c-Kit
c-Kit inhibitors are compounds that block the activity of the Stem Cell Factor Receptor (c-Kit), a tyrosine kinase that plays a pivotal role in cell survival, proliferation, and differentiation, particularly in hematopoietic cells. Mutations in c-Kit are linked to various cancers, including gastrointestinal stromal tumors (GIST) and leukemia. At CymitQuimica, we provide c-Kit inhibitors to support your research in oncology, hematology, and stem cell biology.
Products of "c-Kit"
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AC710
CAS:AC710 is a potent PDGFR inhibitor (Kds: 0.6, 1, 1.57, 1.3, 1 nM for FLT3, KIT, CSF1R, PDGFRα and PDGFRβ).Formula:C31H42N6O4Purity:99.48%Color and Shape:SolidMolecular weight:562.7Sitravatinib
CAS:Sitravatinib (MGCD516) (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Met, c-Kit, PDGFRα/β, PDGFR, andFormula:C33H29F2N5O4SPurity:98.9% - 99.74%Color and Shape:SolidMolecular weight:629.68Ref: TM-T4349
5mg51.00€10mg79.00€25mg137.00€50mg210.00€100mg338.00€200mg535.00€500mg845.00€1mL*10mM (DMSO)72.00€N-Desmethyl imatinib
CAS:N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.Formula:C28H29N7OPurity:98.60%Color and Shape:Off-White To Pale-Yellow SolidMolecular weight:479.58Ref: TM-T11641
1mg92.00€5mg170.00€10mg319.00€25mg540.00€50mg777.00€100mg1,074.00€1mL*10mM (DMSO)178.00€Anti-CD117 Antibody (9H202)
Anti-CD117 Antibody (9H202) is an antibody targeting CD117. Anti-CD117 Antibody (9H202) can be used in ELISA, IHC, FCM.Color and Shape:Odour LiquidLenvatinib mesylate
CAS:Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities.Formula:C22H23ClN4O7SPurity:99.03% - 99.79%Color and Shape:SolidMolecular weight:522.96Midostaurin
CAS:PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.Formula:C35H30N4O4Purity:100% - 99.47%Color and Shape:SolidMolecular weight:570.64Ref: TM-T3211
1mg51.00€5mg88.00€10mg126.00€25mg216.00€50mg328.00€100mg487.00€500mg1,093.00€1mL*10mM (DMSO)96.00€Anti-C-Kit Antibody-APC (1R766)
Anti-C-Kit Antibody-APC (1R766) is a APC-conjugated Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody-APC (1R766) can be used in FCM.Color and Shape:Odour LiquidAnti-C-Kit Antibody-FITC (8E724)
Anti-C-Kit Antibody-FITC (8E724) is a FITC-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-FITC (8E724) can be used in FCM.Color and Shape:Odour Liquidc-Kit-IN-3
CAS:c-Kit-IN-3 is a selective inhibitor of c-KIT kinase with IC50s of 4 nM and 8 nM for c-Kit (wt) and c-Kit (T670I).Formula:C26H20ClF3N2O4Purity:99.43%Color and Shape:SolidMolecular weight:516.9Ref: TM-T10651
1mg87.00€5mg162.00€10mg254.00€25mg419.00€50mg562.00€100mg787.00€500mg1,578.00€1mL*10mM (DMSO)334.00€Dovitinib lactate
CAS:Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).Formula:C24H27FN6O4Purity:98.44% - 99.54%Color and Shape:SolidMolecular weight:482.51Ref: TM-T7104
5mg51.00€10mg79.00€25mg129.00€50mg213.00€100mg358.00€200mg535.00€500mg843.00€1mL*10mM (DMSO)57.00€CD117 Protein, Mouse, Recombinant (His)
The c-kit proto-oncogen (CD 117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells.Color and Shape:Lyophilized PowderMolecular weight:56.63 kDa (predicted). Due to glycosylation, the protein migrates to 75-100 kDa based on Tris-Bis PAGE result.Avapritinib
CAS:Avapritinib (BLU-285) is a selective, highly potent, and orally active inhibitor of KIT and PDGFRA activation loop mutant kinases.Cost-effective and quality-assured.Formula:C26H27FN10Purity:96.59% - 99.7%Color and Shape:SolidMolecular weight:498.56Ref: TM-T5109
1mg88.00€5mg187.00€10mg305.00€25mg520.00€50mg748.00€100mg1,026.00€500mg2,072.00€1mL*10mM (DMSO)205.00€AMG-25
CAS:AMG-25 (c-Kit-IN-5-1) is a c-Kit inhibitor that inhibits c-Kit, KDR, p38, Lck, and Src, and can be used for the study of mast cell-associated fibrotic diseases.Formula:C23H17N5O2Purity:98.16%Color and Shape:SolidMolecular weight:395.41c-Kit Protein, Human, Recombinant (aa 50-190, His)
c-Kit Protein, Human, Recombinant (aa 50-190, His) is expressed in E.Color and Shape:Lyophilized PowderMolecular weight:17.9 kDa (predicted); 18 kDa (reducing conditions)c-Kit Protein, Mouse, Recombinant (hFc)
c-Kit Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Color and Shape:Lyophilized PowderMolecular weight:82.5 kDa (predicted); 100-110 kDa (reducing condition, due to glycosylation)Anti-C-Kit Antibody-PE (7P530)
Anti-C-Kit Antibody-PE (7P530) is a PE-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-PE (7P530) can be used in FCM.Color and Shape:Odour LiquidCabozantinib
CAS:Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM).Formula:C28H24FN3O5Purity:99.59% - 99.88%Color and Shape:SolidMolecular weight:501.51Anti-C-Kit Antibody-FITC (7P530)
Anti-C-Kit Antibody-FITC (7P530) is a FITC-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-FITC (7P530) can be used in FCM.Color and Shape:Odour LiquidSU14813
CAS:SU14813: inhibits multiple kinases (VEGFR2, VEGFR1, PDGFRβ, KIT) with IC50s of 50, 2, 4, 15 nM; antiangiogenic and antitumor.Formula:C23H27FN4O4Purity:99.72%Color and Shape:SolidMolecular weight:442.48Tyrphostin AG1296
CAS:Tyrphostin AG1296 (Tyrphostin AG 1296) is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR.Formula:C16H14N2O2Purity:99.66% - 99.68%Color and Shape:SolidMolecular weight:266.29Ref: TM-T6711
2mg40.00€5mg58.00€10mg90.00€25mg180.00€50mg279.00€100mg411.00€200mg585.00€1mL*10mM (DMSO)81.00€
