
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase
- Cysteine Protease
- DPP-4
- Glutaminase
- HCV Protease
- HIV Protease
- p97
- PAI-1
- Protease-activated Receptor
- Protease Inhibitors
- Proteasome
- Serine Protease
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Products of "Proteases/Proteasome"
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PR 39 (porcine) acetate
PR 39 (porcine) acetate is a noncompetitive, reversible and allosteric proteasome inhibitor.Purity:98%Color and Shape:LiquidMolecular weight:N/ADolutegravir sodium
CAS:Dolutegravir sodium (GSK-1349572A) salt(DTG; GSK1349572) is an HIV integrase inhibitor(IC50: 2.7 nM), modest activity against raltegravir-resistant signatureFormula:C20H18F2N3NaO5Purity:98% - 99.74%Color and Shape:SolidMolecular weight:441.36EDTA, Disodium Salt, Dihydrate
CAS:EDTA disodium dihydrate chelates metals, inhibits proteases, and aids in protein purification; doesn't affect cellulase.Formula:C10H18N2Na2O10Purity:99.97%Color and Shape:SolidMolecular weight:372.24Beclabuvir
CAS:Beclabuvir blocks HCV NS5B polymerase at thumb site 1, effective on genotypes 1, 3, 4, 5 with IC50 <28 nM.Formula:C36H45N5O5SPurity:99.87% - 99.93%Color and Shape:SolidMolecular weight:659.84Sulochrin
CAS:Sulochrin shows antifungal and antibacterial activities, it can inhibit hepatitis C virus (HCV) infection in a dose-dependent manner without any apparentFormula:C17H16O7Purity:98%Color and Shape:SolidMolecular weight:332.3ISOGINKGETIN
CAS:ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion.Formula:C32H22O10Purity:98% - 99.72%Color and Shape:SolidMolecular weight:566.51Davelizomib
CAS:Davelizomib is a proteasome inhibitor that exhibits antineoplastic activity [1].Formula:C21H26BF2N3O7Purity:98%Color and Shape:SolidMolecular weight:481.25Notoginsenoside T5
CAS:TPNS from San-Chi root (Araliaceae) treats atherosclerosis by lowering lipids and modifying vascular CD40/MMP-9, suggesting clinical use.Formula:C41H68O12Purity:98%Color and Shape:SolidMolecular weight:752.983Viscumneoside III
CAS:Viscumneoside III, a dihydroflavone O-glycoside, is a potent Tyrosinase inhibitor with an IC50 of 0.5 mM. Viscumneoside III has anti-angina pectoris.Formula:C27H32O15Purity:98%Color and Shape:SolidMolecular weight:596.53Aloin
CAS:Aloin (Aloin-A)(mixture of A&B), a natural anthracycline from Aloe vera, is a tyrosinase inhibitor.Formula:C21H22O9Purity:98.28%Color and Shape:Yellow PowderMolecular weight:418.39Mizoribine
CAS:Mizoribine (NSC-289637) belongs to the family of 1-Ribosyl-imidazolecarboxamides. Mizoribine has been investigated for the treatment of Rheumatoid Arthritis.Formula:C9H13N3O6Purity:98.38% - 99.95%Color and Shape:White To Off-White Crystalline PowderMolecular weight:259.22Isatoribine
CAS:Isatoribine(ANA245) free base is a potent TLR7 receptor agonist with anti-hepatitis C virus infection activity for the study of HCV infection.Formula:C10H12N4O6SPurity:100% - 99.73%Color and Shape:SolidMolecular weight:316.29CIL62
CAS:CIL62 is a caspase-3/7-independent inducer of cell death. The mechanism of action of CIL62 is Necrostatin-1 dependent cell death [1].Formula:C23H26O5Purity:97.07%Color and Shape:SolidMolecular weight:382.45Ref: TM-T8468
1mg52.00€5mg116.00€10mg170.00€25mg335.00€50mg562.00€100mg758.00€200mg1,017.00€1mL*10mM (DMSO)128.00€HIV-1 Inhibitor 18A
CAS:HIV-1 Inhibitor 18A (HIV-1 Inhibitor-18A) specifically inhibits the entry of multiple HIV-1 isolates.Formula:C14H11N5O2SPurity:91.64%Color and Shape:SolidMolecular weight:313.33Ref: TM-T24141
1mg115.00€5mg227.00€10mg313.00€25mg535.00€50mg752.00€100mg1,064.00€1mL*10mM (DMSO)217.00€Sirpiglenastat
CAS:Sirpiglenastat (DRP-104) is a glutamine antagonist, a prodrug of DON, with antitumor activity that acts by suppressing the adaptive immune system.Formula:C22H27N5O5Purity:98.01% - 98.37%Color and Shape:SolidMolecular weight:441.48Atazanavir Sulfate
CAS:Formula:C38H52N6O7·H2SO4Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:802.94Melagatran
CAS:Melagatran is an orally available, direct synthetic thrombin inhibitor that does not require endogenous cofactors other than thrombin.Cost-effective and quality-assured.Formula:C22H31N5O4Purity:100% - 98.37%Color and Shape:SolidMolecular weight:429.51Ref: TM-T11994
1mg513.00€5mg1,198.00€10mg1,549.00€25mg2,337.00€50mg3,125.00€100mg4,246.00€1mL*10mM (DMSO)1,130.00€BMS-561392 Formic acid
BMS-561392 Formic acid is a selective inhibitor of TACE and reduces TNFalpha levels.Formula:C28H34N4O6Purity:97.25%Color and Shape:SoildMolecular weight:522.59Ref: TM-T30531L
1mg185.00€5mg424.00€10mg627.00€25mg938.00€50mg1,311.00€100mg1,795.00€500mg3,600.00€1mL*10mM (DMSO)520.00€Pseudane IX
CAS:Pseudane IX (2-nonyl-1H-quinolin-4-one) reduces infection of Huh 7.5 cells by hepatitis C virus (HCV) with an IC50 of 1.4 μg/ml.Formula:C18H25NOPurity:99.71%Color and Shape:SolidMolecular weight:271.4TG2-IN-3h
CAS:TG2-IN-3h is a highly selective, potent, cell-permeable fluorescent irreversible tissue transglutaminase (tg2) inhibitorFormula:C21H26N4O4SPurity:99.34% - 99.76%Color and Shape:SolidMolecular weight:430.52