Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase
- Cysteine Protease
- DPP-4
- Glutaminase
- HCV Protease
- HIV Protease
- p97
- PAI-1
- Protease-activated Receptor
- Protease Inhibitors
- Proteasome
- Serine Protease
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Products of "Proteases/Proteasome"
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KZR-504
CAS:KZR-504 is a selective inhibitor of immunoproteasome low molecular mass polypeptide 2 (LMP2) (IC50s: 51 nM, 4.274 μM for LMP2 and LMP7, respectively).Formula:C21H23N3O6Color and Shape:SolidMolecular weight:413.42Oxyresveratrol
CAS:1.Formula:C14H12O4Purity:98.09% - 99.69%Color and Shape:Yellow SolidMolecular weight:244.24Picroside I
CAS:Picroside I (6'-Cinnamoylcatalpol), a hepatoprotective agent, is reported to be antimicrobial and used against hepatitis B.Formula:C24H28O11Purity:99.70%Color and Shape:SolidMolecular weight:492.47Caspase-3 activator 2
Caspase-3 Activator 2 (Compound 2f) is a caspase 3 activator with cytotoxic effects on HL-60 and K562 cells, exhibiting IC 50 values of 33.52 μM and 76.90 μM,Purity:98%Color and Shape:Odour SolidTAPI1 acetate
TAPI1 acetate (TNF-α processing inhibitor-1) is a TACE (ADAM17) inhibitor that inhibits shedding of TNF-α cytokine receptors; MMP inhibitor .Formula:C28H41N5O7Purity:98.82%Color and Shape:SolidMolecular weight:559.651,4,6-Heptatrien-3-one
CAS:Bisdemethoxycurcumin activates the AMPKα pathway;inhibits tyrosinas; targets pathways oxidative stress and apoptosis;anticancer.Formula:C19H16O4Color and Shape:SolidMolecular weight:308.332,3-Dihydrohinokiflavone
CAS:2,3-Dihydrohinokiflavone is a suppressor of matrix metalloproteinases (MMP) gene expression and shows strong activity against Leishmania with an IC50 of 1.6 μM.Formula:C30H20O10Purity:98%Color and Shape:SolidMolecular weight:540.47Ref: IN-DA0072SK
1gTo inquire5mg70.00€10mg129.00€25mg160.00€50mg209.00€100mg271.00€250mg593.00€500mgTo inquireSofosbuvir impurity G
CAS:Sofosbuvir impurity G is both a diastereomer of Sofosbuvir and an impurity of Sofosbuvir which is an inhibitor of HCV RNA replication.Formula:C22H29FN3O9PPurity:98.04%Color and Shape:SolidMolecular weight:529.45Ref: TM-T12962
1mg1,103.00€5mg2,547.00€10mg3,449.00€25mg5,120.00€50mg6,925.00€1mL*10mM (DMSO)3,202.00€TERT-IN-1
CAS:TERT-IN-1 has anti-HIV activity and can be used to study HIV infection.Formula:C16H20ClN3SPurity:99.31%Color and Shape:SoildMolecular weight:321.87ZINC09518833
CAS:ZINC09518833 is an α-ketoamide non-peptide proteasome inhibitor with an IC50 value of 12.4 μM. It can bind with both the active and inactive sites of the proteasome. ZINC09518833 shows promise for use in research related to multiple myeloma (MM).Formula:C24H25N3O5Color and Shape:SolidMolecular weight:435.47Z-FY-CHO
CAS:Pyridoxal (Pyridoxaldehyde), a component of vitamin B6, is an aldehyde obtained by oxidizing pyridoxine and is widely found in plants and animals.Formula:C26H26N2O5Color and Shape:SolidMolecular weight:446.5BMS-707035
CAS:BMS-707035 is a specific HIV-I integrase (IN) inhibitor with IC50 of 15 nM. Phase 2.Formula:C17H19FN4O5SPurity:99.78%Color and Shape:SolidMolecular weight:410.42LU-002i
CAS:LU-002i is a selective inhibitor targeting the human proteasome subunits β2c and β2i, demonstrating an inhibitory concentration (IC50) of 220 nM for β2i [1].Formula:C35H52N4O7Purity:98%Color and Shape:SolidMolecular weight:640.81Cys-TAT(47-57) acetate(583836-55-9 Free base)
Cys-TAT(47-57) acetate is derived from the HIV-1 transactivating protein. Cys-TAT(47-57) acetate is an arginine rich peptide that can penetrate cells.Formula:C69H128N34O16SPurity:95.11%Color and Shape:SolidMolecular weight:1722.04Elsulfavirine
CAS:Elsulfavirine (VM-1500) is an HIV-1 infection reverse transcriptase inhibitor. It is a new anti-HIV drug.Formula:C24H17BrCl2FN3O5SPurity:99.66%Color and Shape:SolidMolecular weight:629.28Ref: TM-T15210
1mg72.00€5mg156.00€10mg243.00€25mg487.00€50mg730.00€100mg1,026.00€1mL*10mM (DMSO)210.00€Balicatib
CAS:Balicatib (AAE581) is a potent and selective inhibitor of cathepsin K, used in trials studying the treatment of osteoporosis.Formula:C23H33N5O2Purity:97.78% - 98.09%Color and Shape:White To Off-White Solid PowderMolecular weight:411.54Ref: TM-T1850
2mg42.00€5mg62.00€10mg99.00€25mg224.00€50mg378.00€100mg605.00€200mg848.00€1mL*10mM (DMSO)67.00€Ixazomib
CAS:Ixazomib (MLN2238) is a boron-based peptide proteasome inhibitor targeting β5 site (IC50: 3.4 nM), also affecting β1 and β2 sites.Formula:C14H19BCl2N2O4Purity:98% - 98.92%Color and Shape:SolidMolecular weight:361.03Ref: TM-T2122
1mg48.00€5mg95.00€10mg127.00€25mg259.00€50mg416.00€100mg652.00€200mg922.00€1mL*10mM (DMSO)97.00€(2RS)-FPMPA
CAS:(2RS)-FPMPA(FPMPA) has antiviral activity with an IC50 value of 1.85 μM measured in human MT12 cells infected with SHIV (DH4R).Formula:C9H13FN5O4PPurity:100% - 99.90%Color and Shape:SolidMolecular weight:305.2
