Cyclooxygenase (COX) Inhibitors
Cyclooxygenase (COX) inhibitors are compounds that block the activity of COX enzymes, which are involved in the production of prostaglandins, key mediators of inflammation and pain. In neuroscience, COX inhibitors are studied for their potential to reduce neuroinflammation, which is implicated in various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By inhibiting COX, these compounds may help mitigate inflammatory processes in the brain and protect against neuronal damage. At CymitQuimica, we provide a range of COX inhibitors to support your research in neuroinflammation, pain management, and neurodegenerative disease.
Products of "Cyclooxygenase (COX) Inhibitors"
Sort by
COX-1-IN-2
COX-1-IN-2 (compound 5h) serves as a potent anti-inflammatory and analgesic agent. This compound demonstrates a significant inhibitory effect on COX-1, with an IC 50 value of 38.76 nM.Formula:C29H22FN3OSColor and Shape:SolidMolecular weight:479.57Niflumic acid
CAS:Formula:C13H9F3N2O2Purity:98%Color and Shape:SolidMolecular weight:282.21796959999995Prim-O-glucosylcimifugin
CAS:Prim-O-glucosylcimifugin (Cimifugin 7-glucoside) can inhibit the proliferation of SMC stimulated by TNF-alpha, increase the proportion of G0/G1 phase.Formula:C22H28O11Purity:98.57% - 99.92%Color and Shape:SolidMolecular weight:468.45Benzenesulfonamide, 4-(5-methyl-3-phenyl-4-isoxazolyl)-
CAS:Formula:C16H14N2O3SPurity:%Color and Shape:SolidMolecular weight:314.35895999999997(S)-(+)-Ibuprofen
CAS:Formula:C13H18O2Purity:>98.0%(GC)(T)Color and Shape:White to Almost white powder to crystalMolecular weight:206.29COX-2-IN-47
CAS:COX-2-IN-47 (compound 6c) is a selective inhibitor of COX-2, exhibiting an IC50 of 0.03 μM. This compound also displays antiedema activity.Formula:C18H18N2O4Color and Shape:SolidMolecular weight:326.35α-Demethylnaproxen
CAS:α-Demethylnaproxen is a competitive inhibitor of COX(Ki values of 21 and 19 μM for ovine COX-1 and -2, respectively)Formula:C13H12O3Purity:97.57%Color and Shape:Off-White SolidMolecular weight:216.23SC-236
CAS:SC-236 (Sc 236) is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 μM and 17.8 μM for COX-2 and COX-1, respectively).Formula:C16H11ClF3N3O2SPurity:99.74%Color and Shape:SolidMolecular weight:401.79Mefenamic acid
CAS:Mefenamic acid (CN-35355) is a non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties.Formula:C15H15NO2Purity:99.32%Color and Shape:Crystals SolidMolecular weight:241.29Naproxen
CAS:Naproxen ((S)-Naproxen) is a propionic acid derivative and a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, antipyretic and analgesicFormula:C14H14O3Purity:99.6% - 99.89%Color and Shape:Crystals From Acetone-Hexane SolidMolecular weight:230.26(-)-Catechin gallate
CAS:(-)-Catechin gallate inhibits 6PGD, IDH, Beta-secretase, and fights chloroquine-sensitive/resistant Plasmodium falciparum.Formula:C22H18O10Purity:100% - 97.74%Color and Shape:SolidMolecular weight:442.37FR 122047
CAS:FR 122047 (1-[(4,5-Bis(4-methoxyphenyl-2-thiazoyl)carbonyl]-4-methylpiperazine, Hydrochloride) is a potent and selective inhibitor of COX-1 with IC50 of 28 nMFormula:C23H26ClN3O3SPurity:99.63%Color and Shape:SolidMolecular weight:459.99Sulindac
CAS:Formula:C20H17FO3SPurity:>98.0%(T)(HPLC)Color and Shape:Light yellow to Brown powder to crystalMolecular weight:356.41Pectolinarigenin
CAS:Pectolinarigenin has hepatoprotective and anti-inflammatory properties, acting through SOD and inhibiting eicosanoids.Formula:C17H14O6Purity:98.67% - 98.77%Color and Shape:SolidMolecular weight:314.29Ref: TM-T6S0413
1mg48.00€5mg95.00€10mg162.00€25mg280.00€50mg432.00€100mg653.00€1mL*10mM (DMSO)116.00€Bromfenac Sodium Sesquihydrate
CAS:Formula:C15H11BrNaNO3H2OPurity:>98.0%(T)(HPLC)Color and Shape:White to Yellow powder to crystalMolecular weight:383.17Propanedinitrile,2-[(4-methoxyphenyl)methylene]-
CAS:Formula:C11H8N2OPurity:98%Color and Shape:SolidMolecular weight:184.194(-)-Ibuprofenamide
CAS:(-)-Ibuprofenamide is an amide prodrug of Ibuprofen with anti-inflammatory activity.Formula:C13H19NOPurity:98%Color and Shape:SolidMolecular weight:205.32-Ethoxybenzamide
CAS:2-Ethoxybenzamide (Anovigam) is white or almost-white crystalline powder. Almost odorless. Tasteless. It is widely used as an antipyretic anodyne.Formula:C9H11NO2Purity:99.75%Color and Shape:1992)Molecular weight:165.19Tolfenamic Acid
CAS:Tolfenamic Acid (GEA 6414) is one of the class of non-steroidal anti-inflammatory drugs (NSAIDs). It is used to treat the symptoms of migraine.Formula:C14H12ClNO2Purity:99.71% - 99.97%Color and Shape:SolidMolecular weight:261.7Hamaline
CAS:Hamaline (9-(4-chlorobenzyl)-6-methoxy-1-methyl-4,9-dihydro-3H-pyrido[3,4-b]indole) is a substrate-selective cyclooxygenase-2 (COX-2) inhibitor.Formula:C20H19ClN2OPurity:99.88%Color and Shape:SoildMolecular weight:338.83Ref: TM-T60053
1mg38.00€5mg72.00€10mg93.00€25mg150.00€50mg213.00€100mg320.00€200mg457.00€1mL*10mM (DMSO)77.00€
![Propanedinitrile,2-[(4-methoxyphenyl)methylene]-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb-webp%2FDA007L0Q.webp&w=3840&q=75)
