Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Products of "Autophagy"
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CCT128930
CAS:'CCT128930, potent Akt2 inhibitor (IC50=6 nM), 28x more selective over PKA.'Formula:C18H20ClN5Purity:99.07% - 99.18%Color and Shape:SolidMolecular weight:341.84Ref: TM-T6303
2mg42.00€5mg65.00€10mg94.00€25mg170.00€50mg273.00€100mg409.00€200mg652.00€1mL*10mM (DMSO)71.00€Icariin
CAS:Icariin (Ieariline) is a flavonol glycoside that inhibits PDE5 and PDE4 activity and is a PPARα activator. Cost-effective and quality-assured.Formula:C33H40O15Purity:97.82% - 98.49%Color and Shape:SolidMolecular weight:676.66Irinotecan Hydrochloride
CAS:Irinotecan HCl, a camptothecin derivative prodrug, becomes active metabolite SN-38, inhibiting topoisomerase I to trigger apoptosis.Formula:C33H39ClN4O6Purity:98% - 99.94%Color and Shape:Yellow Crystalline PowderMolecular weight:623.14Ref: TM-T0486L
10mg35.00€25mg52.00€50mg69.00€100mg95.00€200mg136.00€500mg268.00€1mL*10mM (DMSO)74.00€Nicardipine hydrochloride
CAS:Nicardipine hydrochloride is a potent calcium channel blocker used to dilate cerebral and coronary vessels.Formula:C26H30ClN3O6Purity:99.58% - 99.89%Color and Shape:Yellow SolidMolecular weight:515.99Verteporfin
CAS:Verteporfin (BPD-MA) is a YAP inhibitor that inhibits YAP-TEAD interactions.Formula:C41H42N4O8Purity:95.37% - 99.82%Color and Shape:Dark Green To Black SolidMolecular weight:718.79Ref: TM-T3112
1mg40.00€2mg51.00€5mg85.00€10mg115.00€25mg225.00€50mg365.00€100mg462.00€1mL*10mM (DMSO)120.00€BL-918
CAS:BL-918 is a potent activator of UNC-51-like kinase 1 (ULK1) with an EC50 of 24.14 nM.Formula:C23H15F8N3OSPurity:99.11% - 99.40%Color and Shape:SolidMolecular weight:533.44Ref: TM-T8322
1mg49.00€2mg70.00€5mg104.00€10mg156.00€25mg284.00€50mg455.00€100mg747.00€500mg1,501.00€1mL*10mM (DMSO)127.00€4E1rcat
CAS:4E1RCat is a dual inhibitor of eIF4E:eIF4 g and eIF4E:4E-BP1 interaction. And it inhibits the binding of eIF4 g to eIF4E with IC50 of 3.2 μM.Formula:C28H18N2O6Purity:99.36%Color and Shape:SolidMolecular weight:478.45Atezolizumab
CAS:Atezolizumab is an antibody inhibitor, a humanized monoclonal antibody, IgG1, which targets PD-L1. Atezolizumab has antitumor effect. Cost-effective and quality-assured.Purity:95.10% - 99.3% （SEC-HPLC）Color and Shape:LiquidMolecular weight:145 kDaTamibarotene
CAS:Tamibarotene (Amnolake) is an orally active, synthetic retinoid, developed to overcome all-trans retinoic acid (ATRA) resistance, with potential antineoplasticFormula:C22H25NO3Purity:97.22% - 98.2%Color and Shape:Crystalline SolidMolecular weight:351.44Ref: TM-T6694
1g369.00€10mg47.00€25mg64.00€50mg79.00€100mg97.00€200mg153.00€500mg249.00€1mL*10mM (DMSO)47.00€PF-06454589
CAS:PF-06454589 is a potent inhibitor of LRRK2.Formula:C14H16N6OPurity:99.06%Color and Shape:SolidMolecular weight:284.32Ref: TM-T7729
2mg35.00€5mg50.00€10mg80.00€25mg135.00€50mg197.00€100mg306.00€200mg442.00€1mL*10mM (DMSO)55.00€Deguelin
CAS:Deguelin ((-)-Deguelin) is a PI3K/AKT Inhibitor, which is a natural product isolated from plants in the Mundulea sericea family.Formula:C23H22O6Purity:96.39% - 99.29%Color and Shape:SolidMolecular weight:394.42Idarubicin hydrochloride
CAS:Idarubicin hydrochloride (Zavedos), a hydrochloride salt form of Idarubicin, is a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells ( IC50: 3.3 ng/mL).Formula:C26H27NO9·HClPurity:100% - 99.93%Color and Shape:SolidMolecular weight:533.95Ancitabine hydrochloride
CAS:Ancitabine hydrochloride (NSC 145668 HCl) is the hydrochloride salt of a cytarabine congener prodrug with antineoplastic activity.Formula:C9H12ClN3O4Purity:99.02% - 99.37%Color and Shape:White SolidMolecular weight:261.66SMER28
CAS:SMER28 triggers autophagy in cells without mTOR, blocking amyloid beta buildup.Formula:C11H10BrN3Purity:99.94% - 99.97%Color and Shape:SolidMolecular weight:264.12Ref: TM-T3155
5mg51.00€10mg73.00€25mg127.00€50mg235.00€100mg452.00€200mg660.00€500mg1,035.00€1mL*10mM (DMSO)51.00€Sapanisertib
CAS:Sapanisertib (INK 128) is an oral raptor-mTOR and rictor-mTOR inhibitor with potential cancer-fighting properties.Formula:C15H15N7OPurity:100% - 99.67%Color and Shape:SolidMolecular weight:309.33Ref: TM-T1838
1mg40.00€2mg51.00€5mg85.00€10mg96.00€25mg160.00€50mg235.00€100mg350.00€500mg838.00€1mL*10mM (DMSO)88.00€DPN
CAS:DPN (Diarylpropionitrile) is an selective agonist of estrogen receptor β (ERβ) .Formula:C15H13NO2Purity:99.01%Color and Shape:Off-White SolidMolecular weight:239.27Memantine hydrochloride
CAS:Memantine hydrochloride (Memantine HCl) is an AMANTADINE derivative that has some dopaminergic effects.Formula:C12H22ClNPurity:99.56% - 99.96%Color and Shape:Crystalline SolidMolecular weight:215.763Britannin
CAS:Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells.Formula:C19H26O7Purity:98% - 98.53%Color and Shape:SolidMolecular weight:366.41Oxyphenisatin acetate
CAS:Oxyphenisatin acetate inhibits the growth of the breast cancer cell lines MCF7, T47D, HS578T, and MDA-MB-468.Formula:C24H19NO5Purity:98% - 98.62%Color and Shape:SolidMolecular weight:401.41Baicalin
CAS:Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIVFormula:C21H18O11Purity:90.08% - 99.25%Color and Shape:Yellow PowderMolecular weight:446.36
