
Proteases/Proteasome
Protease and proteasome inhibitors are compounds that block the activity of proteases and the proteasome, which are involved in protein degradation and turnover. These inhibitors are vital for studying the regulation of protein homeostasis, cell cycle control, and apoptosis. Protease and proteasome inhibitors are also used in the treatment of diseases such as cancer, where abnormal protein degradation plays a role in disease progression. By inhibiting proteases or the proteasome, these compounds can induce cell death in cancer cells and are critical tools in both basic research and therapeutic development. At CymitQuimica, we provide a wide range of high-quality protease and proteasome inhibitors to support your research in biochemistry, cell biology, and drug development.
Subcategories of "Proteases/Proteasome"
- Acetyl-CoA Carboxylase
- Cysteine Protease
- DPP-4
- Glutaminase
- HCV Protease
- HIV Protease
- p97
- PAI-1
- Protease-activated Receptor
- Protease Inhibitors
- Proteasome
- Serine Protease
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Products of "Proteases/Proteasome"
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Ac-VRPR-AMC
CAS:Ac-VRPR-AMC is a fluorogenic substrate for metacaspase activity assays, facilitating the detection and measurement of metacaspase activity [1].Formula:C34H51N11O7Purity:98%Color and Shape:SolidMolecular weight:725.842-PMPA
CAS:2-PMPA (2-(Phosphonomethyl)pentanedioic acid) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) (IC50=300 pM).Formula:C6H11O7PPurity:98% - 99.50%Color and Shape:SolidMolecular weight:226.12Tyrosinase-IN-32
Tyrosinase-IN-32 (compound 11), a hydroxamate-based alkaloid extracted from black pepper (Piper nigrum L.), functions as an inhibitor of mushroom tyrosinase. In addition to its inhibitory properties, it exhibits antioxidant activity.Formula:C15H19NO3Color and Shape:SolidMolecular weight:261.32ABT530
CAS:ABT530 (Pibrentasvir) is an HCV NS5A inhibitor with EC50s ranging from 1.4-5.0 pM against HCV replicons containing NS5A from genotypes 1-6.Formula:C57H65F5N10O8Purity:99.15% - 99.93%Color and Shape:SolidMolecular weight:1113.18MMP-3 Inhibitor
CAS:MMP-3 Inhibitor is a peptide matrix metalloproteinase-3 (MMP-3) inhibitor with a Ki value of 95 nM.MMP-3 inhibitor has anticancer and antitumor activity.Formula:C27H46N10O9SPurity:98.87%Color and Shape:SolidMolecular weight:686.78Ref: TM-T37048
1mg81.00€5mg208.00€10mg309.00€25mg525.00€50mg757.00€100mg1,035.00€500mg2,110.00€1mL*10mM (DMSO)221.00€Isoangustone A
CAS:Isoangustone A has antitumor activity, it can induce G1 cycle arrest in DU145 human prostate and 4T1 murine mammary cancer cells, it inhibits cell proliferationFormula:C25H26O6Purity:98%Color and Shape:SolidMolecular weight:422.47MMP13-IN-3
CAS:MMP13-IN-3 is an oral, selective MMP-13 inhibitor with IC50 of 1 nM, >1000x selective, for osteoarthritis treatment.Formula:C24H22N4O5Purity:99.05%Color and Shape:SolidMolecular weight:446.46Ref: TM-T16124
1mg87.00€5mg216.00€10mg354.00€25mg620.00€50mg847.00€100mg1,169.00€1mL*10mM (DMSO)240.00€N-α-Tosyl-L-lysine chloromethyl ketone hydrochloride
CAS:N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride inhibits trypsin-like proteases and IFN-γ activities.Formula:C14H22Cl2N2O3SPurity:97.44%Color and Shape:PowderMolecular weight:369.31TNF Protease Inhibitor 2
CAS:TAPI-2 is a broad-spectrum inhibitor of MMP (IC50: 20 μM), tumour necrosis factorα-converting enzyme (TACE) and a disintegrin and metalloproteinase (ADAM).Formula:C19H37N5O5Purity:98%Color and Shape:SolidMolecular weight:415.53MG-132
CAS:Formula:C26H41N3O5Purity:>95.0%(qNMR)Color and Shape:White to Light yellow powder to crystalMolecular weight:475.63Z-Leu-Leu-Tyr-COCHO
CAS:Z-Leu-Leu-Tyr-COCHO is a potent inhibitor of chymotrypsin-like activity, exhibiting a Ki value of 3.0 nM [1].Formula:C30H39N3O7Purity:98%Color and Shape:SolidMolecular weight:553.65Emivirine
CAS:Emivirine (MKC-442) is a potent and selective nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1.Formula:C17H22N2O3Purity:99.68%Color and Shape:SolidMolecular weight:302.37Benzylsulfonyl Fluoride [for Biochemical Research]
CAS:Formula:C7H7FO2SPurity:>98.0%(GC)Color and Shape:White to Almost white powder to crystalMolecular weight:174.19BI 224436
CAS:BI 224436 is an inhibitor of HIV-1 noncatalytic site integrase. With EC50 values of less than 15 nM against different HIV-1 laboratory strains.Formula:C27H26N2O4Color and Shape:SolidMolecular weight:442.51HIV-1 protease-IN-9
CAS:HIV-1 protease-IN-9 (compound 5b), a potent HIV-1 protease inhibitor, exhibits strong antiviral efficacy with a dissociation constant (K_i) of 0.028 nM and aFormula:C37H41N7O4SPurity:98%Color and Shape:SolidMolecular weight:679.83CDK9-IN-30
CAS:CDK9-IN-30 is one of the Tat peptide derivatives and inhibits HIV-1 long terminal repeat-activated transcription.Formula:C16H20FNO3Purity:99.76%Color and Shape:SolidMolecular weight:293.33Ref: TM-T9632
1mg56.00€5mg119.00€10mg187.00€25mg316.00€50mg472.00€100mg658.00€500mg1,378.00€1mL*10mM (DMSO)114.00€GLPG2451
CAS:GLPG2451 potentiates F508del CFTR at low temp (EC50: 11.1 nM), aiding cystic fibrosis treatment.Formula:C16H16F3N3O5SColor and Shape:SolidMolecular weight:419.38Trisodium Hydrogen Ethylenediaminetetraacetate Hydrate [for Biochemical Research]
CAS:Formula:C10H13N2Na3O8·xH2OPurity:>98.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:358.19 (as Anhydrous)Benzoic acid, 4-[(aminoiminomethyl)amino]-, 6-(aminoiminomethyl)-2-naphthalenyl ester, dimethanesulfonate
CAS:Formula:C21H25N5O8S2Purity:98%Color and Shape:SolidMolecular weight:539.5819MMP-2 Inhibitor-4
MMP-2Inhibitor-4 (Compound 5g) is an MMP-2 inhibitor with an IC50 of 152.62 nM. It effectively reduces MMP-2 levels in K562 cell lines by stably binding to the active site of MMP-2 and exhibits strong anti-angiogenic effects in ACHN cell lines. MMP-2Inhibitor-4 shows potential for research in chronic myelogenous leukemia (CML).Formula:C19H23N3O5SMolecular weight:405.468