Autophagy
Autophagy inhibitors target the cellular process of autophagy, which involves the degradation and recycling of cellular components through lysosomes. Autophagy is a critical mechanism for maintaining cellular homeostasis, but its dysregulation is implicated in various diseases, including cancer, neurodegeneration, and infections. Inhibitors of autophagy can block this process, making them valuable tools for studying the role of autophagy in disease and developing therapeutic strategies. At CymitQuimica, we offer autophagy inhibitors to support your research in cell biology, oncology, and neurodegenerative diseases.
Products of "Autophagy"
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Hoechst 33342
CAS:Hoechst 33342: a benzimidazole dye, DNA stain for AT-rich regions, cell-permeable, quantifies DNA in live cells.Formula:C27H28N6OPurity:98.45% - 99.57%Color and Shape:Yellow-Green PowderMolecular weight:452.55Retinoic acid
CAS:Retinoic acid (Tretinoin) binds to and activates RARs, thereby inducing changes in gene expression that lead to inhibition of tumorigenesis.Formula:C20H28O2Purity:97.21% - 99.6%Color and Shape:Yellow-Orange PowderMolecular weight:300.44Crenolanib
CAS:Crenolanib (ARO 002) is an orally bioavailable type III tyrosine kinases inhibitor of PDGFRα/β and FLT3 (IC50s: 11, 3.2, and 4 nM).Formula:C26H29N5O2Purity:97.45% - 99.28%Color and Shape:SolidMolecular weight:443.54SBI-0206965
CAS:SBI-0206965 is a potent, selective and cell-permeable autophagy kinase ULK1 inhibitor with IC50 of 108 nM for ULK1 kinase activity and 711 nM for ULK2.Formula:C21H21BrN4O5Purity:99.13%Color and Shape:SolidMolecular weight:489.32DAPT
CAS:DAPT (LY-374973) is a γ-secretase inhibitor that inhibits total Aβ and Aβ42 (IC50=115/200 nM) and is orally active.Formula:C23H26F2N2O4Purity:98.06% - 99.81%Color and Shape:White SolidMolecular weight:432.46Ref: TM-T6202
5mg58.00€10mg88.00€25mg165.00€50mg279.00€100mg414.00€200mg517.00€500mg835.00€1mL*10mM (DMSO)59.00€Omeprazole Sodium
CAS:Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion.Formula:C17H18N3NaO3SPurity:99.57%Color and Shape:Clear In WaterMolecular weight:367.4SR-3677
CAS:SR-3677 is an effective and specific inhibitor of ROCK2 (IC50: 3 nM).Formula:C22H24N4O4Purity:98.46%Color and Shape:SolidMolecular weight:408.45H-89 dihydrochloride
CAS:H-89 dihydrochloride (5-Isoquinolinesulfonamide) is a potent inhibitor of protein kinase A (PKA; IC50: 0.14 μM, Ki: 48 nM).Formula:C20H20BrN3O2S·2HClPurity:100% - 99.40%Color and Shape:SolidMolecular weight:519.28Ref: TM-T6250
5mg39.00€10mg58.00€25mg106.00€50mg202.00€100mg344.00€200mg512.00€500mg815.00€1mL*10mM (DMSO)52.00€Meloxicam
CAS:Meloxicam (Metacam) is a Nonsteroidal Anti-inflammatory Drug.Formula:C14H13N3O4S2Purity:97.09% - 99.60%Color and Shape:Light Yellow SolidMolecular weight:351.4Autogramin-2
CAS:Autogramin-2 (tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate) potently inhibits autophagy induced by eitherFormula:C21H27N3O4SPurity:96.25%Color and Shape:SolidMolecular weight:417.52AS-605240
CAS:AS-605240 is an effective and specific inhibitor of PI3Kγ (IC50/Ki: 87.8 nM).Formula:C12H7N3O2SPurity:97% - 99.91%Color and Shape:SolidMolecular weight:257.27PTC-209
CAS:PTC-209 is a potent and selective BMI-1 inhibitor.Formula:C17H13Br2N5OSPurity:99.43% - 99.60%Color and Shape:SolidMolecular weight:495.19Curcumin
CAS:Curcumin (Natural Yellow 3) is a phenolic natural product, an inhibitor of histone acetyltransferase p300/CREB (IC50=25 μM) with specificity.Formula:C21H20O6Purity:95% - 98.98%Color and Shape:Orange-Yellow Crystal Powder; Gives Brownish-Red Color With Alkali; Light-Yellow Color With Acids Physical Description Orange-Yellow Needles (Ntp 1992)Molecular weight:368.3799JH-II-127
CAS:JH-II-127 is an oral LRRK2 inhibitor with IC50s: 6.6 nM (WT), 2.2 nM (G2019S), 47.7 nM (A2016T).Formula:C19H21ClN6O3Purity:98.32%Color and Shape:SolidMolecular weight:416.86Pantoprazole
CAS:Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal refluxFormula:C16H15F2N3O4SPurity:99.28% - 99.63%Color and Shape:Almost White SolidMolecular weight:383.37MAO-B-IN-26
CAS:MAO-B-IN-26 (Compound IC9) serves as both a MAO-B and acetylcholinesterase inhibitor.Formula:C17H12BrNOPurity:98%Color and Shape:SolidMolecular weight:326.19Tea polyphenol
CAS:Tea polyphenol, also called green tea extract, are a mixture of chemical compounds, such as flavanoids and tannins, found naturally in tea.Formula:C17H19N3OPurity:98%Color and Shape:Yelloish Green Free Flowing PowderMolecular weight:281.36Venetoclax
CAS:Venetoclax (ABT-199) is a selective inhibitor of Bcl-2 (Ki < 0.010 nM), binding over 3 orders of magnitude less avidly to Bcl-xL, and Bcl-W (Kis = 48/245 nM).Formula:C45H50ClN7O7SPurity:98% - 99.96%Color and Shape:SolidMolecular weight:868.44LY2109761
CAS:LY2109761: a TGF-β dual inhibitor, Ki=38 nM (TβRI) & 300 nM (TβRII), hinders Smad2 phosphorylation.Formula:C26H27N5O2Purity:97% - 99.83%Color and Shape:SolidMolecular weight:441.52Ref: TM-T2123
2mg47.00€5mg70.00€10mg111.00€25mg188.00€50mg335.00€100mg507.00€200mg730.00€1mL*10mM (DMSO)77.00€
