AMPK
AMPK inhibitors are compounds that target and inhibit AMP-Activated Protein Kinase (AMPK), an enzyme that plays a critical role in cellular energy homeostasis. AMPK is activated in response to low energy levels in cells and helps regulate processes such as glucose uptake, fatty acid oxidation, and mitochondrial biogenesis. Inhibiting AMPK is important for studying its role in metabolic diseases, cancer, and aging. At CymitQuimica, we offer a range of AMPK inhibitors to support your research in metabolism, oncology, and age-related diseases.
Products of "AMPK"
Sort by
Dorsomorphin
CAS:Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive.Formula:C24H25N5OPurity:98% - 99.06%Color and Shape:SolidMolecular weight:399.49YKL-06-061
CAS:YKL-06-061 is a selective salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56 nM/1.77 nM/20.5 nM for SIK1/2/3, respectively.Formula:C30H37N7O2Purity:99.52% - 99.79%Color and Shape:SolidMolecular weight:527.66Flufenamic acid
CAS:Flufenamic acid (Arlef) is an anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties.Formula:C14H10F3NO2Purity:98.68%Color and Shape:White To Light Yellow Crystalline PowderMolecular weight:281.23Daphnetin
CAS:Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),Formula:C9H6O4Purity:97.47% - 99.8%Color and Shape:SolidMolecular weight:178.14MARK4 inhibitor 1
CAS:MARK4 inhibitor 1 inhibits cancer cell proliferation, metastasis and induces apoptosis.Formula:C20H18N6O3Purity:97.70%Color and Shape:SolidMolecular weight:390.4TMPA
CAS:TMPA is a nuclear receptor Nur77 and LKB1 interaction antagonist.Formula:C21H32O6Purity:98.08%Color and Shape:SolidMolecular weight:380.48Ref: TM-T13173
1mg80.00€5mg167.00€10mg274.00€25mg465.00€50mg655.00€100mg1,017.00€1mL*10mM (DMSO)170.00€Metformin-d6 hydrochloride
CAS:Metformin-d6 hydrochloride (Metformin-d6 hydrochloride) is a deuteride of Metformin, which can be used to study Metformin metabolism in vivo.Formula:C4H12ClN5Purity:98.1%Color and Shape:SolidMolecular weight:171.66XY221
XY221 (Compound 16o) selectively inhibits BRD4 BD2 with an IC50 of 5.8 nM. It demonstrates high selectivity for pan-BD2 and BRD4 BD2 domains, being 667 times more selective than for BRD4 BD1, and 9-32 times more selective than for BRD2/3/T BD2. XY221 can induce apoptosis in MV4-11 cells and exhibits anti-cancer activity.Formula:C32H34FN3O5Molecular weight:559.628Nepodin
CAS:Nepodin exhibits antimalarial, anti-inflammatory, and antidiabetic effects by inhibiting COX and activating AMPK to stimulate GLUT4.Formula:C13H12O3Purity:98.5% - 99.12%Color and Shape:SolidMolecular weight:216.23Ref: TM-TN1100
1mg97.00€5mg235.00€10mg378.00€25mg620.00€50mg868.00€100mg1,169.00€1mL*10mM (DMSO)210.00€GSK621
CAS:GSK621 is a specific and potent AMPK activator.Formula:C26H20ClN3O5Purity:97.02% - 97.05%Color and Shape:SolidMolecular weight:489.91XMD-17-51 Trifluoroacetate
CAS:XMD-17-51 Trifluoroacetate is a pyrimido-diazepinone compound that regulates protein kinases.Formula:C23H25F3N8O3Purity:99.65%Color and Shape:SolidMolecular weight:518.49NUAK1-IN-2
NUAK1-IN-2 (Compound 24) is an inhibitor of NUAK1 with an IC50 of 3.162 nM, as well as an inhibitor of CDK2/4/6. It is applicable in research related to cancer, neurodevelopmental disorders, and Alzheimer's disease.Formula:C24H30N6OColor and Shape:SolidMolecular weight:418.535YM-53601 free base
CAS:YM-53601 free base is an inhibitor of squalene synthetase which suppresses lipogenic biosynthesis and lipid secretion in rodents.Formula:C21H21FN2OPurity:98%Color and Shape:SolidMolecular weight:336.4HTH-02-006
HTH-02-006, a NUAK2 inhibitor (IC50 = 126 nM), decreases phosphorylated MYPT1 levels in HuCCT-1 cells and inhibits YAP-driven cell proliferation, hepatomegaly,Formula:C25H29IN6O3Purity:98%Color and Shape:SoildMolecular weight:588.45ML753286
CAS:ML753286 has high permeability and low to medium clearance in rodent and human liver S9 fractions.Formula:C20H25N3O3Purity:98%Color and Shape:SolidMolecular weight:355.43ARN-3236
CAS:ARN-3236 is an oral active and selective inhibitor of salt-inducible kinase 2 (SIK2), (SIK2, SIK1 and SIK3 with IC50s of <1 nM, 21.63 nM and 6.63 nMFormula:C19H16N2O2SPurity:99.57% - 99.7%Color and Shape:SolidMolecular weight:336.41Ref: TM-T5993
1mg60.00€2mg86.00€5mg124.00€10mg182.00€25mg343.00€50mg427.00€100mg658.00€200mg938.00€500mg1,388.00€1mL*10mM (DMSO)150.00€ZLN024
CAS:ZLN024 is an activator of AMPK allosteric.Formula:C13H13BrN2OSPurity:99.82%Color and Shape:SolidMolecular weight:325.22Ref: TM-T13411
1mg87.00€5mg187.00€10mg284.00€25mg452.00€50mg645.00€100mg867.00€200mg1,130.00€1mL*10mM (DMSO)188.00€Metformin hydrochloride
CAS:Metformin hydrochloride (1,1-Dimethylbiguanide hydrochloride) is an AMPK activator. Metformin is used in type 2 diabetes research. Cost-effective and quality-assured.Formula:C4H12ClN5Purity:97.53% - 99.00%Color and Shape:White Or Almost White Crystals Solid CrystallineMolecular weight:165.63MK-0626
CAS:MK-0626 is an orally available dipeptidyl peptidase IV (DPP-4) inhibitor enhancing AMP, restoring the expression of GLP-1R. promoting neoangiogenesis.Formula:C22H24F2N6O2Purity:100% - 100%Color and Shape:SolidMolecular weight:442.46AMPK activator 4
CAS:Potent, selective AMPK activator 4 enhances glucose tolerance and insulin sensitivity without affecting mitochondrial complex I.Formula:C24H21ClN2O3Purity:100% - 99.75%Color and Shape:SolidMolecular weight:420.89Ref: TM-T62238
1mg90.00€5mg183.00€10mg354.00€25mg595.00€50mg847.00€100mg1,159.00€500mg2,308.00€1mL*10mM (DMSO)215.00€
