Casein Kinase
Casein kinases are a family of serine/threonine protein kinases that regulate various cellular processes, including DNA repair, circadian rhythms, and signal transduction. These kinases are involved in the phosphorylation of numerous proteins and are implicated in diseases such as cancer, neurodegenerative disorders, and metabolic syndromes. At CymitQuimica, we offer a selection of casein kinase inhibitors to support your research in signal transduction, cell cycle regulation, and therapeutic development.
Products of "Casein Kinase"
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IWP-2
CAS:IWP-2 is a Wnt pathway inhibitor and an ATP-competitive CK1δ inhibitor. IWP-2 inhibits self-renewal of embryonic stem cells. Cost effective and quality assured.Formula:C22H18N4O2S3Purity:96.1% - 99.49%Color and Shape:SolidMolecular weight:466.6Casein kinase 1δ-IN-13
CAS:Casein kinase1δ-IN-13 (compound 401) is an inhibitor of Casein kinase1δ. It is utilized in the research of neurodegenerative diseases.Formula:C15H13N3O2SColor and Shape:SolidMolecular weight:299.35Casein Kinase II Inhibitor IV
CAS:Casein kinase II inhibitor IV is an effective small molecule inducer, which can be used to induce epidermal keratinocyte differentiation.Formula:C24H23N5O3Purity:98.81% - 99.32%Color and Shape:SolidMolecular weight:429.47Ref: TM-T10687
1mg87.00€5mg170.00€10mg259.00€25mg429.00€50mg605.00€100mg815.00€500mg1,624.00€1mL*10mM (DMSO)180.00€TTP 22
CAS:TTP 22: ATP-competitive CK2 inhibitor; IC50/Ki: 0.1 μM/40 nM; >250x selective over JNK3, ROCK1, MET.Formula:C16H14N2O2S2Purity:97.08% - 97.78%Color and Shape:SolidMolecular weight:330.42CK1δ-IN-9
CAS:CK1δ-IN-9 (Compound 8) is an inhibitor of casein kinase 1 (CK1), specifically targeting CK1δ with an IC50 of 1.4 nM. The compound also inhibits p38α and p38β with IC50 values of 0.25 μM and 0.78 μM, respectively. CK1δ-IN-9 exhibits favorable pharmacokinetic properties, including high oral bioavailability (70%) and moderate clearance.Formula:C16H12FN5Color and Shape:SolidMolecular weight:293.298SGC-CK2-1
CAS:SGC-CK2-1, a CK2 inhibitor, is a inducer of insulin production and secretion in pancreatic β-cells.Formula:C20H21N7OPurity:99.41%Color and Shape:SolidMolecular weight:375.43CK1-IN-2
CAS:CK1-IN-2 (compound Nr.4) is a potent inhibitor of CK1, exhibiting IC50 values of 123 nM for CK1a, 19.8 nM for CK1d, 26.8 nM for CK1e, and 74.3 nM for p38a [1].Formula:C17H12FN3O2Purity:98%Color and Shape:SolidMolecular weight:309.29CZP-IN-1
CZP-IN-1 (compound SH-1) is an inhibitor targeting the pathogen Trypanosoma cruzi protease (CZP) without affecting cathepsin L (IC50=28 nM). This compound is applicable in Chagas disease research.Formula:C20H26N4O4SColor and Shape:SolidMolecular weight:418.51Casein kinase 1δ-IN-4
CAS:"Casein kinase 1δ-IN-4 (compound 567) is a potent inhibitor of casein kinase 1δ with potential application in Alzheimer's disease research [1]."Formula:C16H12N6SPurity:98%Color and Shape:SolidMolecular weight:320.37CSNK2-IN-2
CSNK2-IN-2 (compound 2) is an orally active inhibitor of CSNK2. It is utilized in antiviral research.Formula:C25H30FN9OColor and Shape:SolidMolecular weight:491.56WAY-297174
CAS:WAY-297174 is a human protein kinase CK2 inhibitor with IC50 of > 33 μM.Formula:C11H12N2O2S2Purity:99.43%Color and Shape:SoildMolecular weight:268.36Ref: TM-T60067
1mg84.00€5mg163.00€10mg229.00€25mg379.00€50mg568.00€100mg810.00€500mg1,644.00€1mL*10mM (DMSO)155.00€Casein kinase 1δ-IN-27
CAS:Casein kinase1δ-IN-27 (Compound 8) is an inhibitor of casein kinase 1 (CK1), effectively inhibiting CK1α, CK1δ, CK1ε, and p38α with IC50 values of 22, 16.5, 9.41, and 14.8 nM, respectively. It also suppresses DUX4 expression, with an IC50 of 10 nM.Formula:C21H19FN6Color and Shape:SolidMolecular weight:374.414p38α inhibitor 8
CAS:p38α inhibitor8 (Compound 1) demonstrates inhibitory activity against p38αMAPK and CK1δ, with IC50 values of 0.21 µM and 0.202 µM, respectively.Formula:C17H13FN6Color and Shape:SolidMolecular weight:320.324CK2-IN-13
CK2-IN-13 (compound 12c) is a potent inhibitor of CK2, with an IC50 value of 5.8 nM, playing a significant role in cancer research.Formula:C19H13Br2NO3Molecular weight:463.119CK2 inhibitor 2
CAS:CK2 Inhibitor 2, characterized as a potent, selective, and orally active inhibitor of CK2, demonstrates an impressive IC50 value of 0.66 nM.Formula:C21H17ClN4O2Purity:99.09%Color and Shape:SolidMolecular weight:392.84Ref: TM-T35557
1mg65.00€5mg145.00€10mg226.00€25mg449.00€50mg672.00€100mg900.00€200mg1,216.00€1mL*10mM (DMSO)160.00€ON 108600
CAS:ON 108600 is a chemical inhibitor targeting CK2 (Casein Kinase 2), TNIK, and DYRK1, demonstrating IC50 values of 0.016 μM and 0.007 μM for DYRK1A and DYRK1B, 0.Formula:C22H14Cl2N2O6S2Purity:98%Color and Shape:SolidMolecular weight:537.39CK1-IN-3
CAS:WAY-296817 inhibits CK1, potential for circadian rhythm and inflammation research.Formula:C17H16N2O3SPurity:98.70%Color and Shape:SolidMolecular weight:328.39Ref: TM-T60005
1mg48.00€5mg97.00€10mg145.00€25mg255.00€50mg368.00€100mg505.00€200mg692.00€1mL*10mM (DMSO)105.00€CKI-7 free base
CAS:CKI-7 free base is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 μM; Ki: 8.5 μM) and a selective Cdc7 kinase inhibitor.Formula:C11H12ClN3O2SColor and Shape:SolidMolecular weight:285.75p38α MAPK/CK1δ inhibitor-1
CAS:p38αMAPK/CK1δ inhibitor-1 (Compound 3) exhibits inhibitory activity against p38αMAPK and CK1δ, with IC50 values of 0.185 µM and 0.089 µM, respectively.Formula:C24H17FN6O2Color and Shape:SolidMolecular weight:440.429Casein kinase 1δ-IN-8
CAS:Casein kinase 1δ-IN-8 is an inhibitor of casein kinase 1δ and is used to treat neurodegenerative diseases such as Alzheimer's disease type.Formula:C19H14FN5OSPurity:99.66%Color and Shape:SolidMolecular weight:379.41
