S1P Receptor
Sphingosine-1-phosphate (S1P) receptors are a family of GPCRs that bind to the lipid signaling molecule sphingosine-1-phosphate. These receptors play critical roles in immune cell trafficking, vascular development, and maintaining the integrity of endothelial barriers. S1P receptor modulators are being developed for the treatment of multiple sclerosis, cancer, and cardiovascular diseases due to their ability to influence immune responses and cell migration. At CymitQuimica, we offer a variety of high-quality S1P receptor modulators to support your research in immunology, oncology, and vascular biology.
Products of "S1P Receptor"
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TY-52156
CAS:TY-52156 is an effective and selective S1P3 receptor antagonist (Ki: 110 nM).Formula:C18H19Cl2N3OPurity:99.91%Color and Shape:SolidMolecular weight:364.27Ref: TM-T17183
2mg40.00€5mg60.00€10mg87.00€25mg166.00€50mg298.00€100mg510.00€200mg683.00€1mL*10mM (DMSO)66.00€N,N-Dimethylsphingosine
CAS:N,N-Dimethylsphingosine,is a potent competitive SphK phosphorylation inhibitor.DMS is elevated in models of neuropathic pain by increasing IL-1β and MCP-1.Formula:C20H41NO2Purity:98%Color and Shape:Clear Colorless To Faint Yellow Liquid/White To Off-White PowderMolecular weight:327.55S1p receptor agonist 1
CAS:S1p receptor agonist 1 (S1p-receptor-agonist-1) is an S1P receptor agonist.Formula:C23H24FN3O3Purity:99.07% - 99.90%Color and Shape:SolidMolecular weight:409.45Ozanimod
CAS:Ozanimod (RPC-1063) (RPC1063) is a specific oral S1P Receptor 1 modulator.Formula:C23H24N4O3Purity:98.68% - 99.58%Color and Shape:SolidMolecular weight:404.46Ref: TM-T6923
1mg48.00€5mg96.00€10mg144.00€25mg283.00€50mg454.00€100mg655.00€200mg929.00€500mg1,378.00€1mL*10mM (DMSO)96.00€GSK2018682
CAS:GSK2018682 is an agonist of sphingosine-1-phosphate receptor (s1p1) and (s1p5) agonist(pEC50s of 7.7 and 7.2,respectively).Formula:C22H21ClN4O4Purity:99.04%Color and Shape:SolidMolecular weight:440.88W140 HBr
CAS:[(3S)-3-amino-4-(3-hexylanilino)-4-oxobutyl]phosphonic acid;hydrobromide is a S1P1 antagonist with Ki of 2.84 μM.Formula:C16H28BrN2O4PPurity:99.34%Color and Shape:SoildMolecular weight:423.28Ref: TM-T60204
1mg115.00€2mg172.00€5mg255.00€10mg375.00€25mg562.00€50mg787.00€100mg1,074.00€1mL*10mM (DMSO)284.00€SK1-IN-1
CAS:SK1-IN-1 is a SPHK1 inhibitor (IC50: 58 nM), with potential anticancer activity, and can be used to study cancer and neurodegenerative diseases.Formula:C22H30N4O3Purity:98.72%Color and Shape:SolidMolecular weight:398.5BMS-960
CAS:BMS-960 is an S1P agonist with potential anti-tumour activity for cancer research.Formula:C26H23F3N4O5Purity:97.74% - 99.28%Color and Shape:SolidMolecular weight:528.48CYM-5541
CAS:CYM-5541 (ML249) is a selective and allosteric S1P3 receptor agonist.Formula:C19H28N2O2Purity:97.34% - 98.39%Color and Shape:SolidMolecular weight:316.44Ref: TM-T3961
2mg38.00€5mg57.00€10mg92.00€25mg160.00€50mg254.00€100mg373.00€500mg873.00€1mL*10mM (DMSO)64.00€ASP-4058
CAS:ASP-4058: Safe, oral S1P1/S1P5 agonist; improves autoimmune encephalomyelitis in mice.Formula:C19H12F6N4O2Purity:99.5% - 99.51%Color and Shape:SolidMolecular weight:442.31Siponimod
CAS:Siponimod (BAF312) modulates S1P1/S1P5 with EC50s of 0.39/0.98 nM; >1000x selectivity over S1P2-4.Formula:C29H35F3N2O3Purity:97.08% - 99.40%Color and Shape:SolidMolecular weight:516.59Cenerimod
CAS:Cenerimod (ACT-334441) is an S1P1 agonist used in the study of murine experimental autoimmune encephalomyelitis (EAE) and murine scleroderma.Formula:C25H31N3O5Purity:97.43% - 99.97%Color and Shape:SolidMolecular weight:453.53SphK1&2-IN-1
CAS:SphK1&2-IN-1 is a sphingosine kinase inhibitor with anti-inflammatory, antitumor and hemostatic effects.Formula:C14H14N2O3SPurity:99.27%Color and Shape:SolidMolecular weight:290.34GLPG2938
CAS:GLPG2938 (1-(2-Ethoxy-6-(trifluoromethyl)pyridin-4-yl)-3-((5-methyl-6-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)pyridazin-3-yl)methyl)urea) is a potent andFormula:C20H19F6N7O2Purity:98.25%Color and Shape:SolidMolecular weight:503.4Ref: TM-T9199
1mg84.00€5mg153.00€10mg264.00€25mg550.00€50mg792.00€100mg1,093.00€200mg1,454.00€1mL*10mM (DMSO)166.00€Vibozilimod
CAS:Vibozilimod (SCD-044) is S1P receptor-1 (S1PR1) agonist .Formula:C29H36ClN3O5Purity:99.47%Color and Shape:SolidMolecular weight:542.07SAR-114137
CAS:SAR-114137 is a histone sphingomyelin kinase inhibitor used in the study of molluscum arteriosum and peripheral neuropathic pain.Formula:C25H34N4O7SPurity:100% - 99.57%Color and Shape:SolidMolecular weight:534.63MHP
CAS:MHP (Methyl caprooyl tyrosinate) is an activator of sphingosine kinase (SPHK1), and significantly stimulates CAMP mRNA and protein production in KC.Formula:C16H23NO4Purity:98.58%Color and Shape:SolidMolecular weight:293.36Ref: TM-T4658
1mg47.00€2mg64.00€5mg111.00€10mg188.00€25mg376.00€50mg563.00€100mg800.00€1mL*10mM (DMSO)127.00€CS 2100
CAS:CS 2100 (1-[[4-Ethyl-5-[5-(4-phenoxyphenyl)-1,2,4-oxadiazol-3-yl]-2-thienyl]methyl]-3-azetidinecarboxylic acid) is an S1P1 agonist.Formula:C25H23N3O4SPurity:98.13%Color and Shape:SolidMolecular weight:461.53VPC 23019
CAS:VPC 23019 is a competitive antagonist at the S1P1 and S1P3 receptors (pKi= 7.86 and 5.93, respectively).Formula:C17H29N2O5PPurity:98%Color and Shape:SolidMolecular weight:372.4AMG-369
CAS:AMG-369 (AMG 247) is an S1P1/S1P5 dual agonist that delays the development of experimental autoimmune encephalomyelitis in rats.Formula:C26H22FN3O2SPurity:98.39% - 98.92%Color and Shape:SolidMolecular weight:459.54
