
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase
- Cysteine Protease
- DPP-4
- Glutaminase
- HCV Protease
- HIV Protease
- p97
- PAI-1
- Protease-activated Receptor
- Protease Inhibitors
- Proteasome
- Serine Protease
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Products of "Proteases/Proteasome"
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JTE-607
CAS:JTE-607 is a cytokine production inhibitor. JTE-607 induces apoptosis accompanied by an increase in p21waf1/cip1 in acute myelogenous leukemia cells.Formula:C25H33Cl4N3O5Purity:97.88%Color and Shape:SolidMolecular weight:597.36Ref: TM-T27695
1mg44.00€2mg57.00€5mg87.00€10mg159.00€25mg328.00€50mg558.00€100mg797.00€1mL*10mM (DMSO)115.00€(-)-Gallocatechin Gallate
CAS:Formula:C22H18O11Purity:>95.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:458.38Torilin
CAS:Torilin is an inhibitor of testosterone 5 alpha-reductase, it (IC50 = 31.7 +/- 4.23 microM) shows a stronger inhibition of 5 alpha-reductase than alpha-Formula:C22H32O5Purity:98%Color and Shape:SolidMolecular weight:376.49BT1718
CAS:BT1718 is a bicyclic peptide conjugate that targets MT1-MMP, a protease overexpressed in various advanced solid tumors such as triple-negative breast cancer (Formula:C159H218ClN31O47S5Purity:98%Color and Shape:SolidMolecular weight:3511.39MMP-2/MMP-9 Inhibitor I
CAS:MMP-2/MMP-9-IN-1: oral IV collagenase inhibitor; IC50: 0.24 μM (MMP-9), 0.31 μM (MMP-2); targets cancer.Formula:C21H19NO4SPurity:99.74%Color and Shape:SolidMolecular weight:381.44Ref: TM-T21512
1mg59.00€5mg126.00€10mg187.00€25mg376.00€50mg622.00€100mg938.00€500mg1,882.00€1mL*10mM (DMSO)169.00€Sofosbuvir
CAS:Sofosbuvir (GS 7977) is a uridine monophosphate analog inhibitor of hepatitis C virus (HCV) polymerase NS5B that is used as an antiviral agent in the treatmentFormula:C22H29FN3O9PPurity:99.77% - 99.82%Color and Shape:SolidMolecular weight:529.45HCV-IN-29
CAS:HCV-IN-29 is a hepatitis C virus (HCV) inhibitor.Formula:C26H32Cl4N6Purity:99.66%Color and Shape:SolidMolecular weight:570.38Saxagliptin hydrate
CAS:Saxagliptin hydrate (Onglyza hydrate) is a selective and reversible DPP4 inhibitor (IC50: 26 nM; Ki: 1.3 nM).Formula:C18H25N3O2·H2OPurity:99.52%Color and Shape:SolidMolecular weight:333.43Daclatasvir
CAS:Daclatasvir (EBP 883/BMS-790052) is a potent HCV NS5A inhibitor with EC50 9-50 pM across various genotypes. Phase 3.Formula:C40H50N8O6Purity:99.81%Color and Shape:SolidMolecular weight:738.88MJN68390
CAS:MJN68390 has an apparent IC50 value of 15 μM against CASP8 and shows no activity against CASP10.Formula:C24H28ClN3O3Purity:99.06%Color and Shape:SolidMolecular weight:441.95Hck-IN-1
CAS:Hck-IN-1 selectively inhibits Nef:Hck, IC50: 2.8 μM; >20 μM for Hck alone. Potent HIV-1 Nef antagonist, IC50: 100-300 nM for HIV-1 replication.Formula:C16H11ClN6O3SPurity:99.07%Color and Shape:SolidMolecular weight:402.81Ref: TM-T11538
1mg97.00€5mg216.00€10mg344.00€25mg567.00€50mg825.00€100mg1,121.00€200mg1,510.00€1mL*10mM (DMSO)240.00€AMD 3465 hexahydrobromide
CAS:AMD 3465 hexahydrobromide (GENZ-644494 (hexahydrobromide)) is a CXCR4 receptor antagonist with potential anticancer and anti-HIV activity.Formula:C24H44Br6N6Purity:99.39%Color and Shape:SolidMolecular weight:896.07Hirudin
CAS:Hirudin is an anticoagulant extracted from leeches, a thrombin inhibitor, used in diabetic nephropathy research.Formula:C66H93N13O25Purity:99.75%Color and Shape:SolidMolecular weight:1468.52Ref: TM-T126366
1mg180.00€5mg449.00€10mg655.00€25mg1,026.00€50mg1,388.00€100mg1,872.00€200mg2,527.00€Fosdevirine
CAS:Fosdevirine (GSK2248761), a non-nucleoside reverse transcriptase (NNRTI) inhibitor with anti-HIV activity, is used in the study of neurological related diseasesFormula:C20H17ClN3O3PPurity:99.94%Color and Shape:SolidMolecular weight:413.79Dasabuvir
CAS:Dasabuvir (ABT-333) blocks HCV replication by inhibiting the essential NS5B RNA polymerase.Formula:C26H27N3O5SPurity:99.54% - 99.62%Color and Shape:SolidMolecular weight:493.57MMP-9-IN-7
CAS:N-[2-[(5-Cl-2-methoxyphenyl)amino]-4'-methyl[4,5'-bithiazol]-2'-yl]acetamide inhibits pro-MMP activation, treats MMP9/MMP13 syndromes.Formula:C16H15ClN4O2S2Purity:97.35%Color and Shape:SolidMolecular weight:394.9Ref: TM-T72069
1mg64.00€5mg131.00€10mg188.00€25mg325.00€50mg487.00€100mg708.00€500mg1,483.00€1mL*10mM (DMSO)131.00€Lusutrombopag
CAS:Lusutrombopag (Mulpleta) is an orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist for chronic liver disease (CLD) patients withFormula:C29H32Cl2N2O5SPurity:99.96%Color and Shape:SolidMolecular weight:591.55Ref: TM-TQ0223
1mg74.00€2mg96.00€5mg165.00€10mg255.00€25mg492.00€50mg715.00€100mg1,008.00€1mL*10mM (DMSO)208.00€Aloin(mixture of A&B)
CAS:ALOIN Inhibits Interleukin (IL)-1β-Stimulated IL-8 Production in KB Cells.Formula:C21H22O9Purity:99.36%Color and Shape:SolidMolecular weight:418.39Histatin 5 (TFA)(115966-68-2,free)
Histatin 5 (TFA)(115966-68-2,free) (Histatin 5 (TFA)) inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μMFormula:C135H196F3N51O35Purity:98%Color and Shape:SolidMolecular weight:3150.32Acetohydroxamic acid
CAS:Acetohydroxamic acid (N-Hydroxyacetamide) is an antagonist of the bacterial enzyme urease.Formula:C2H5NO2Purity:99.82% - 99.91%Color and Shape:SolidMolecular weight:75.07