
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase
- Cysteine Protease
- DPP-4
- Glutaminase
- HCV Protease
- HIV Protease
- p97
- PAI-1
- Protease-activated Receptor
- Protease Inhibitors
- Proteasome
- Serine Protease
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Products of "Proteases/Proteasome"
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MEGA-9
CAS:MEGA-9 (Nonanoyl-N-Methylglucamide) solubilizes membrane protein and can be used as a nonionic detergent.Formula:C16H33NO6Purity:99.59%Color and Shape:SolidMolecular weight:335.44Emtricitabine S-oxide
CAS:Emtricitabine treats HIV; its degradation byproduct is Emtricitabine S-oxide.Formula:C8H10FN3O4SPurity:98%Color and Shape:SolidMolecular weight:263.25PSI
CAS:PSI is a proteasome inhibitor.Formula:C32H50N4O8Purity:97% - 98.33%Color and Shape:SolidMolecular weight:618.76Methylchloroisothiazolinone/Methylisothiazolinone Mixture
CAS:Methylchloroisothiazolinone/Methylisothiazolinone Mixture (Kathon 886MW),a preservative, activates MMPs in human bronchial epithelial cells.Formula:C8H9ClN2O2S2Color and Shape:SolidMolecular weight:264.75Sovaprevir
CAS:Sovaprevir is a non-structural 3 (NS3) protease inhibitor with antiviral activity for the treatment of HCV infection.Formula:C43H53N5O8SPurity:99.10%Color and Shape:SolidMolecular weight:799.97Ref: TM-T28830
1mg266.00€5mg655.00€10mg934.00€25mg1,388.00€50mg1,872.00€100mg2,517.00€1mL*10mM (DMSO)1,035.00€TS-021
CAS:TS-021 is a selective dipeptidyl peptidase 4 (DPP-4) inhibitor with antidiabetic activity for the study of type 2 diabetes.Formula:C17H24FN3O5SPurity:100% - 100%Color and Shape:SolidMolecular weight:401.45RJF02215
CAS:RJF02215, an MMP-9 inhibitor, exhibits growth inhibitory activity against the ovarian cancer cell line SKOV3. It is utilized in tumor research.Formula:C17H12ClN3OS3Color and Shape:SolidMolecular weight:405.95Salicylanilide
CAS:Salicylanilide (2-Hydroxybenzanilide)s are a group of compounds with antiviral potency, antibacterial and antifungal activities.Formula:C13H11NO2Purity:99.55%Color and Shape:White To Off-White Crystalline PowderMolecular weight:213.23hTYR/AbTYR-IN-1
CAS:hTYR/AbTYR-IN-1 is a dual hTYR/AbTYR inhibitor with inhibitory effects on hTYR and AbTYR, with IC50s of 5.4 μM and 3.52 μM, respectively.Formula:C18H20N2O3Purity:99.59%Color and Shape:SoildMolecular weight:312.36Heparin
CAS:Heparin (Adomiparin) is a mucopolysaccharide sulfate that has shown partial anti-inflammatory activity in in vivo studies.Formula:C26H42N2O37S5Purity:98%Color and Shape:White Or Pale-Colored Amorphous Powder SolidMolecular weight:1134.9Oxindole
CAS:Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.Oxindole structure has been used in receptor tyrosine kinases (RTKs) inhibitors such as SU4984 and intedanib, the RTK family represents an important therapeutic target for anti-cancer drug development.Formula:C8H7NOPurity:99.34%Color and Shape:Off-White Crystalline PowderMolecular weight:133.15TCH-165
CAS:TCH-165 boosts 20S proteasome levels, enhancing IDP breakdown.Formula:C39H37N3O3Purity:98.2% - 98.75%Color and Shape:SolidMolecular weight:595.73Ref: TM-T17011
1mg74.00€5mg160.00€10mg250.00€25mg455.00€50mg682.00€100mg938.00€1mL*10mM (DMSO)265.00€KW-2450 Formate
KW-2450 Formate is an IGF-1R/IR tyrosine kinase inhibitor with antitumor effects that acts through inhibition of Aurora A and B kinases.KW-2450 Formate inhibits the growth of TNBC xenografts and induces tetraploid accumulation.Formula:C29H31N5O5SPurity:99.34%Color and Shape:SolidMolecular weight:561.65Thiamine disulfide
CAS:Thiamine disulfide (Algoneurina) , also known as thiamin or vitamin B1, is a vitamin found in food and manufactured as a dietary supplement and medication.Formula:C24H34N8O4S2Purity:99.18%Color and Shape:CoaMolecular weight:562.71Chlorcyclizine
CAS:CHLORCYCLIZINE is a histamine H1 antagonist and a potent hepatitis C virus (HCV) entry inhibitor.Formula:C18H21ClN2Purity:98% - 98.75%Color and Shape:SolidMolecular weight:300.83UK 356618
CAS:UK 356618 is a potent and selective inhibitor of matrix metalloprotease-3 (IC50: 5.9 nM).Formula:C34H43N3O4Purity:98%Color and Shape:SolidMolecular weight:557.72Cabotegravir
CAS:Cabotegravir (S/GSK1265744) (GSK744, GSK1265744) is a long-acting HIV integrase inhibitor and inhibits the HIV-1 integrase catalyzed strand transfer reaction (Formula:C19H17F2N3O5Purity:98.55% - 99.92%Color and Shape:SolidMolecular weight:405.35Tyrosinase-IN-35
CAS:Tyrosinase-IN-35 (compound 6g), exhibiting a IC 50 value of 2.09 μM, serves as a more effective inhibitor of human tyrosinase compared to Kojic Acid (IC 50: 16.38 μM). At concentrations of 4 μM and 8 μM, this compound effectively lowers melanin levels in melanoma B16F10 cells in vitro.Formula:C17H15N5OSColor and Shape:SolidMolecular weight:337.40DRB
CAS:DRB is a nucleoside analog that inhibits several carboxyl-terminal domain (CTD) kinases including casein kinase II (IC50 range of 4-10 μM)Formula:C12H12Cl2N2O4Purity:99.46%Color and Shape:White To Off-White Crystalline SolidMolecular weight:319.14Collagenase Type II
Collagenase Type II, an endopeptidic MMP-8, preferentially degrades type I collagen tissues requiring high digestive efficiency pancreas and liver.Color and Shape:Odour Solid