PI3K/Akt/mTOR Signaling
PI3K/Akt/mTOR signaling inhibitors are compounds that target the phosphoinositide 3-kinase (PI3K), Akt kinase, and mammalian target of rapamycin (mTOR) pathways. These pathways are critical regulators of cell growth, survival, metabolism, and autophagy, making them key targets in cancer research and metabolic disorders. Inhibiting these pathways can help to control tumor growth and proliferation, offering potential therapeutic strategies for various cancers and other diseases characterized by dysregulated cell signaling. At CymitQuimica, we offer a comprehensive selection of high-quality PI3K/Akt/mTOR inhibitors to support your research in oncology, cellular signaling, and metabolic diseases.
Subcategories of "PI3K/Akt/mTOR Signaling"
Show 2 more subcategories
Products of "PI3K/Akt/mTOR Signaling"
Sort by
Anti-EGFR Antibody (7X976)
Anti-EGFR Antibody (7X976) is an antibody targeting EGFR. Anti-EGFR Antibody (7X976) can be used in ELISA, WB, IHC, IF, FCM.Color and Shape:Odour LiquidTMBIM6 antagonist-1
CAS:TMBIM6 antagonist-1 (BAX-inhibitor-1) is a bax inhibitorFormula:C15H12N2O3Purity:99.26%Color and Shape:SolidMolecular weight:268.27Ref: TM-T8649
1mg93.00€2mg120.00€5mg187.00€10mg315.00€25mg567.00€50mg810.00€100mg1,111.00€500mg2,232.00€1mL*10mM (DMSO)202.00€AZD1080
CAS:AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor.Formula:C19H18N4O2Purity:97.72% - 99.75%Color and Shape:SolidMolecular weight:334.37Ref: TM-T1741
1mg43.00€2mg56.00€5mg85.00€10mg124.00€25mg219.00€50mg350.00€100mg429.00€1mL*10mM (DMSO)63.00€GSK-3 inhibitor 1
CAS:GSK-3 inhibitor 1 is a GSK-3 inhibitor.Formula:C22H17ClFN5O2Purity:98.11%Color and Shape:SolidMolecular weight:437.85Ref: TM-T11468
1mg104.00€5mg216.00€10mg354.00€25mg677.00€50mg1,008.00€100mg1,491.00€1mL*10mM (DMSO)240.00€Calotatug ginistinag
CAS:Calotatug ginistinag (XMT-2056) is an antibody-drug conjugate (ADC) aimed at targeting HER2. It is connected by a linker (XMT-1519 conjugate-1) to an effective payload that includes a STING agonist (STING agonist-20), presenting potential in immune activation and anti-tumor activity.Color and Shape:LiquidEGFR vIII Protein, Human, Recombinant (hFc)
EGFR vIII Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag.Color and Shape:Lyophilized PowderMolecular weight:90-120 KDa (reducing condition)EHT 1610
CAS:EHT 1610 (EHT 5372) is a potent inhibitor of DYRK, with an IC50 of 0.36 nM and 0.59 nM for DYRK1A and DYRK1B, respectively.Formula:C18H14FN5O2SPurity:98.27%Color and Shape:SolidMolecular weight:383.4PS47
CAS:PS-47(PS 47) is an inactive E-isomer of PS48. PS48 is an activator of PDK1.Formula:C17H15ClO2Purity:99.09%Color and Shape:SolidMolecular weight:286.75Ref: TM-T24677
5mg46.00€10mg65.00€25mg123.00€50mg187.00€100mg309.00€200mg435.00€1mL*10mM (DMSO)65.00€GSK-3 inhibitor 3
CAS:GSK-3 inhibitor 3 is a selective, orally active, brain-permeable GSK-3 inhibitor that inhibits GSK-3α and GSK-3β with IC50s of 0.35 nM and 0.25 nM, respectivelyFormula:C23H15FN6OPurity:98.36%Color and Shape:SoildMolecular weight:410.4MHY-1685
CAS:MHY-1685 is a mammalian target of rapamycin (mTOR) inhibitor and a senescence inhibitor that can rejuvenate senile hCSCs by modulating autophagy.Formula:C11H8N2O4Purity:98.44%Color and Shape:SolidMolecular weight:232.19SU5204
CAS:SU5204 (3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one), an analogue of SU5025, pharmacologically inhibits VEGFR2(IC50s of 4 and 51.5 μM for FLK-1 (VEGFR-2) andFormula:C17H15NO2Purity:99.46%Color and Shape:SolidMolecular weight:265.31O-304
CAS:O-304 is a pan-activator of AMP-activated protein kinase (AMPK).Formula:C16H11Cl2N3O2SPurity:99.80% - ≥98%Color and Shape:SolidMolecular weight:380.25Ref: TM-T7362
1mg66.00€2mg96.00€5mg144.00€10mg216.00€25mg432.00€50mg638.00€100mg908.00€500mg1,825.00€1mL*10mM (DMSO)159.00€NS-062
CAS:NS-062 is an orally effective, irreversible covalent inhibitor targeting EGFR, demonstrating antiproliferative activity in the resistant double mutant H1975 cells with an IC50 of 0.19 μM. It also exhibits antitumor activity in a murine H1975 xenograft model.Formula:C28H30Cl2F2N6O4Color and Shape:SolidMolecular weight:623.48A-769662
CAS:A-769662 is an effective, reversible AMPK activator(EC50=0.8 μM).Formula:C20H12N2O3SPurity:97.52% - 99.58%Color and Shape:SolidMolecular weight:360.39Ref: TM-T2468
2mg39.00€5mg57.00€10mg79.00€25mg142.00€50mg256.00€100mg465.00€500mg1,017.00€1mL*10mM (DMSO)59.00€TAK-285
CAS:TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc.Formula:C26H25ClF3N5O3Purity:99.17%Color and Shape:SolidMolecular weight:547.965-Bromo-3-indoxylacetate
CAS:5-Bromo-3-indoxylacetate acts as an inhibitor of GSK-3, with a pIC50 value of 3.39.Formula:C10H8BrNO2Color and Shape:SolidMolecular weight:254.08MELK-8a Dihydrochloride
MELK-8a Dihydrochloride is a useful organic compound for research related to life sciences and the catalog number is T35342.Purity:98%Color and Shape:SolidDNA-PK-IN-10
CAS:DNA-PK-IN-10 is a DNA-PK inhibitor utilized in the research of breast cancer and non-small cell lung cancer [1].Formula:C25H28N6O2Purity:98%Color and Shape:SolidMolecular weight:444.53CP-724714
CAS:CP-724714 (CP724714) is an effective and selective HER2/ErbB2 inhibitor (IC50: 10 nM), >640-fold selectivity against EGFR, Abl, InsR, PDGFR, IRG-1R, Src, VEGFR2Formula:C27H27N5O3Purity:97.10% - 98.82%Color and Shape:SolidMolecular weight:469.54Ref: TM-T4014
1mg44.00€2mg58.00€5mg95.00€10mg157.00€25mg273.00€50mg454.00€100mg660.00€1mL*10mM (DMSO)89.00€EAI001
CAS:EAI001 is a potent and selective mutant epidermal growth factor receptor (EGFR) variant inhibitor that inhibits EGFRL858R/T790M with an IC50 value of 24 nM.Formula:C19H15N3O2SPurity:100%Color and Shape:SolidMolecular weight:349.41
