
PPAR
Peroxisome Proliferator-Activated Receptors (PPARs) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes involved in metabolism, particularly fatty acid storage and glucose metabolism. PPAR inhibitors are important tools for studying metabolic disorders such as diabetes, obesity, and cardiovascular diseases. These inhibitors can modulate lipid metabolism, insulin sensitivity, and inflammation, making them valuable in therapeutic research. At CymitQuimica, we offer a range of PPAR inhibitors to support your research in metabolic diseases, endocrinology, and drug development.
Products of "PPAR"
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Ankaflavin
CAS:Ankaflavin, from red rice fermentation, is a PPARγ agonist with anti-inflammatory properties and selectively kills cancer cells.Formula:C23H30O5Purity:98%Color and Shape:SolidMolecular weight:386.48Balaglitazone
CAS:Balaglitazone is a PPARγ agonist that regulates blood glucose and is used in studies of heart failure and myocardial infarction.Formula:C20H17N3O4SPurity:99.74%Color and Shape:SolidMolecular weight:395.43GW0742
CAS:GW0742 (GW610742) is an effective and specific PPARδ agonist (EC50: 1 nM/1.1 μM/2 μM, for human PPARδ/α/γ).Formula:C21H17F4NO3S2Purity:99.75% - 99.85%Color and Shape:SolidMolecular weight:471.49GW1929
CAS:GW1929 is a potent PPAR-γ agonist (pKi: 8.84 for human PPAR-γ; pEC50s of 8.56 and 8.27 for human and murine PPAR-γ).Formula:C30H29N3O4Purity:98.1% - 98.21%Color and Shape:SolidMolecular weight:495.57PPAR agonist 1
CAS:PPAR agonist 1 is an agonist of PPAR α/γ, used for reducing blood glucose, lipid levels, reducing body weight, and lowering cholesterol.Formula:C20H25NO6SPurity:98%Color and Shape:SolidMolecular weight:407.48Tetradecylthioacetic acid
CAS:Synthetic fatty acid TTA has β-sulfur, resists β-oxidation, and activates PPARs, especially PPARα.Formula:C16H32O2SPurity:≥98%Color and Shape:SolidMolecular weight:288.49Ref: TM-T9808
5mg47.00€10mg70.00€25mg111.00€50mg170.00€100mg264.00€200mg398.00€500mg647.00€1mL*10mM (DMSO)50.00€Angeloylgomisin H
CAS:Angeloylgomisin H shows moderate cytotoxic activities with IC50 values ranging from 100 to 200 ug/mL against MCF7, HEK293 and CAL27 cell lines.Formula:C28H36O8Purity:97.23% - 99.95%Color and Shape:SolidMolecular weight:500.58Ref: TM-TN1018
1mg55.00€5mg117.00€10mg182.00€25mg306.00€50mg444.00€100mg610.00€1mL*10mM (DMSO)158.00€Bocidelpar
CAS:Bocidelpar is a modulator of PPARδ with an EC50 of 7.80 nM and improves mitochondrial biogenesis and function in Duchenne Muscular Dystrophy muscle cells.Formula:C25H27F3N2O3Purity:98.05%Color and Shape:SolidMolecular weight:460.49Ref: TM-T39516
1mg120.00€5mg274.00€10mg411.00€25mg742.00€50mg1,111.00€100mg1,549.00€1mL*10mM (DMSO)279.00€Anti-NASH agent 1
CAS:Anti-NASH Agent 1 (Compound 3d), derived from Elafibranor, serves as a strong PPAR-α/δ agonist aimed at treating nonalcoholic steatohepatitis (NASH).Formula:C26H33NO4Purity:98%Color and Shape:SolidMolecular weight:423.54GSK0660
CAS:GSK0660 is an antagonist and inverse agonist of PPARβ/δ.Formula:C19H18N2O5S2Purity:100% - ≥95%Color and Shape:SolidMolecular weight:418.49Ref: TM-T2674
2mg47.00€5mg69.00€10mg104.00€25mg185.00€50mg369.00€100mg548.00€500mg1,198.00€1mL*10mM (DMSO)69.00€Fenofibrate
CAS:Fenofibrate (Lipanthyl) is a PPARα agonist. Fenofibrate inhibits cytochrome P450 isoforms. Fenofibrate exhibits antihyperlipidemic activity. Cost-effective and quality-assured.Formula:C20H21ClO4Purity:99.13% - 99.95%Color and Shape:Crystals From Isopropanol SolidMolecular weight:360.83SP4e
SP4e is a PPAR-γ activator.SP4e was effective in decreasing blood glucose, total cholesterol, triglycerides and LDL levels and increasing HDL levels.Formula:C22H17ClN2O2S2Purity:99.79%Color and Shape:SoildMolecular weight:440.97Retinoic acid
CAS:Retinoic acid (Tretinoin) binds to and activates RARs, thereby inducing changes in gene expression that lead to inhibition of tumorigenesis.Formula:C20H28O2Purity:97.21% - 99.6%Color and Shape:Yellow-Orange PowderMolecular weight:300.44GQ-16
CAS:GQ-16 is a partial agonist of PPARγ with a Ki of 160 nM. GQ-16 reduces adipogenic actions and promotes insulin Sensitization without weight gain.Formula:C19H16BrNO3SPurity:99.12%Color and Shape:SolidMolecular weight:418.3Lonazolac
CAS:Lonazolac is a nonsteroidal anti-inflammatory drug[1].Formula:C17H13ClN2O2Purity:99.40%Color and Shape:SolidMolecular weight:312.75Ref: TM-T50025
5mg57.00€10mg86.00€25mg131.00€50mg188.00€100mg284.00€200mg426.00€1mL*10mM (DMSO)74.00€Cevoglitazar
CAS:Cevoglitazar (LBM-642) is a PPARɑ agonist and PPARγ agonist. Cevoglitazar potently reduces food intake and body weight in obese mice and cynomolgus monkeys.Formula:C27H21F3N2O6SPurity:97.39%Color and Shape:SolidMolecular weight:558.53Mifobate
CAS:Mifobate (SR-202) 是一种有效且特异性的 PPARγ拮抗剂,可选择性抑制噻唑烷二酮 (TZD) 诱导的 PPARγ 转录活性,IC50为140 μM,具有抗肥胖和抗糖尿病作用。Formula:C11H17ClO7P2Purity:99.12%Color and Shape:SolidMolecular weight:358.65Ref: TM-T16074
1mg52.00€5mg111.00€10mg180.00€25mg303.00€50mg449.00€100mg645.00€1mL*10mM (DMSO)124.00€Cinnamyl alcohol
CAS:Cinnamyl alcohol (Styryl Carbinol) readily autoxidizes upon air exposure, and forms strong sensitizers as determined by the local lymph node assay.Formula:C9H10OPurity:99.00%Color and Shape:Colourless LiquidMolecular weight:134.18Fonadelpar
CAS:Fonadelpar is an agonist of PPARδ. It also is used in the research of neuroparalytic keratopathy.Formula:C25H23F3N2O4SPurity:98%Color and Shape:SolidMolecular weight:504.52GW6471
CAS:GW6471 is an antagonist of PPARα. GW6471 enhances the binding affinity of the PPAR α ligand-binding domain to the co-repressor proteins SMRT and NCoR.Formula:C35H36F3N3O4Purity:98.23% - 99.55%Color and Shape:SolidMolecular weight:619.67Ref: TM-T8486
1mg38.00€5mg80.00€10mg105.00€25mg215.00€50mg426.00€100mg623.00€500mg1,293.00€1mL*10mM (DMSO)120.00€