Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Products of "Autophagy"
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3PO
CAS:3PO inhibits PFKFB3 (IC50: 22.9 µM) and cancer cell growth (IC50: 1.4-24 µM), reducing glucose uptake and key cellular metabolites.Formula:C13H10N2OPurity:97.76% - 99.67%Color and Shape:SolidMolecular weight:210.23Ref: TM-T22223
5mg57.00€10mg81.00€25mg127.00€50mg188.00€100mg340.00€200mg507.00€500mg807.00€1mL*10mM (DMSO)64.00€Emodin
CAS:Emodin, a plant-derived anthraquinone, inhibits Y cell growth via various signaling pathways.Formula:C15H10O5Purity:94.4% - 98.9%Color and Shape:Physical Description Orange Needles Or Powder (Ntp 1992)Molecular weight:270.24Cucurbitacin B
CAS:Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.Formula:C32H46O8Purity:97.10% - 99.33%Color and Shape:SolidMolecular weight:558.7EIPA
CAS:EIPA (L593754) is a TRPP3 channel inhibitor and an inhibitor of Na+/H+ exchange (NHE). EIPA inhibits megacytosis, promotes autophagy. Cost-effective and quality-assured.Formula:C11H18ClN7OPurity:96.62% - 98.52%Color and Shape:Off-White To Yellow SolidMolecular weight:299.76Schisandrol B
CAS:Schisandrol B fights neuroinflammation, liver/renal damage, and reduces cell growth via multiple signaling pathways.Formula:C23H28O7Purity:99.14% - 99.32%Color and Shape:SolidMolecular weight:416.46Ref: TM-T6S1917
5mg71.00€10mg96.00€25mg202.00€50mg303.00€100mg452.00€500mg1,035.00€1mL*10mM (DMSO)79.00€Mdivi-1
CAS:Mdivi-1 (Mitochondrial division inhibitor 1) is a mitochondrial division inhibitor that inhibits DRP1 and Dynamin I (IC50=1-10 μM).Formula:C15H10Cl2N2O2SPurity:96.57% - 99.6%Color and Shape:SolidMolecular weight:353.22Ref: TM-T1907
5mg47.00€10mg56.00€25mg90.00€50mg153.00€100mg227.00€200mg338.00€500mg558.00€1mL*10mM (DMSO)50.00€Turofexorate Isopropyl
CAS:Turofexorate Isopropyl (XL335) is a potent, selective, and orally bioavailable FXR agonist with EC50 of 4 nMFormula:C25H24F2N2O3Purity:99.33% - 99.73%Color and Shape:SolidMolecular weight:438.47ROC-325
CAS:ROC-325: orally active autophagy inhibitor with anticancer effects, induces kidney cancer cell death; selective action.Formula:C28H27ClN4OSPurity:99.26%Color and Shape:SolidMolecular weight:503.06Ref: TM-T16777
1mg35.00€2mg47.00€5mg64.00€10mg97.00€25mg188.00€50mg311.00€100mg449.00€500mgTo inquireOlaparib
CAS:View and buy Olaparib from TargetMol.Olaparib is a small molecule inhibitor of PARP1/PARP2.Cited in 10 publications.Formula:C24H23FN4O3Purity:100% - 99.90%Color and Shape:SolidMolecular weight:434.46Autophagy-IN-6
Autophagy-IN-6 (compound 1u) is an inhibitor of lysosomal autophagy that induces the accumulation of the LC3-II protein. Additionally, it exhibits antiproliferative activity.Formula:C28H43N3O3Color and Shape:SolidMolecular weight:469.66MRT68921
CAS:MRT68921 is a potent and dual autophagy kinase ULK1/2 inhibitor with IC50 of 2.9 nM and 1.1 nM, respectively.Formula:C25H34N6OPurity:99.23%Color and Shape:SolidMolecular weight:434.58Trimetazidine dihydrochloride
CAS:Trimetazidine, an anti-ischemic agent, enhances myocardial glucose use, inhibits fat metabolism, and helps with angina.Formula:C14H24Cl2N2O3Purity:99.58%Color and Shape:Crystalline SolidMolecular weight:339.258Dexamethasone acetate
CAS:Dexamethasone acetate (NSC 39471) is a potent anti-inflammatory steroid, blocks NF-kB, and lacks salt-retention.Formula:C24H31FO6Purity:99.22% - 99.65%Color and Shape:White Or Almost White Crystalline PowderMolecular weight:434.5Bardoxolone Methyl
CAS:Bardoxolone Methyl (TP-155) is a synthetic triterpenoid that acts as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway with potential anti-Formula:C32H43NO4Purity:97.81% - 99.09%Color and Shape:SolidMolecular weight:505.69Ref: TM-T6165
10mg47.00€25mg65.00€50mg88.00€100mg119.00€200mg187.00€500mg424.00€1mL*10mM (DMSO)50.00€FIPI
CAS:FIPI, a halopemide derivative, strongly blocks PLD1 and PLD2 (IC50s: 25 nM, 20 nM) and hinders PLD-mediated cell activity.Formula:C23H24FN5O2Purity:98.01% - 99.08%Color and Shape:SolidMolecular weight:421.47Etoposide
CAS:Etoposide (VP-16-213) is a topoisomerase II inhibitor that inhibits DNA synthesis by forming a complex with topoisomerase II and DNA (IC50=60.3 μM).Formula:C29H32O13Purity:99.19% - 99.94%Color and Shape:Crystals From Methanol SolidMolecular weight:588.56Diosgenin glucoside
CAS:Diosgenin glucoside (Trillin) and other synthetic glycosides with similar activities may be of use in the management of hypercholesterolemia and atherosclerosisFormula:C33H52O8Purity:97.17% - 99.44%Color and Shape:SolidMolecular weight:576.76Leonurine
CAS:Leonurine (SCM-198) is an alkaloid that has been found in H. leonuri and with anti-oxidative and anti-inflammatory.Formula:C14H21N3O5Purity:98.55%Color and Shape:White Crystalline PowderMolecular weight:311.33Pentoxifylline
CAS:Pentoxifylline (PTX) stimulates cytokines, inhibits phosphodiesterase, enhances blood flow, and increases cell flexibility.Formula:C13H18N4O3Purity:99.26% - 99.96%Color and Shape:SolidMolecular weight:278.31UM-164
CAS:UM-164 (DAS-DFGO-II), a highly potent c-Src inhibitor with a dissociation constant (Kd) of 2.7 nM, also effectively inhibits p38α and p38β.Formula:C30H31F3N8O3SPurity:98.72% - 99.52%Color and Shape:SolidMolecular weight:640.68
