Cyclooxygenase (COX) Inhibitors
Cyclooxygenase (COX) inhibitors are compounds that block the activity of COX enzymes, which are involved in the production of prostaglandins, key mediators of inflammation and pain. In neuroscience, COX inhibitors are studied for their potential to reduce neuroinflammation, which is implicated in various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By inhibiting COX, these compounds may help mitigate inflammatory processes in the brain and protect against neuronal damage. At CymitQuimica, we provide a range of COX inhibitors to support your research in neuroinflammation, pain management, and neurodegenerative disease.
Products of "Cyclooxygenase (COX) Inhibitors"
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Fenoprofen Calcium Salt Dihydrate
CAS:Formula:C30H26CaO6·2H2OPurity:>98.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:558.64Acemetacin
CAS:Formula:C21H18ClNO6Purity:>98.0%(GC)(T)Color and Shape:Light yellow to Yellow to Green powder to crystalMolecular weight:415.83STAT1/3-IN-1
CAS:STAT1/3-IN-1 (Compound 6k) is an inhibitor of STAT1/3 phosphorylation. It prevents the phosphorylation and nuclear translocation of STAT1/3. Additionally, STAT1/3-IN-1 inhibits the inflammatory enzymes iNOS and COX-2. This compound exhibits anti-inflammatory properties by reducing pro-inflammatory cytokines, such as IL-1β, IL-6, and TNF-α, without significant cytotoxicity.Formula:C28H25ClN6O5Color and Shape:SolidMolecular weight:560.988Metamizole sodium
CAS:Metamizole sodium (Analgin) is a drug that has analgesic, anti-inflammatory, and antipyretic properties. It is the sodium sulfonate of AMINOPYRINE.Formula:C13H16N3NaO4SPurity:99.52%Color and Shape:White Or Almost White Crystal PowderMolecular weight:333.34Tenidap
CAS:Tenidap (CP-66248) is a selective COX-1 and SLC26A3 inhibitor with anti-inflammatory, analgesic, and anti-rheumatic activities.Formula:C14H9ClN2O3SPurity:98.36% - 99.42%Color and Shape:SolidMolecular weight:320.75Indoprofen
CAS:Indoprofen ((±)-Indoprofe) is a non-steroidal anti-inflammatory drug.Formula:C17H15NO3Purity:100%Color and Shape:SolidMolecular weight:281.31Nabumetone
CAS:Nabumetone (BRL14777)(BRL14777) is a non-steroidal anti-inflammatory drug and its active metabolite 6MNA inhibits the enzymes cyclo-oxygenase I and II.Formula:C15H16O2Purity:97.59% - 99.61%Color and Shape:White /Almost White Crystalline PowderMolecular weight:228.29Cis-5-Dodecenoic Acid
CAS:Cis-5-Dodecenoic Acid is a monounsaturated fatty acid that has a C12 chain as a backbone and a cis double bond at the C5 position.Formula:C12H22O2Purity:98% - 99.37%Color and Shape:SolidMolecular weight:198.3Paradol
CAS:Paradol, a spicy compound in ginger, offers anti-cancer, anti-inflammatory, antioxidant, and neuroprotective benefits.Formula:C17H26O3Purity:98.65% - 98.98%Color and Shape:SolidMolecular weight:278.39Floctafenine
CAS:Floctafenine (R-4318) is a non-steroidal anti-inflammatory compound that is a COX-I and COX-2 inhibitor with analgesic activity for the study of pain.Formula:C20H17F3N2O4Purity:98.65%Color and Shape:SolidMolecular weight:406.36Fenofibric acid
CAS:Fenofibric acid (FNF acid) is the active form of fenofibrate, a synthetic phenoxy-isobutyric acid derivate with antihyperlipidemic activity.Formula:C17H15ClO4Purity:99.36%Color and Shape:White Or Almost White Crystalline PowderMolecular weight:318.75Harpagoside
CAS:Harpagoside: anti-inflammatory; 3 mM inhibits seed germination; reduces COX-2, iNOS mRNA, and protein in HepG2.Formula:C24H30O11Purity:100% - ≥95%Color and Shape:White To Off-White PowderMolecular weight:494.49Phenylbutazone
CAS:Phenylbutazone, an anti-inflammatory, reduces fever and pain, used for spondylitis and arthritis.Formula:C19H20N2O2Purity:99.70%Color and Shape:SolidMolecular weight:308.37Guaiacol
CAS:Guaiacol, a flavorant precursor, has medicinal uses and serves as an oxygen indicator turning yellow-brown at 470 nm.Formula:C7H8O2Purity:99.83%Color and Shape:Colourless To Pale Yellow Solid CrystallineMolecular weight:124.14Nitroflurbiprofen
CAS:Nitroflurbiprofen (Nitroxybutyl flurbiprofen) is a NO-releasing COX inhibitor and modulates the increased intrahepatic vascular tone in portal hypertensiveFormula:C19H20FNO5Purity:99.38%Color and Shape:SolidMolecular weight:361.36Ref: TM-T16329
1mg85.00€5mg164.00€10mg245.00€25mg419.00€50mg562.00€100mg792.00€200mg1,064.00€1mL*10mM (DMSO)170.00€Tolfenamic Acid
CAS:Formula:C14H12ClNO2Purity:>97.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:261.71Sudoxicam
CAS:Sudoxicam (4-Hydroxy-2-methyl-N-2-thiazolyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide) is a reversible antagonist of COX with anti-inflammatory, anti-edemaFormula:C13H11N3O4S2Purity:100%Color and Shape:SolidMolecular weight:337.37Ref: TM-T16950
2mg42.00€5mg64.00€10mg97.00€25mg183.00€50mg284.00€100mg411.00€200mg585.00€1mL*10mM (DMSO)64.00€Methyl 2-(2,6-Dichloroanilino)phenylacetate
CAS:Formula:C15H13Cl2NO2Purity:>97.0%(GC)(N)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:310.17Loxoprofen
CAS:Loxoprofen (Koloxo) is an anti-inflammatory non-steroidal medicine.Formula:C15H18O3Purity:98.25%Color and Shape:White To Yellowish Crystalline PowderMolecular weight:246.3Ref: TM-T0463
1g155.00€10mg34.00€25mg44.00€50mg47.00€100mg59.00€200mg71.00€500mg104.00€1mL*10mM (DMSO)34.00€anemarsaponin B
CAS:Anemarsaponin B has anti-inflammatory effect in LPS-treated RAW 264.7macrophages, the effect is associated with the inhibition of NF-κB transcriptional activityFormula:C45H74O18Purity:99.06% - 99.81%Color and Shape:SolidMolecular weight:903.06
