
Cyclooxygenase (COX) Inhibitors
Cyclooxygenase (COX) inhibitors are compounds that block the activity of COX enzymes, which are involved in the production of prostaglandins, key mediators of inflammation and pain. In neuroscience, COX inhibitors are studied for their potential to reduce neuroinflammation, which is implicated in various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By inhibiting COX, these compounds may help mitigate inflammatory processes in the brain and protect against neuronal damage. At CymitQuimica, we provide a range of COX inhibitors to support your research in neuroinflammation, pain management, and neurodegenerative disease.
Products of "Cyclooxygenase (COX) Inhibitors"
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Madecassic acid
CAS:Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.Formula:C30H48O6Purity:98.80% - 99.69%Color and Shape:SolidMolecular weight:504.7Pemedolac
CAS:Pemedolac (Dexpemedolac) is a small molecule COX inhibitor used to treat neurological disorders, skin and musculoskeletal disorders.Formula:C22H23NO3Purity:100%Color and Shape:SolidMolecular weight:349.42syringaldehyde
CAS:Syringaldehyde is a polyphenolic compound belonging to the group of flavonoids and is found in different plant species, moderately inhibiting COX-2 activity.Formula:C9H10O4Purity:99.24%Color and Shape:Light Yellow-Green To Brown Crystalline PowderMolecular weight:182.17Ampiroxicam
CAS:Ampiroxicam (Flucam) is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug.Formula:C20H21N3O7SPurity:97.27% - 99.2%Color and Shape:PowderMolecular weight:447.46Adelmidrol
CAS:Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.Formula:C13H26N2O4Purity:99.35% - 99.73%Color and Shape:SolidMolecular weight:274.36Neral
CAS:Neral, a monoterpenoid compound, exhibits anti-inflammatory and anticancer activities. It inhibits TNF-α and IL-6, along with inflammatory mediators such as pro-IL-1β, iNOS, COX-2, and NLRP-3.Formula:C10H16OColor and Shape:SolidMolecular weight:152.23S-(+)-Marmesin
CAS:S-(+)-Marmesin (marmesin) is a coumarin originally isolated from the mature bark of A. marmelos,exhibiting COX-2/5-LOX dual inhibitory activity.Formula:C14H14O4Purity:98.00% - ≥98%Color and Shape:SolidMolecular weight:246.26Ibuprofen Lysine
CAS:Ibuprofen Lysine (Neoprofen) is a non-steroidal anti-inflammatory drug.Formula:C19H32N2O4Purity:99.66%Color and Shape:CoaMolecular weight:352.47Carprofen
CAS:Formula:C15H12ClNO2Purity:>98.0%(T)(HPLC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:273.72Flunixin meglumine
CAS:Flunixin meglumine (Banamine) is an effective inhibitor of the enzyme cyclooxygenase with anti-inflammatory and antipyretic activity.Formula:C21H28F3N3O7Purity:100% - 99.86%Color and Shape:SolidMolecular weight:491.46COX-2-IN-46
COX-2-IN-46 (compound 5m) serves as a potent anti-inflammatory and analgesic agent. It demonstrates a significant inhibitory action on COX-2, with an IC 50 value of 87.74 nM.Formula:C28H19F2N3SColor and Shape:SolidMolecular weight:467.53DuP-697
CAS:DuP-697 is an irreversible, specific COX-2 inhibitor with IC50 values of 10 nM and 800 nM for human COX-2 and COX-1.Cost-effective and quality-assured.Formula:C17H12BrFO2S2Purity:100%Color and Shape:SolidMolecular weight:411.31Ref: TM-T15181
1mg52.00€5mg104.00€10mg154.00€25mg249.00€50mg369.00€100mg543.00€200mg772.00€1mL*10mM (DMSO)124.00€Butyl 2-[[3-(Trifluoromethyl)phenyl]amino]benzoate
CAS:Formula:C18H18F3NO2Purity:>98.0%(HPLC)(N)Color and Shape:Colorless to Yellow clear liquidMolecular weight:337.34Diclofenac Sodium Salt
CAS:Formula:C14H10Cl2NNaO2Purity:98%Color and Shape:SolidMolecular weight:318.13052-O-Sinapoyl makisterone A
Compound 2, formally known as 2-O-Sinapoyl makisterone A, is a sinapinic acid-ecdysterone hybrid that acts as a selective inhibitor of COX-2, effectivelyFormula:C39H56O11Purity:98%Color and Shape:SolidMolecular weight:700.86Tepoxalin
CAS:Tepoxalin (RWJ 20485), potential asthma and osteoarthritis drug, inhibits COX-1, COX-2, and 5-LOX with low IC50 values.Formula:C20H20ClN3O3Purity:99.03%Color and Shape:SolidMolecular weight:385.84Ref: TM-T7724
1mg56.00€5mg119.00€10mg170.00€25mg393.00€50mg587.00€100mg835.00€200mg1,130.00€1mL*10mM (DMSO)139.00€Byakangelicol
CAS:Byakangelicol may reduce P-gp at BBB and has anti-inflammatory effects by hindering COX-2 and PGE2 in A549 cells.Formula:C17H16O6Purity:99.15% - 99.55%Color and Shape:SolidMolecular weight:316.31Salicylic acid
CAS:Salicylic acid (2-Hydroxybenzoic acid), a natural compound extracted from Willow bark, is an anti-inflammatory inhibitor of activity cyclooxygenase.Formula:C7H6O3Purity:98.04% - 98.83%Color and Shape:White Solid PowderMolecular weight:138.12RHC 80267
CAS:RHC 80267 (U-57908) is a selective inhibitor of DAGL (IC50 : 4 μM in canine platelets)Formula:C20H34N4O4Purity:99.54%Color and Shape:White SolidMolecular weight:394.51