S1P Receptor
Sphingosine-1-phosphate (S1P) receptors are a family of GPCRs that bind to the lipid signaling molecule sphingosine-1-phosphate. These receptors play critical roles in immune cell trafficking, vascular development, and maintaining the integrity of endothelial barriers. S1P receptor modulators are being developed for the treatment of multiple sclerosis, cancer, and cardiovascular diseases due to their ability to influence immune responses and cell migration. At CymitQuimica, we offer a variety of high-quality S1P receptor modulators to support your research in immunology, oncology, and vascular biology.
Products of "S1P Receptor"
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Amgen-23
CAS:Amgen-23 is a selective and highly potent sphingosine kinase 1 (SPHK1) inhibitor that inhibits SPHK2 and can be used in anticancer research.Formula:C23H25Cl2N3O2SPurity:97.31%Color and Shape:SolidMolecular weight:478.44Opaganib
CAS:Opaganib (ABC294640) is an orally active and specific sphingosine kinase-2 (SphK2) inhibitor (IC50: 60 μM).Formula:C23H25ClN2OPurity:98.86% - 99.85%Color and Shape:SolidMolecular weight:380.91Ref: TM-T6750
1mg40.00€2mg52.00€5mg85.00€10mg124.00€25mg240.00€50mg415.00€100mg615.00€1mL*10mM (DMSO)87.00€Ponesimod
CAS:Ponesimod (ACT-128800) is an orally available sphingosine-1-phosphate receptor 1 (S1PR1, S1P1) agonist with potential immunomodulating activity.Formula:C23H25ClN2O4SPurity:98.22% - 99.42%Color and Shape:SolidMolecular weight:460.97Ref: TM-T3258
1mg46.00€2mg59.00€5mg93.00€10mg131.00€25mg234.00€50mg404.00€100mg597.00€500mg1,283.00€1mL*10mM (DMSO)97.00€CYM-5520
CAS:CYM-5520 is a noncompetitive allosteric agonist of S1P2Formula:C21H19N3O2Purity:99.47%Color and Shape:SolidMolecular weight:345.39Ref: TM-T22703
1mg48.00€2mg64.00€5mg94.00€10mg142.00€25mg250.00€50mg374.00€100mg557.00€1mL*10mM (DMSO)103.00€PF429242 dihydrochloride
CAS:PF429242 dihydrochloride can reversibly inhibit S1P (IC50 of 175 nM).Formula:C25H37Cl2N3O2Purity:98.67%Color and Shape:SolidMolecular weight:482.49MP-A08
CAS:MP-A08 selectively inhibits SPHK1; targets SphK1 & SphK2 with Ki of 6.9 μM & 27 μM, respectively.Formula:C27H25N3O4S2Purity:98.04%Color and Shape:SolidMolecular weight:519.64CYM5442
CAS:CYM5442 is an S1P agonist, targeting to Sphingosine.Formula:C23H27N3O4Purity:96.65% - 97.57%Color and Shape:SolidMolecular weight:409.48SLM6031434 HCl
CAS:SLM6031434 HCl (SLM-6031434 HCl) is a SphK2 inhibitor that reduces LPS-induced TNF伪 and IL-1尾 production.Formula:C22H31ClF3N5O2Purity:98%Color and Shape:SolidMolecular weight:489.96Etrasimod
CAS:Etrasimod (APD334) is a specific and orally available antagonist of the sphingosine-1-phosphate-1 (S1P1) receptor (IC50: 1.88 nM in CHO cells).Formula:C26H26F3NO3Purity:99.17% - 99.77%Color and Shape:SolidMolecular weight:457.48Ref: TM-TQ0227
1mg52.00€5mg111.00€10mg180.00€25mg243.00€50mg305.00€100mg424.00€1mL*10mM (DMSO)113.00€K6PC-5
CAS:K6PC-5 is a ceramide derivative that acts as an activator of sphingosine kinase 1 (SPHK1), inducing a swift and temporary rise in intracellular calcium levels.Formula:C19H37NO4Purity:98.55%Color and Shape:SolidMolecular weight:343.5SK1-I hydrochloride
CAS:SK1-I hydrochloride is a selective and competitive SphK1 inhibitor and sphingosine analog ,anti-leukemic to inhibit tumor cell growth and promote apoptosis.Formula:C17H28ClNO2Purity:99.80%Color and Shape:SolidMolecular weight:313.86TASP 0277308
CAS:NH2-UAMC1110 TFA is an aminobutoxy derivative of UAMC1110 used in the synthesis of FAPI-QS. UAMC1110 is a fibroblast activating protein (fap) inhibitor.Formula:C23H28Cl2N6O3SColor and Shape:SolidMolecular weight:539.48LX-2931
CAS:LX-2931(LX-3305) is a sphingosine-1-phosphate cleavage enzyme (S1P) inhibitor for the treatment of rheumatoid arthritis.Formula:C9H15N3O5Purity:100% - 99.83%Color and Shape:SolidMolecular weight:245.23SEW2871
CAS:SEW 2871 is an orally available, highly selective S1P1 agonist. It activates ERK, Akt and Rac signaling pathways and induces S1P1 internalization and recycling.Formula:C20H10F6N2OSPurity:99.62%Color and Shape:White SolidMolecular weight:440.36CYM50374
CAS:CYM50374 inhibits Sphingosine-1-phosphate receptor 4 (S1P4 ) with an IC50 of µM.Formula:C19H19NO3SPurity:98.4% - 98.49%Color and Shape:SolidMolecular weight:341.42Ref: TM-T27106
1mg333.00€5mg787.00€10mg1,074.00€25mg1,510.00€50mg1,882.00€100mg2,375.00€500mg4,655.00€ML-031
CAS:ML-031 activated S1P2 with an EC50 value of 1 μM in an S1P reporter assay.Formula:C19H20N2O3Purity:99.21%Color and Shape:SolidMolecular weight:324.374-Deoxypyridoxine hydrochloride
CAS:4-Deoxypyridoxine HCl halts S1P breakdown by blocking SPL, reducing apoptosis in insulinoma cells like S1P.Formula:C8H12ClNO2Purity:99.86%Color and Shape:White To Off White Crystalline PowderMolecular weight:189.64Amiselimod hydrochloride
CAS:Amiselimod hydrochloride (MT-1303 hydrochloride) is a sphingosine 1-phosphate receptor-1 (S1P1) modulator.Formula:C19H31ClF3NO3Purity:99.55%Color and Shape:SolidMolecular weight:413.9Ref: TM-T10305
1mg38.00€2mg49.00€5mg80.00€10mg120.00€25mg215.00€50mg354.00€100mg512.00€200mg738.00€1mL*10mM (DMSO)88.00€Ozanimod hydrochloride
CAS:Ozanimod (RPC-1063) HCl is a selective S1P1/S1P5 modulator with high affinity, used in relapsing MS research.Formula:C23H25ClN4O3Purity:99.81%Color and Shape:SolidMolecular weight:440.92Ref: TM-T62552
1mg66.00€5mg139.00€10mg202.00€25mg416.00€50mg652.00€100mg938.00€500mg1,872.00€1mL*10mM (DMSO)154.00€CYM50308
CAS:CYM50308 is a high affinity agonist of sphingosine-1-phosphate receptor 4 (S1P4-R) (EC50: 56 nM).Formula:C20H21F2N3O2SPurity:99.43% - 99.63%Color and Shape:SolidMolecular weight:405.46Ref: TM-T15032
1mg62.00€5mg140.00€10mg202.00€25mg324.00€50mg455.00€100mg597.00€200mg842.00€500mg1,225.00€
