
Phospholipase
Phospholipases are a group of enzymes that hydrolyze phospholipids into fatty acids and other lipophilic substances, playing a critical role in membrane biology and the generation of signaling molecules. Inhibitors of phospholipases are used to study their role in inflammatory diseases, cardiovascular disorders, and neurodegeneration. These inhibitors are also valuable in exploring lipid signaling pathways and their implications in disease mechanisms. At CymitQuimica, we provide a variety of phospholipase inhibitors to support your research in inflammation, lipid metabolism, and cell signaling.
Products of "Phospholipase"
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trans-Benzylideneacetone
CAS:trans-Benzylideneacetone (Acetocinnamone) is used in various synthetic preparations.Formula:C10H10OPurity:97.48%Color and Shape:Light Yellow Low Melting Crystalline MassMolecular weight:146.19Aristolochic acid C
CAS:Aristolochic acid C is a derivative of Aristolochic acid which is a phospholipase A2 inhibitor.Formula:C16H9NO7Purity:98.14%Color and Shape:White PowderMolecular weight:327.25Carbazochrome
CAS:Carbazochrome (Adchnon) is an antihemorrhagic that promotes platelet aggregation to stop bleeding, possibly for surgeries and hemorrhoids treatment.Formula:C10H12N4O3Purity:98.36%Color and Shape:Nacarat Crystalline PowderMolecular weight:236.23Fuzapladib
CAS:Fuzapladib (IS-741) is a PLA2 inhibitor that reduces Mac-1 expression to prevent inflammation and pancreatitis.Formula:C15H20F3N3O3SPurity:99.65%Color and Shape:SoildMolecular weight:379.4Tris(2,4-di-tert-butylphenyl)phosphate
CAS:Tris(2,4-di-tert-butylphenyl)phosphate (TDTBPP) inhibits secretory phospholipase A2 (sPLA2) with anti-inflammatory effect. Cost-effective and quality-assured.Formula:C42H63O4PPurity:99.73%Color and Shape:SolidMolecular weight:662.92ML299
CAS:ML299 (VU0463568) is a dual PLD1/2 inhibitor (PLD1 and PLD2, IC50 of 6 nM, 20 nM, respectively).Formula:C23H26BrFN4O2Purity:98%Color and Shape:SolidMolecular weight:489.38ML-211
CAS:ML-211 is a carbamate-based dual inhibitor of LYPLA1 (IC50 = 17 nM) and the related LYPLA2 (IC50 = 30 nM)Formula:C25H30N4O2Purity:97.07%Color and Shape:SolidMolecular weight:418.53BAPTA
CAS:BAPTA is a neuroprotective agent in cerebral ischemia, acting as an intercellular Ca2+ chelator.Formula:C22H24N2O10Purity:96.28% - ≥95%Color and Shape:White SolidMolecular weight:476.43LCL521
CAS:LCL521 inhibits lysosomal acid sphingomyelinase (ASMase).LCL521 is an acid ceramidase (ACDase) inhibitor.Formula:C31H52N4O7Purity:98%Color and Shape:SolidMolecular weight:592.77ML348
CAS:ML348 (GNF-Pf-1127) is a selective and reversible lysophospholipase 1 (LYPLA1) inhibitor (IC50 = 210 nM).Formula:C18H17ClF3N3O3Purity:99% - 99.88%Color and Shape:SolidMolecular weight:415.79Ref: TM-T3439
2mg47.00€5mg69.00€10mg97.00€25mg227.00€50mg354.00€100mg567.00€200mg792.00€500mg1,198.00€AACOCF3
CAS:AACOCF3 (Arachidonyl trifluoromethyl ketone) is a cell-permeable trifluoromethyl ketone analog of arachidonic acid.Formula:C21H31F3OPurity:99% - 99%Color and Shape:Yellow LiquidMolecular weight:356.473-Nitrocoumarin
CAS:3-Nitrocoumarin (3-nitrochromen-2-one) (3-NC) is a potent and selective Phospholipase C-γ (PLCγ) inhibitor.Formula:C9H5NO4Purity:97.28%Color and Shape:SolidMolecular weight:191.14U-73343
CAS:U-73343 is an inactive analog of U-73122 and can be used as a negative control. U-73122 dose-dependently inhibits acid secretion irrespective of the stimulant.Formula:C29H42N2O3Purity:99.06%Color and Shape:SolidMolecular weight:466.66GK187
CAS:GK187 is a selective and potent Group VIA calcium-independent phospholipase A2 (GVIA iPLA2) inhibitor, used in the study of neurological disorders.Formula:C14H15F5O2Color and Shape:SolidMolecular weight:310.26Ref: TM-T37221
1mg87.00€5mg183.00€10mg296.00€25mg565.00€50mg909.00€100mg1,444.00€200mg1,882.00€1mL*10mM (DMSO)202.00€Lp-PLA2-IN-16
CAS:Lp-PLA2-IN-16 (Example 1) is an inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2) with potential applications in Alzheimer's disease research [1].Formula:C22H17F5N4O3Purity:98%Color and Shape:SolidMolecular weight:480.39Columbin
CAS:Columbin: anti-inflammatory, prevents colon cancer, inhibits PLA2 in RBC dose-dependently.Formula:C20H22O6Purity:99.34% - 99.74%Color and Shape:SolidMolecular weight:358.39Lp-PLA2-IN-12
CAS:Lp-PLA2-IN-12 (compound 19), an Lp-PLA2 inhibitor, is utilized in researching neurodegenerative diseases including Alzheimer's disease (AD), glaucoma, age-Formula:C24H23F2N5O3Purity:98%Color and Shape:SolidMolecular weight:467.47Rhamnetin
CAS:Rhamnetin (beta-Rhamnocitrin), a quercetin derivative found in Coriandrum sativum, has antioxidant and anti-inflammatory activities.Formula:C16H12O7Purity:97.6%Color and Shape:SolidMolecular weight:316.26Omeprazole
CAS:Omeprazole (Losec) is a proton pump inhibitor (PPI), Omeprazole(Losec) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor.Formula:C17H19N3O3SPurity:98.43% - 98.48%Color and Shape:White SolidMolecular weight:345.42LEI110
CAS:LEI110 inhibits PLA2G16 and HRASLS enzymes, Ki 20 nM, selectively targets related thiol hydrolases.Formula:C25H23F3N2O3Purity:97.56% - 98.8%Color and Shape:SolidMolecular weight:456.46