Casein Kinase
Casein kinases are a family of serine/threonine protein kinases that regulate various cellular processes, including DNA repair, circadian rhythms, and signal transduction. These kinases are involved in the phosphorylation of numerous proteins and are implicated in diseases such as cancer, neurodegenerative disorders, and metabolic syndromes. At CymitQuimica, we offer a selection of casein kinase inhibitors to support your research in signal transduction, cell cycle regulation, and therapeutic development.
Products of "Casein Kinase"
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NMS-P715
CAS:NMS-P715 is a highly selective and ATP-competitive MPS1 inhibitor(IC50 of 182 nM).Formula:C35H39F3N8O3Purity:98.41%Color and Shape:SolidMolecular weight:676.73CK1δ-IN-10
CAS:CK1δ-IN-10 (Compound 85) is an inhibitor of casein kinase 1 (CK1), specifically targeting CK1δ (CSNKID), with an IC50 value of 0.255 μM.Formula:C17H11F4N5Color and Shape:SolidMolecular weight:361.296Casein kinase 1δ-IN-3
CAS:Casein kinase 1δ-IN-3 (Casein kinase 1δ-IN-3) (Compound 23a) is a casein kinase 1 delta (CK1d) inhibitor with a pIC50 of 6.5376 M.Formula:C17H16N2O2SPurity:99.42%Color and Shape:SoildMolecular weight:312.39Ref: TM-T64350
1mg38.00€5mg73.00€10mg115.00€25mg235.00€50mg373.00€100mg560.00€200mg797.00€1mL*10mM (DMSO)87.00€IC261
CAS:IC261 (SU-5607) is a novel inhibitor of CK1, triggers the mitotic checkpoint control. The IC50 of IC261 for CK1 was 16 μM and for Cdk5 is 4.5 mM.Formula:C18H17NO4Purity:99.47% - 99.91%Color and Shape:SolidMolecular weight:311.33CK1δ-IN-8
CAS:CK1δ-IN-8 (Compound 429) is a CK1δ inhibitor suitable for Alzheimer's disease research.Formula:C14H9N3O2S2Color and Shape:SolidMolecular weight:315.37LY294002
CAS:LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM).Formula:C19H17NO3Purity:98% - 99.96%Color and Shape:Pale Yellow SolidMolecular weight:307.34Longdaysin
CAS:Longdaysin is an inhibitor of CK1α and CK1δ (IC50s: 5.6/8.8 μM). It also can inhibit ERK2 (IC50: 52 μM).Formula:C16H16F3N5Purity:99.97%Color and Shape:SolidMolecular weight:335.33QXG-6442
QXG-6442 is a molecular glue degrader targeting CK1α, demonstrating a degradation potency with a DC50 of 5.7 nM and a Dmax of 90%. In the MOLM-14 cell line, QXG-6442 induces antiproliferative effects.Formula:C21H17N5O4Molecular weight:403.39TA-01
CAS:TA-01 is a potent CK1 and p38 MAPK inhibitor, with IC50s of 6.4 nM, 6.8 nM, 6.7 nM for CK1ε, CK1δ and p38 MAPK, respectively.Formula:C20H12F3N3Purity:98.77% - 99.94%Color and Shape:SolidMolecular weight:351.32Ref: TM-T4645
2mg35.00€5mg52.00€10mg85.00€25mg156.00€50mg235.00€100mg329.00€200mg464.00€1mL*10mM (DMSO)71.00€TAK-715
CAS:TAK-715 is a p38 MAPK inhibitor for p38α.Formula:C24H21N3OSPurity:99.69%Color and Shape:SolidMolecular weight:399.51Ref: TM-T6150
1mg40.00€2mg52.00€5mg87.00€10mg99.00€25mg170.00€50mg324.00€100mg507.00€1mL*10mM (DMSO)96.00€Casein kinase 1δ-IN-10
CAS:Casein kinase 1δ-IN-10 is an inhibitor of casein kinase 1δ (CK1δ).Formula:C21H17N3O3Purity:98%Color and Shape:SolidMolecular weight:359.38CK1δ-IN-5
CAS:CK1δ-IN-5 (Compound 24) is an inhibitor of casein kinase 1δ (CK1δ) and can be used in the study of neurodegenerative diseases.Formula:C22H21N5Color and Shape:SolidMolecular weight:355.436Silmitasertib
CAS:Silmitasertib (CX-4945) is a potent, orally bioavailable inhibitor of casein kinase 2 (CK2; Ki: 0.38 nM).Formula:C19H12ClN3O2Purity:98% - 99.90%Color and Shape:SolidMolecular weight:349.77Ref: TM-T2259
1mg40.00€2mg51.00€5mg85.00€10mg125.00€25mg207.00€50mg329.00€100mg520.00€500mg1,111.00€1mL*10mM (DMSO)93.00€D4476
CAS:D4476 (Casein Kinase I Inhibitor) is an effective, selective, and cell-permeant CK1 (casein kinase 1) inhibitor( IC50=300 nM in a cell-free assay).Formula:C23H18N4O3Purity:99.02% - 99.96%Color and Shape:SolidMolecular weight:398.41Ref: TM-T2449
1mg43.00€2mg55.00€5mg78.00€10mg95.00€25mg159.00€50mg226.00€100mg408.00€200mg597.00€500mg938.00€1mL*10mM (DMSO)86.00€Emodin
CAS:Emodin, a plant-derived anthraquinone, inhibits Y cell growth via various signaling pathways.Formula:C15H10O5Purity:94.4% - 98.9%Color and Shape:Physical Description Orange Needles Or Powder (Ntp 1992)Molecular weight:270.24PF-5006739
CAS:PF-5006739: potent, selective CK1δ/ε inhibitor (IC50: 3.9/17.0 nM); may treat psychiatric disorders, improves glucose tolerance, reduces opioid seeking.Formula:C22H22FN7OPurity:98%Color and Shape:SolidMolecular weight:419.45Epiblastin A
CAS:Epiblastin A inhibits CK1, targets its isoenzymes, and converts EpiSCs to cESCs.Formula:C12H10ClN7Purity:99.45%Color and Shape:SolidMolecular weight:287.71Casein kinase 1δ-IN-31
CAS:Casein kinase1δ-IN-31 (Compound 16) is an inhibitor of casein kinase (CK), specifically targeting CK1α, CK1δ, and p38α, with IC50 values of 196 nM, 17 nM, and 18 nM, respectively. Additionally, Casein kinase1δ-IN-31 inhibits Double Homeobox 4 (DUX4) with an IC50 of 1200 nM.Formula:C17H13FN4Color and Shape:SolidMolecular weight:292.31Casein kinase 1δ-IN-28
CAS:Casein kinase1δ-IN-28 (Compound 4) is an inhibitor of CK1ε, with an IC50 of 0.0146 μM. The human liver microsome metabolism rate for Casein kinase1δ-IN-28 is 52%.Formula:C23H23FN6Color and Shape:SolidMolecular weight:402.467CK2α-IN-1
CAS:CK2α-IN-1 is a selective non-ATP-competitive CK2α inhibitor with an IC50 of 7.0 µM and a Ki of 1.6 µM.CK2α-IN-1 exhibits potential anticancer activity and canFormula:C16H11N3O4SPurity:98.00%Color and Shape:SolidMolecular weight:341.34
