Wnt/beta-catenin
Wnt/beta-catenin inhibitors are compounds that target and inhibit the Wnt/beta-catenin signaling pathway, which is crucial for the regulation of embryonic development, cell proliferation, and stem cell maintenance. Dysregulation of this pathway is linked to various cancers and degenerative diseases. Inhibitors of Wnt/beta-catenin signaling are valuable in research focused on understanding the role of this pathway in disease and developing targeted therapies. At CymitQuimica, we offer Wnt/beta-catenin inhibitors to support your research in stem cell biology, developmental biology, and cancer research.
Products of "Wnt/beta-catenin"
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WIC1
CAS:2H-1-Benzopyran-3-carboxamide, N-[4-(4-ethyl-1-piperazinyl)phenyl]-2-oxo- is a compound that is potential for the treatment of tumours.Formula:C22H23N3O3Purity:99.57%Color and Shape:SoildMolecular weight:377.44F7H
CAS:F7H is an FZD7 antagonist, a potent ligand for the FZD7 transmembrane domain (TMD), with potential antitumor and bacteriostatic activities.Formula:C24H18FN3O2S2Purity:99.85%Color and Shape:SoildMolecular weight:463.55NRX-103094
CAS:NRX-103094 boosts β-catenin binding to SCFβ-TrCP ligase with EC50 62 nM and Kd 0.6 nM.Formula:C20H11Cl2F3N2O4SPurity:99.50%Color and Shape:SolidMolecular weight:503.28Gossypolone
CAS:Gossypolone is is a proposed major metabolite of gossypol. Gossypolone reduces Notch/Wnt signaling and induces apoptosis.Formula:C30H26O10Purity:96.66%Color and Shape:SolidMolecular weight:546.52TNKS-2-IN-2
CAS:TNKS-2-IN-2 is a TNKS2 selective inhibitor (IC50: 22 nM) with potential anti-tumour activity for the study of colon cancer lung cancer and breast cancer.Formula:C26H23N3O6Purity:99.45%Color and Shape:SoildMolecular weight:473.48KYA1797K
CAS:KYA1797K is a highly potent and selective inhibitor. Wnt/β-catenin IC50 is 0.75 μM through TOPflash assay.Formula:C17H11N2O6S2·KPurity:97.57% - 99.33%Color and Shape:SolidMolecular weight:442.51N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide
CAS:Macamide Impurity 14 promotes bone growth by activating Wnt/β-catenin, aiding osteoporosis study.Formula:C26H39NO2Purity:98.66%Color and Shape:SolidMolecular weight:397.59TNIK-IN-3
CAS:TNIK-IN-3 is a highly potent and orally active inhibitor of Traf2- and Nck-interacting protein kinase (TNIK).Formula:C23H18FN3O2Purity:99.56%Color and Shape:SolidMolecular weight:387.41Ref: TM-T9556
1mg106.00€5mg259.00€10mg406.00€25mg652.00€50mg938.00€100mg1,454.00€1mL*10mM (DMSO)284.00€ZW4864 free base
CAS:ZW4864 (free base) is an orally active and selective β catenin/B-Cell lymphoma 9 protein protein interaction ( β catenin/BCL9 PPI ) inhibitor.Formula:C33H42N6O3Purity:99.54%Color and Shape:SolidMolecular weight:570.72Ref: TM-T9642
1mg160.00€5mg393.00€10mg587.00€25mg935.00€50mg1,264.00€100mg1,700.00€500mg3,410.00€1mL*10mM (DMSO)432.00€iCRT 14
CAS:iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT)(IC50= 40.3 nM in assays of Wnt pathway activity).Formula:C21H17N3O2SPurity:98.85% - 99.8%Color and Shape:SolidMolecular weight:375.44IQ 1
CAS:IQ 1 has multiple roles, such as maintaining the multifunctionality of mouse ESCs, decreasing Wnt-stimulated phosphorylation, blocking PP2A/Nkd interactions.Formula:C21H22N4O2Purity:98.57% - ≥95%Color and Shape:SolidMolecular weight:362.42Ref: TM-T3635
5mg51.00€10mg78.00€25mg140.00€50mg195.00€100mg350.00€200mg500.00€500mg810.00€1mL*10mM (DMSO)57.00€CDK8-IN-11
CAS:CDK8-IN-11 is a CDK8 inhibitor that demonstrates anti-proliferative activity against colon cancer cell lines and inhibits the activation of WNT/β-catenin.Formula:C19H15F3N4O2Purity:99.74%Color and Shape:SolidMolecular weight:388.34Ref: TM-T61742
1mg59.00€5mg127.00€10mg205.00€25mg454.00€50mg748.00€100mg1,054.00€200mg1,415.00€1mL*10mM (DMSO)139.00€YW2036
CAS:YW2036 is an inhibitor of Wnt signaling pathway.Formula:C20H16N4OPurity:100%Color and Shape:SoildMolecular weight:328.37LF3
CAS:LF3 is a specific inhibitor of canonical Wnt signaling by disrupting the interaction between β-catenin and TCF4 (IC50 < 2 μM)Formula:C20H24N4O2S2Purity:99.63%Color and Shape:SolidMolecular weight:416.56SRI 37892
CAS:SRI 37892 is a Fzd7 inhibitor with potent activities against Wnt/β-catenin signaling and cancer cell viability.Formula:C26H19N5O2SPurity:98.92%Color and Shape:SolidMolecular weight:465.53Ref: TM-T9662
1mg378.00€5mg922.00€10mg1,225.00€25mg1,853.00€50mg2,490.00€100mg3,353.00€1mL*10mM (DMSO)1,074.00€FzM1.8
CAS:FzM1.8: allosteric FZD4 agonist, pEC50=6.4; boosts TCF/LEF, activates WNT/β-catenin with no WNT needed.Formula:C18H14N2O4Purity:100%Color and Shape:SolidMolecular weight:322.31Ref: TM-T15363
2mg42.00€5mg60.00€10mg96.00€25mg177.00€50mg283.00€100mg454.00€200mg653.00€1mL*10mM (DMSO)95.00€Neurodazine
CAS:Neurodazine is a neural inducer that promotes the differentiation of pluripotent cells into neuronal cells.Formula:C27H21ClN2O3Purity:98.01%Color and Shape:SolidMolecular weight:456.92Carboxylesterase-IN-3
CAS:Carboxylesterase-IN-3 is a potent inhibitor of Carboxylesterase Notum (IC50 ≤ 10 nM).Carboxylesterase-IN-3 has the potential to study cancer diseases.Formula:C11H6Cl2N4OSPurity:97.49% - 97.89%Color and Shape:SolidMolecular weight:313.16Nefopam hydrochloride
CAS:Nefopam hydrochloride (Nefopam HCl) is the hydrochloride salt form of nefopam, a centrally-acting, non-opioid benzoxazocine with analgesic activity.Formula:C17H20ClNOPurity:99.32% - 99.85%Color and Shape:SolidMolecular weight:289.8TINK-IN-1
CAS:TINK-IN-1 is a selective and potent TNIK inhibitor (IC50: 8 nM).TINK-IN-1 inhibits colorectal cancer cell viability and can be used to study mental retardation.Formula:C24H24N4O3Purity:99.4%Color and Shape:SoildMolecular weight:416.47Ref: TM-T77660
1mg42.00€2mg52.00€5mg87.00€10mg127.00€25mg250.00€50mg373.00€100mg547.00€500mg1,159.00€
