AChR
Acetylcholine Receptor (AChR) inhibitors are compounds that block the activity of acetylcholine receptors, which are critical for neurotransmission in the central and peripheral nervous systems. AChRs play a vital role in muscle contraction, memory, and cognitive functions. Inhibitors of AChRs are used to study conditions such as myasthenia gravis, Alzheimer's disease, and other neurological disorders. By modulating AChR activity, these inhibitors can help unravel the complexities of cholinergic signaling in the brain. At CymitQuimica, we provide a range of AChR inhibitors to support your research in neuroscience, pharmacology, and neurodegenerative disease.
Products of "AChR"
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Clothianidin
CAS:Clothianidin (TI 435), an insecticide, stimulates nAChR as acetylcholine agonist, not AChE inhibitor.Formula:C6H8ClN5O2SPurity:99.71%Color and Shape:Solid PowderMolecular weight:249.68Tropicamide
CAS:Tropicamide (Ro 1-7683), a synthetic atropine-like muscarinic antagonist, dilates pupils and paralyzes eye muscles for diagnostic use.Formula:C17H20N2O2Purity:99.78% - 99.94%Color and Shape:White PowderMolecular weight:284.35Glycopyrrolate
CAS:Glycopyrrolate: muscarinic antagonist, antispasmodic for GI issues, reduces salivation with anesthesia.Formula:C19H28BrNO3Purity:99.41% - 99.64%Color and Shape:SolidMolecular weight:398.33PNU-282987 S enantiomer free base
CAS:PNU-282987 S enantiomer free base is an agonist of α7 nicotinic acetylcholine receptor (α7 nAChR).Formula:C14H17ClN2OPurity:99.74%Color and Shape:SolidMolecular weight:264.75Ref: TM-T7695
1mg97.00€5mg235.00€10mg329.00€25mg509.00€50mg695.00€100mg940.00€200mg1,264.00€1mL*10mM (DMSO)273.00€JNJ-39393406
CAS:JNJ-39393406 is an α7 nicotinic acetylcholine receptor positive allosteric modulator for the study of tobacco dependence and Alzheimer's disease.Formula:C19H18F2N6O3Purity:98.36%Color and Shape:SolidMolecular weight:416.38VU0238441
CAS:VU0238441 is agonist of Muscarinic acetylcholine receptor M5 (human) with EC50 of 2.1μM.Formula:C16H9ClF3NO2Purity:100%Color and Shape:SolidMolecular weight:339.7(±)-Darifenacin
CAS:(±)-Darifenacin is the racemate of Darifenacin. Darifenacin is a selective antagonist of M3 muscarinic receptor.Formula:C28H30N2O2Color and Shape:SolidMolecular weight:426.55Pozanicline dihydrochloride
CAS:Pozanicline dihydrochloride (ABT-089 dihydrochloride) is an orally bioavailable agonist of nicotinic acetylcholine receptor (nAChR) (Ki = 16.7 nM)Formula:C11H18Cl2N2OPurity:98%Color and Shape:SolidMolecular weight:265.18Cyclodrine hydrochloride
CAS:Cyclodrine hydrochloride is a dual cholinergic muscarinic receptor (mAChR) and nicotinic receptor (nAChR) antagonist that can be used in the study ofFormula:C19H30ClNO3Purity:98.59%Color and Shape:SolidMolecular weight:355.9Tiotropium Bromide hydrate
CAS:Tiotropium Bromide hydrate is a potent, long-lasting anticholinergic bronchodilator for COPD, with high affinity for muscarinic receptors M1, M2, and M3.Formula:C19H24BrNO5S2Purity:98.44% - 99.41%Color and Shape:SolidMolecular weight:490.43TQS
CAS:TQS (4-Naphthalen-1-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide) is a positive allosteric modulator of α7 nACh receptors.Formula:C22H20N2O2SPurity:98.56%Color and Shape:SolidMolecular weight:376.47Ref: TM-T23469
2mg34.00€5mg50.00€10mg80.00€25mg156.00€50mg243.00€100mg359.00€200mg510.00€1mL*10mM (DMSO)52.00€Pipecuronium bromide
CAS:Pipecuronium bromide (RGH-1106) is an nAChR antagonist that also acts as a non-depolarising steroidal neuromuscular blocker that causes muscle relaxation.Formula:C35H62Br2N4O4Purity:100%Color and Shape:PowderMolecular weight:762.7TC-2216
CAS:TC-2216 is a partial agonist at the neural nicotinic acetylcholine receptor and is used to treat anxiety and depression.Formula:C12H17N3Purity:100.00%Color and Shape:SolidMolecular weight:203.28Sulfoxaflor
CAS:Sulfoxaflor (GF 2032) is an agonist of nAChR1 and nAChR2 subtypes and a systemic insecticide. Cost-effective and quality-assured.Formula:C10H10F3N3OSPurity:99.87%Color and Shape:SolidMolecular weight:277.27Metixene hydrochloride
CAS:Metixene hydrochloride is an anticholinergic antiparkinsonian agent.Formula:C20H24ClNSPurity:98%Color and Shape:SolidMolecular weight:345.93Methscopolamine
CAS:Methscopolamine (Hyoscine methyl bromide) (Pamine), as a natural plant alkaloid, is a muscarinic acetylcholine receptor blocker.Formula:C18H24BrNO4Purity:99.12% - ≥98%Color and Shape:SolidMolecular weight:398.29Metixene hydrochloride hydrate
CAS:Metixene HCl hydrate is a potential anticholinergic for Parkinson's with IC50 of 55 nM and Ki of 15 nM against muscarine receptors.Formula:C20H26ClNOSPurity:99.88%Color and Shape:SolidMolecular weight:363.95JHU37160
CAS:JHU37160 is a DREADD agonist with Ki of 1.9 nM for hM3Dq, 3.6 nM for hM4Di, and EC50 of 18.5 nM (hM3Dq), 0.2 nM (hM4Di) in HEK-293 cell assays.Formula:C19H20ClFN4Purity:99.87%Color and Shape:SolidMolecular weight:358.84Vesamicol hydrochloride
CAS:Vesamicol hydrochloride ((±)-AH5183 hydrochloride) is a acetylcholine transport inhibitor.Formula:C17H26ClNOPurity:98.31%Color and Shape:SolidMolecular weight:295.85Cyclopentolate Hydrochloride
CAS:Cyclopentolate Hydrochloride is a muscarinic acetylcholine receptors antagonist with Kis of 1.62, 27.5, and 2.63 nM for M1, M2, and M3 receptors, respectively.Formula:C17H26ClNO3Purity:99.91%Color and Shape:SolidMolecular weight:327.85Monepantel
CAS:Monepantel (AAD1566) is an organic anthelmintic and an antagonist of nAChRs from roundworms and esophageostomy.Formula:C20H13F6N3O2SPurity:99.76%Color and Shape:White PowderMolecular weight:473.39Ref: TM-T16126
1mg87.00€5mg250.00€10mg359.00€25mg707.00€50mg1,017.00€100mg1,454.00€1mL*10mM (DMSO)274.00€Benzethonium chloride
CAS:Benzethonium chloride (Quatrachlor) is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties.Formula:C27H42ClNO2Purity:99.91%Color and Shape:White To Off-White Solid Solid Particulate/PowderMolecular weight:448.09(Rac)-Sabcomeline HCl
CAS:Sabcomeline HCl is an M1 receptor agonist that can be used to study Alzheimer's disease.Formula:C10H16ClN3OPurity:99.03%Color and Shape:SoildMolecular weight:229.71Mivacurium dichloride
CAS:Mivacurium dichloride: non-depolarizing, quick-acting muscle relaxant for minor surgeries and tracheal intubation.Formula:C58H80Cl2N2O14Purity:99.2% - 99.48%Color and Shape:Off-White SolidMolecular weight:1100.17Ref: TM-T22371
2mg48.00€5mg69.00€10mg89.00€25mg130.00€50mg198.00€100mg303.00€200mg457.00€1mL*10mM (DMSO)96.00€(S)-(+)-Dimethindene maleate
CAS:(S)-(+)-Dimethindene maleate is an orally available, selective muscarinic M2 receptor and histamine H1 receptor antagonist that inhibits muscarinic M1 receptorsFormula:C24H28N2O4Purity:99.43%Color and Shape:SolidMolecular weight:408.49Benactyzine hydrochloride
CAS:Benactyzine hydrochloride (Neuroleptone) is a centrally acting muscarinic antagonist.Formula:C20H26ClNO3Purity:100% - 99.68%Color and Shape:SolidMolecular weight:363.88Pozanicline
CAS:Pozanicline, a selective α4β2 nAChR partial agonist (Ki=16 nM), may treat nicotine addiction by reversing cognitive deficits.Formula:C11H16N2OPurity:98%Color and Shape:SolidMolecular weight:192.26CP-810123
CAS:CP-810123 is an α7 nAChR agonist used to treat cognitive deficits associated with psychiatric or neurological disorders such as schizophrenia.Formula:C14H18N4OPurity:98.63% - 99.23%Color and Shape:SolidMolecular weight:258.32Pozanicline hydrochloride
Pozanicline hydrochloride is an oral α4β2 nAChR agonist with a 16.7 nM Ki, insignificantly binding to α7 nAChR.Formula:C11H17ClN2OPurity:99.6%Color and Shape:SolidMolecular weight:228.72Ref: TM-T16563L
1mg77.00€5mg155.00€10mg220.00€25mg338.00€50mg472.00€100mg632.00€200mg853.00€1mL*10mM (DMSO)134.00€Gallamine triethiodide
CAS:Gallamine triethiodide (Benzkurin), a synthetic inhibiting drug, is nondepolarizing.Formula:C30H60I3N3O3Purity:98.90%Color and Shape:White Amorphous Powder SolidMolecular weight:891.53Donepezil Hydrochloride
CAS:Donepezil HCl(Aricept) is a selective and effective AChE inhibitor for bAChE and hAChE (IC50: 8.12/11.6 nM).Formula:C24H29NO3·HClPurity:99.55% - 99.8%Color and Shape:White To Off-White Crystalline SolidMolecular weight:415.969-CP-Ade Mesylate
CAS:9-CP-Ade Mesylate (9 CP Ade Mesylate) is a cell-permeable, stable and non-competitive inhibitor of adenylate cyclase.Formula:C11H17N5O3SPurity:99.91%Color and Shape:SolidMolecular weight:299.35PHA 543613
CAS:PHA 543613 is a specific agonist of α7 nAChR (Ki = 8.8 nM) and can be used in studies about the cognitive deficits of Alzheimer's disease and schizophrenia.Formula:C15H17N3O2Purity:99% - 99.48%Color and Shape:SolidMolecular weight:271.31Ref: TM-T23145
1mg50.00€5mg107.00€10mg170.00€25mg378.00€50mg645.00€100mg945.00€500mg2,052.00€1mL*10mM (DMSO)105.00€Afacifenacin
CAS:Afacifenacin (SMP-986) fumarate is an M3-selective antagonist for ischemic heart disease and urinary disorders.Formula:C27H26F3N3O2Purity:99.57%Color and Shape:SolidMolecular weight:481.51(-)-OPC-51803
CAS:(-)-OPC-51803 is an antidiuretic hormone V2 receptor agonist used in the treatment of nocturia and urinary incontinence.Formula:C26H32ClN3O2Purity:100% - 100.00%Color and Shape:SoildMolecular weight:454NS9283
CAS:NS9283, a positive allosteric modulator selective for the α4β2 form, reduces ethanol consumption.Formula:C14H8N4OPurity:98.81%Color and Shape:SolidMolecular weight:248.24Ref: TM-T28199
1mg46.00€5mg96.00€10mg144.00€25mg298.00€50mg469.00€100mg687.00€500mg1,444.00€1mL*10mM (DMSO)97.00€TMPH
CAS:TMPH is an inhibitor of nAChR and inhibits nAChRs lacking α5, α6, or β3 subunits. TMPH can be used in studies about nAChR dysfunction or neurological disorders.Formula:C16H31NO2Purity:99.78%Color and Shape:SoildMolecular weight:269.42Ref: TM-T60080
2mg38.00€5mg58.00€10mg88.00€25mg140.00€50mg215.00€100mg319.00€200mg449.00€1mL*10mM (DMSO)57.00€DL-trihexyphenidyl hydrochloride
CAS:DL-trihexyphenidyl hydrochloride (Trihexyphenidyl HCl) is a muscarinic antagonist.Formula:C20H32ClNOPurity:99.63% - 99.71%Color and Shape:SolidMolecular weight:337.93(S)-UFR2709 hydrochloride
CAS:(S)-UFR2709 HCl: competitive nAChR blocker, prefers α4β2 over α7, lessens anxiety & alcohol intake in rats, studies nicotine addiction.Formula:C13H18ClNO2Purity:98.94%Color and Shape:SolidMolecular weight:255.74Ref: TM-T37094
1mg42.00€5mg88.00€10mg120.00€25mg235.00€50mg354.00€100mg550.00€500mg1,159.00€1mL*10mM (DMSO)92.00€Acetamiprid
CAS:Acetamiprid: nAChR agonist, global neonicotinoid insecticide linked to neuromuscular/reproductive issues.Formula:C10H11ClN4Purity:99.66%Color and Shape:White PowderMolecular weight:222.67LY2033298
CAS:LY2033298 enhances oximoline's effect on hamster circadian rhythms, aiding neurosystem disorders.Formula:C13H14ClN3O2SPurity:99.06%Color and Shape:SolidMolecular weight:311.79Hydroxybupropion
CAS:Hydroxybupropion (6-Hydroxybupropion) is the major active metabolite of Bupropion and an antagonist of nACh receptor. Hydroxybupropion inhibits norepinephrine uptake (IC50 = 1.7 μM).Formula:C13H18ClNO2Purity:98.61%Color and Shape:Off-White SolidMolecular weight:255.74Ref: TM-T11588
1mg115.00€2mg170.00€5mg276.00€10mg430.00€25mg690.00€50mg917.00€100mg1,272.00€1ml*10 (DMSO)276.00€McN-A 343
CAS:McN-A 343: Selective M1 muscarinic agonist; reduces inflammation in colitis models.Formula:C14H18Cl2N2O2Purity:99.82%Color and Shape:SolidMolecular weight:317.21
