
Cyclooxygenase (COX) Inhibitors
Cyclooxygenase (COX) inhibitors are compounds that block the activity of COX enzymes, which are involved in the production of prostaglandins, key mediators of inflammation and pain. In neuroscience, COX inhibitors are studied for their potential to reduce neuroinflammation, which is implicated in various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By inhibiting COX, these compounds may help mitigate inflammatory processes in the brain and protect against neuronal damage. At CymitQuimica, we provide a range of COX inhibitors to support your research in neuroinflammation, pain management, and neurodegenerative disease.
Products of "Cyclooxygenase (COX) Inhibitors"
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CAFESTOL
CAS:Cafestol, an ERK inhibitor, suppresses PGE2 and COX-2 by blocking NF-kB in LPS-stimulated RAW264.7 cells.Formula:C20H28O3Purity:97.06% - 99.08%Color and Shape:SolidMolecular weight:316.432,3'-Bipyridine, 5-chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]-
CAS:Formula:C18H15ClN2O2SPurity:98%Color and Shape:SolidMolecular weight:358.8419Lumiracoxib
CAS:Lumiracoxib (Prexige) is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. Phase 4.Formula:C15H13ClFNO2Purity:96.64% - 99.25%Color and Shape:Pale Yellow SolidMolecular weight:293.72NS-398
CAS:NS-398 (N-(2-cyclohexyloxy-4-nitrophenyl)methane sulfonamide) is a COX-2 inhibitor wih anti-inflammatory activity.Formula:C13H18N2O5SPurity:99% - 99.72%Color and Shape:SolidMolecular weight:314.36Ref: TM-T3214
2mg35.00€5mg50.00€10mg66.00€25mg96.00€50mg177.00€100mg274.00€200mg355.00€1mL*10mM (DMSO)56.00€5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol
CAS:Formula:C14H12O3Purity:98%Color and Shape:SolidMolecular weight:228.24328Meloxicam
CAS:Meloxicam (Metacam) is a Nonsteroidal Anti-inflammatory Drug.Formula:C14H13N3O4S2Purity:97.09% - 99.60%Color and Shape:Light Yellow SolidMolecular weight:351.4Esculentoside A
CAS:Esculentoside A dampens inflammation in ALI, modulates T cells, and could treat autoimmune diseases and BXSB mice by adjusting cytokines and renal cells.Formula:C42H66O16Purity:98% - 99.85%Color and Shape:SolidMolecular weight:826.96MECLOFENAMATE SODIUM
CAS:Formula:C14H11Cl2NNaO2Purity:99%Color and Shape:SolidMolecular weight:319.1384γ-Tocopherol
CAS:(+)-γ-Tocopherol ((+)-γ-Tocopherol) is one of the naturally occurring forms of Vitamin E. It is the most abundant Tocopherol in soybean and corn oils.Formula:C28H48O2Purity:99.31% - 99.39%Color and Shape:Clear Viscous Pale Yellow Oil Which Oxidises And Darkens On Exposure To Air Or LightMolecular weight:416.68Indomethacin
CAS:Formula:C19H16ClNO4Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:357.79(S)-(+)-2-(6-Methoxy-2-naphthyl)propionic Acid
CAS:Formula:C14H14O3Purity:>99.0%(GC)(T)Color and Shape:White to Almost white powder to crystalMolecular weight:230.26Isofraxidin
CAS:Isofraxidin combats leukemia, ALI, and inflammation by modulating ROS, COX-2, PGE2, TNF-α, and p38/ERK1/2 pathways.Formula:C11H10O5Purity:99.51% - ≥95%Color and Shape:SolidMolecular weight:222.19Ketorolac tromethamine salt
CAS:Ketorolac tromethamine salt (Ketorolac tris salt) non-selective inhibits the enzymes cyclooxygenase 1 (COX-1) and COX-2with anti-inflammatory, analgesic, andFormula:C19H24N2O6Purity:99.48% - 99.85%Color and Shape:CrystallineMolecular weight:376.42,5-Di-tert-butylhydroquinone
CAS:2,5-Di-tert-butylhydroquinone (BHQ) is an effective and selective endoplasmic reticulum Ca2+-ATPase inhibitor.Formula:C14H22O2Purity:97.11%Color and Shape:PelletslargecrystalsMolecular weight:222.32Apyramide
CAS:Apyramide, an NSAID and prodrug of indomethacin, inhibits COX1/COX2 and permeates the blood-brain barrier.Formula:C27H23ClN2O5Purity:98.99%Color and Shape:SolidMolecular weight:490.93Ref: TM-T10355
1mg35.00€5mg65.00€10mg101.00€25mg170.00€50mg248.00€100mg338.00€200mg460.00€1mL*10mM (DMSO)90.00€SC-75416
CAS:SC-75416, a cyclooxygenase-2 (COX-2) inhibitor, is used potentially for the treatment of postoperative inflammation.Formula:C15H14ClF3O3Purity:98.67% - 98.67%Color and Shape:SolidMolecular weight:334.72Ibuprofen
CAS:Ibuprofen, an NSAID, reduces pain, inflammation, and fever by limiting prostaglandin production.Formula:C13H18O2Purity:99.7% - 99.81%Color and Shape:Colorless Solid CrystallineMolecular weight:206.28Tolmetin
CAS:Formula:C15H15NO3Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:257.29