Calcium Channel
Calcium channels are membrane proteins that regulate the flow of calcium ions into and out of cells, which is essential for various cellular functions, including muscle contraction, neurotransmitter release, and gene expression. Dysregulation of calcium channel activity is associated with conditions such as hypertension, cardiac arrhythmias, and neurological disorders. At CymitQuimica, we provide a wide selection of calcium channel modulators to support your research in cardiovascular health, neurobiology, and signal transduction.
Products of "Calcium Channel"
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Cinnarizine
CAS:Cinnarizine is a piperazine, blocks H1-receptor & Ca-channels, has vasodilating & antiemetic effects, may cause Parkinson-like symptoms.Formula:C26H28N2Purity:99.94%Color and Shape:SolidMolecular weight:368.51cis Lacidipine
CAS:Controlled ProductStability Light Sensitive Applications Z-Isomer of Lacidipine; a dihydropyridine calcium channel blocker. Antihypertensive. References Safar, M., et al.: Clin. Pharmacol. Ther., 46, 94 (1989), Kharat, V.R., et al.: J. Pharm. Biomed. Anal., 28, 789 (2002), McCormack, A.J., et al.: Drugs, 63, 2327 (2003),Formula:C26H33NO6Color and Shape:NeatMolecular weight:455.54Lifarizine
CAS:Lifarizine (RS-87476), a calcium-sodium channel antagonist, shows neuroprotective activity in a simplified rat survival model of double vessel occlusion.Formula:C29H32N4Purity:99.12%Color and Shape:SolidMolecular weight:436.59Ranolazine
CAS:Ranolazine (RS 43285-003) inhibits calcium uptake, treats chronic angina by targeting sodium/calcium channels to modulate intracellular sodium.Formula:C24H33N3O4Purity:98.13%Color and Shape:White SolidMolecular weight:427.541-[(2-Chlorophenyl)phenylmethyl]piperazine
CAS:Controlled ProductApplications 1-[(2-Chlorophenyl)phenylmethyl]piperazine is a novel compound derived from the previously reported N-type calcium channel blocker NP118809 (1-(4-benzhydrylpiperazin-1-yl)-3,3-diphenylpropan-1-one). References Maggi, C., et al.: Neuroscience, 34, 243 (1990), Evans, A., et al.: Brain Res., 712, 265 (1996), Kerr, L., et al.: Eur. J. Pharmacol., 146, 181 (1998), Hu, L., et al.: Bioorg. Med. Chem. Lett., 9, 907 (1999),Formula:C16H28N2O11Color and Shape:NeatMolecular weight:424.4ML218
CAS:ML218 is an inhibitor of T-type Ca2+ channels (Cav3.1, Cav3.2, Cav3.3).ML218 inhibits the synaptic activity of subthalamic nucleus (STN) neurons.Formula:C19H26Cl2N2OPurity:99.2% - 99.45%Color and Shape:SolidMolecular weight:369.33Lercanidipine hydrochloride
CAS:Lercanidipine hydrochloride (Corifeo) is a calcium channel blocker of the dihydropyridine class.Formula:C36H41N3O6·HClPurity:100% - 99.86%Color and Shape:Pale-Yellow PowderMolecular weight:648.19Verapamil
CAS:Verapamil (CP-16533-1), an oral calcium channel blocker, inhibits P-gp and CYP3A4, used for hypertension, arrhythmias, and angina research.Formula:C27H38N2O4Purity:99.53%Color and Shape:OilMolecular weight:454.6Ref: TM-T20656
10mg35.00€25mg51.00€50mg73.00€100mg96.00€200mg143.00€500mg230.00€1mL*10mM (DMSO)55.00€Cromolyn sodium
CAS:Cromolyn sodium (FPL-670) is a chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells.Formula:C23H14Na2O11Purity:98.25% - 99.95%Color and Shape:Colorless Crystals From Ethanol + Ether White Crystalline PowderMolecular weight:512.33MP-010
CAS:MP-010 is an FKBP12 ligand that regulates cytosolic calcium by stabilizing RyR channel activity. It facilitates functional improvement in SOD1G93A mice with amyotrophic lateral sclerosis (ALS), evidenced by enhanced motor coordination, increased integrity of neuromuscular junctions, and significantly higher spinal motor neuron survival rates. MP-010 is applicable for research in the field of neurological disorders.Formula:C14H20N4O2SColor and Shape:SolidMolecular weight:308.399Topiramate
CAS:Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures.Formula:C12H21NO8SPurity:99.79% - 99.92%Color and Shape:White To Off-White Crystalline PowderMolecular weight:339.36Dehydro Amlodipine Besylate
CAS:Controlled ProductApplications Dehydro Amlodipine Besylate is an impurity of Amlodipine (A633495), a dihydropyridine calcium channel blocker; activity resides mainly in the (-)-isomer. References Arrowsmith, J.E., et al.: J. Med. Chem., 29, 1696 (1986); Burges, R.A., et al.: J. Cardiovasc. Pharmacol., 9, 110 (1987); Haria, M., et al.: Drugs, 50, 560 (1995)Formula:C2023ClN2O5·C6H6O3SColor and Shape:NeatMolecular weight:565.04Nepetin
CAS:Nepetin (6-Methoxyluteolin) has antioxidant activity, it is a potent inhibitor of histamine release and calcium influx via down-regulation of the FcεRI α chain.Formula:C16H12O7Purity:99.91% - 99.96%Color and Shape:SolidMolecular weight:316.26Ref: TM-TN1154
1mg70.00€5mg160.00€10mg250.00€25mg424.00€50mg612.00€100mg842.00€1mL*10mM (DMSO)212.00€Gabapentin
CAS:Gabapentin (Neurontin) is an Anti-epileptic Agent.Formula:C9H17NO2Purity:99.55% - 99.91%Color and Shape:White To Off-White Crystalline Solid; Crystals From Ethanol/Ether SolidMolecular weight:171.24TPC2-A1-P
CAS:TPC2-A1-P is a TPC2 agonist that can differentially activate two-pore channel 2 (TPC2) and mimic the activation of TPC2 with NAADP and PIP (2).Formula:C20H21BrF3NO3Purity:98.49%Color and Shape:SolidMolecular weight:460.29Ref: TM-T36806
1mg97.00€5mg236.00€10mg394.00€25mg750.00€50mg1,216.00€100mg1,853.00€1mL*10mM (DMSO)240.00€VU 0240551
CAS:VU 0240551 is a selective antagonist of neuronal K-Cl cotransporter KCC2 inhibitor with an IC50 of 560 nM. VU 0240551 inhibits L-type calcium channels and hERG.Formula:C16H14N4OS2Purity:99.72%Color and Shape:SolidMolecular weight:342.44Ref: TM-TQ0139
1mg37.00€5mg78.00€10mg125.00€25mg255.00€50mg439.00€100mg705.00€200mg938.00€500mg1,415.00€1mL*10mM (DMSO)86.00€Norbormide
CAS:Controlled ProductApplications Norbormide is used as a rodenticide. It acts as a vasoconstrictor and calcium channel blocker, but is selectively toxic to rats and has relatively low toxicity to other species, due to a species specific action of opening the permeability transition pores in rat mitochondria. References Rennison, D., et al.: Bioorg. Med. Chem., 15, 2963 (2007); Zulian, A., et al.: Biochimica et Biophysica Acta, 1767, 980 (2007)Formula:C33H25N3O3Color and Shape:White To Off-WhiteMolecular weight:511.57SEA0400
CAS:SEA0400 is a selective inhibitor of the Na+/Ca2+ exchanger.Formula:C21H19F2NO3Purity:98.11% - 99.29%Color and Shape:SolidMolecular weight:371.38Ref: TM-T3508
1mg39.00€2mg50.00€5mg81.00€10mg131.00€25mg230.00€50mg378.00€100mg567.00€500mg1,254.00€1mL*10mM (DMSO)74.00€NAADP sodium
NAADP sodium is a Ca2+ motor second messenger that targets Ca(2+) channels and can be used to study cancer and immune dysfunction.Formula:C21H27N6O18P3Color and Shape:SolidMolecular weight:744.39JTV-519
CAS:K201 (JTV-519) is a Ca2+-dependent blocker and prevents abnormal Ca(2+) leak from the sarcoplasmic reticulum in the ischemic heart and skeletal muscle (SkM) byFormula:C25H33ClN2O2SPurity:99.8%Color and Shape:SolidMolecular weight:461.06Ref: TM-T24239
1mg60.00€5mg110.00€10mg155.00€25mg248.00€50mg365.00€100mg545.00€500mg1,188.00€1mL*10mM (DMSO)134.00€
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