H29N3O4Purity:98%Color and Shape:SolidMolecular weight:459.54Levamlodipine besylate Hemipentahydrate
CAS:Levamlodipine besylate hemipentahydrate is the besylate hemipentahydrate salt form of Levamlodipine. It is an orally effective calcium channel blocker with antioxidative and vasodilatory properties. This compound can reduce serum malondialdehyde (MDA) levels, enhance the activity of superoxide dismutase (SOD), and alleviate oxidative stress. Levamlodipine besylate hemipentahydrate is relevant for research in vascular dementia, hypertension, and cerebrovascular diseases.Formula:C20H25ClN2O5·C6H6O3SH2OColor and Shape:SolidMolecular weight:1224.18Myomodulin
CAS:Myomodulin is a neuropeptide present in molluscs, insects, and gastropods.Myomodulin is present in two identified aplysia neurons that contain myomodulin A theFormula:C36H67N11O8S2Purity:98%Color and Shape:SolidMolecular weight:846.122-(3-Chlorophenyl)-2-methylpropan-1-amine
CAS:Controlled ProductApplications 2-(3-Chlorophenyl)-2-methylpropan-1-amine was used for the preparation of pyrimidinediones as antagonists of L-type calcium channels (LTCC) for potential use in the treatment of Parkinson’s disease. References Kang, S., et al.: J. Med. Chem., 56, 4786-4797 (2013)Formula:C10H14ClNColor and Shape:NeatMolecular weight:183.68GV-58
CAS:GV-58 agonizes N/P-Q-type Ca2+ channels (EC50: 7.21/8.81 μM) with 20x less inhibition on CDK kinases.Formula:C18H26N6OSPurity:97.36%Color and Shape:SolidMolecular weight:374.5Ref: TM-T11517
1mg51.00€5mg144.00€10mg216.00€25mg432.00€50mg625.00€100mg873.00€500mg1,738.00€1mL*10mM (DMSO)159.00€trans-Ned 19
CAS:trans-Ned 19 blocks NAADP and TPC, hindering calcium signaling and aorta relaxation at low histamine levels.Formula:C30H31FN4O3Purity:98%Color and Shape:SolidMolecular weight:514.59Azelnidipine
CAS:Azelnidipine (UR-12592) is a dihydropyridine used as calcium channel blocker.Formula:C33H34N4O6Purity:99.28%Color and Shape:Light Yellowish PowderMolecular weight:582.65Ref: TM-T0121
5mg50.00€10mg67.00€25mg109.00€50mg172.00€100mg309.00€200mg500.00€500mg800.00€1mL*10mM (DMSO)74.00€1,2,4-Trihydroxybenzene
CAS:1,2,4-Trihydroxybenzene (Benzene-1,2,4-triol) is a by-product of coffee bean roasting and is found in mouse, arabica coffee.1,2,4-Trihydroxybenzene is aFormula:C6H6O3Purity:97.16%Color and Shape:SolidMolecular weight:126.11Lercanidipine-d3 Hydrochloride
CAS:Controlled ProductFormula:C36D3H38N3O6·HClColor and Shape:NeatMolecular weight:651.21Nicardipine O-Desmethyl-O-methyl(phenylmethyl)amino]ethyl) Ester Hydrochloride
CAS:Applications Nicardipine (N394500) impurity. Nicardipine is a dihydropyridine calcium channel blocker. Antianginal; antihypertensive. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Satoh, K., et al.: Clin. Exp. Pharmacol. Physiol., 7, 249 (1980), Sorkin, E.M., et al.: Drugs, 33, 296 (1987),Formula:C35H40N4O6·x(HCl)Color and Shape:NeatMolecular weight:612.723646Gallopamil hydrochloride
CAS:Gallopamil hydrochloride (Methoxyverapamil hydrochloride) is an antagonist of phenylalkylamine calcium.Formula:C28H41ClN2O5Purity:99.02%Color and Shape:SolidMolecular weight:521.09Ref: TM-T11353L
1mg38.00€5mg73.00€10mg90.00€25mg140.00€50mg183.00€100mg283.00€500mg692.00€1mL*10mM (DMSO)90.00€Diproteverine HCl
CAS:Diproteverine HCl is a novel calcium antagonist with antianginal properties, antispasmodic and vasoactive.Formula:C26H36ClNO4Purity:99.38% - 99.44%Color and Shape:SolidMolecular weight:462.02JTV-519 fumarate
CAS:Ryanodine receptor (RyR) inhibitor; stabilizes RyR2 in a closed conformation. Exhibits antiarrhythmic and cardioprotective properties in vivo.Formula:C29H36N2O6SColor and Shape:SolidMolecular weight:540.67
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