Wnt/beta-catenin
Wnt/beta-catenin inhibitors are compounds that target and inhibit the Wnt/beta-catenin signaling pathway, which is crucial for the regulation of embryonic development, cell proliferation, and stem cell maintenance. Dysregulation of this pathway is linked to various cancers and degenerative diseases. Inhibitors of Wnt/beta-catenin signaling are valuable in research focused on understanding the role of this pathway in disease and developing targeted therapies. At CymitQuimica, we offer Wnt/beta-catenin inhibitors to support your research in stem cell biology, developmental biology, and cancer research.
Products of "Wnt/beta-catenin"
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Pyrvinium pamoate
CAS:Pyrvinium pamoate (Pyrvinium embonate) is an old anthelminthic medicine for the treatment of enterobiasis , which re-attracts attention as an anti-cancer drugFormula:C26H28N3C23H14O6Purity:100% - 98.43%Color and Shape:SolidMolecular weight:575.71β-catenin-IN-2
CAS:β-catenin-IN-2 is a potent inhibitor of β-catenin that can be used in colorectal cancer research.Formula:C15H14FN3Purity:98.78%Color and Shape:SolidMolecular weight:255.29Ref: TM-T9696
1mg96.00€5mg227.00€10mg359.00€25mg607.00€50mg868.00€100mg1,169.00€500mg2,365.00€1mL*10mM (DMSO)264.00€KY02111
CAS:KY02111 facilitates differentiation of hPSCs to cardiomyocytes by inhibiting Wnt signaling, maybe affect downstream of GSK3β and APC.Formula:C18H17ClN2O3SPurity:97.71%（96.56%） - 98.68%Color and Shape:SolidMolecular weight:376.86Tegatrabetan
CAS:Tegatrabetan (BC2059) is a small molecule inhibitor of the Wnt/beta-catenin pathway with potential antineoplastic activity.Formula:C28H36N4O6S2Purity:98.01% - 99.18%Color and Shape:SolidMolecular weight:588.74Ref: TM-T5642
1mg40.00€2mg52.00€5mg85.00€10mg124.00€25mg210.00€50mg334.00€100mg565.00€1mL*10mM (DMSO)96.00€CWP232228
CAS:CWP232228 is a selective Wnt/β-catenin pathway inhibitor targeting β-catenin/TCF binding, halting breast/liver CSC growth and metastasis safely.Formula:C33H34N7Na2O7PPurity:96.13%Color and Shape:SolidMolecular weight:717.63Cardiogenol C
CAS:Cardiogenol C is a cardiomyogenesis inducer in embryonic stem cells.Formula:C13H16N4O2Purity:98.46%Color and Shape:SolidMolecular weight:260.29EMT inhibitor-1
CAS:EMT inhibitor-1 is an inhibitor of Hippo, Wnt signaling and TGF- macrophages (TGF-) with antitumor activity.Formula:C12H12Cl2N2O2SPurity:99%Color and Shape:SolidMolecular weight:319.21Ref: TM-T11190
1mg111.00€5mg264.00€10mg424.00€25mg723.00€50mg1,008.00€100mg1,378.00€500mg2,737.00€1mL*10mM (DMSO)283.00€exo-IWR-1
CAS:exo-IWR-1 (exo-IWR 1) is an inactive stereoisomer of Endo-IWR-1,and is a negative control of IWR-1. IWR-1 is a tankyrase inhibitor which inhibits Wnt/β-cateninFormula:C25H19N3O3Purity:97.41%Color and Shape:SolidMolecular weight:409.44Ref: TM-T22775
5mg34.00€10mg52.00€25mg105.00€50mg173.00€100mg279.00€200mg406.00€1mL*10mM (DMSO)44.00€Vantictumab
CAS:Vantictumab (OMP-18R5) is a humanized anti-FZD1/2/5/7/8 monoclonal antibody that inhibits Wnt pathway signaling.Color and Shape:Liquidβ-catenin/CBP-IN-1
CAS:β-catenin/CBP-IN-1 is a potent and selective inhibitor of CBP/β-cateninFormula:C33H35N6O7PPurity:98%Color and Shape:SolidMolecular weight:658.64Ipafricept
CAS:Ipafricept (OMP-54F28) is a recombinant fusion protein and Wnt inhibitor that blocks Wnt signaling.Color and Shape:LiquidSKL2001
CAS:SKL2001, an agonist of the Wnt/β-catenin pathway, can disrupt the Axin/β-catenin interaction.Formula:C14H14N4O3Purity:97.46% - 99.5%Color and Shape:SolidMolecular weight:286.29Ref: TM-T6989
5mg40.00€10mg60.00€25mg107.00€50mg185.00€100mg339.00€200mg510.00€500mg797.00€1mL*10mM (DMSO)66.00€KY1220
CAS:KY1220 destabilizes both β-catenin and Ras by targeting the Wnt/β-catenin pathway. It has an IC50 of 2.1 μM in HEK293 reporter cells.Formula:C14H10N4O3SPurity:99.66%Color and Shape:SolidMolecular weight:314.32Ref: TM-T15677
2mg46.00€5mg80.00€10mg117.00€25mg259.00€50mg374.00€100mg545.00€200mg740.00€1mL*10mM (DMSO)73.00€NRX-252262
CAS:NRX-252262 is a potent enhancer of the interaction between β-Catenin, and its cognate E3 ligase, SCFβ-TrCP, induces mutant β-catenin degradation(EC50:3.8 nM)Formula:C23H17Cl2F3N2O4SPurity:99.10% - 99.87%Color and Shape:SolidMolecular weight:545.36Ref: TM-T9182
1mg114.00€5mg273.00€10mg432.00€25mg715.00€50mg1,008.00€100mg1,359.00€1mL*10mM (DMSO)329.00€MSAB
CAS:MSAB inhibits Wnt/β-catenin by binding to β-catenin and inducing its breakdown.Formula:C15H15NO4SPurity:99.76%Color and Shape:SolidMolecular weight:305.35Ref: TM-T8710
1mg37.00€2mg49.00€5mg73.00€10mg119.00€25mg235.00€50mg354.00€100mg535.00€500mg1,121.00€1mL*10mM (DMSO)82.00€LP-922056
CAS:LP-922056 is an inhibitor of Notum Pectinacetylesterase with EC50 values of 21 nM, 55 nM for human and mouse, respectively.Formula:C11H9ClN2O2S2Purity:99.91%Color and Shape:SolidMolecular weight:300.78DK419
CAS:DK419 is an orally active inhibitor of Wnt/β-catenin signaling, with an IC50 of 0.19 μM.Formula:C16H8ClF6N3OPurity:98.15%Color and Shape:SolidMolecular weight:407.7NRX-252114
CAS:NRX-252114 promotes mutant β-catenin degradation, binding it to E3 ligase SCFβ-TrCP (EC50: 6.5 nM; Kd: 0.4 nM).Formula:C22H12Cl2F3N3O2SPurity:98.26%Color and Shape:SolidMolecular weight:510.32Dendrobium phenol
CAS:Gigantol is a novel inhibitor of the Wnt/β-catenin pathway.Formula:C16H18O4Purity:98.66% - 99.48%Color and Shape:SolidMolecular weight:274.31Ref: TM-TL0008
1mg49.00€2mg65.00€5mg97.00€10mg156.00€25mg255.00€50mg373.00€100mg555.00€1mL*10mM (DMSO)165.00€Pamidronic acid
CAS:Pamidronic acid Leads to Bone Necrosis via Suppression of Wnt/β-Catenin Signaling in Human Bone Marrow Mesenchymal Stem CellsFormula:C3H11NO7P2Purity:97.72%Color and Shape:SolidMolecular weight:235.07
