mTOR
mTOR inhibitors are compounds that inhibit the activity of Mammalian Target of Rapamycin (mTOR), a central regulator of cell growth, proliferation, metabolism, and survival. The mTOR pathway is frequently altered in cancer and other diseases, making mTOR a critical target for therapeutic intervention. Inhibitors of mTOR are widely used in research related to cancer, aging, and metabolic disorders. At CymitQuimica, we offer a variety of mTOR inhibitors to support your research in signal transduction, oncology, and therapeutic development.
Products of "mTOR"
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Torkinib
CAS:Torkinib (PP 242) (PP 242) is a selective and ATP-competitive mTOR inhibitor (IC50: 8 nM). It also inhibits mTORC1/2 (IC50s: 30/58 nM).Formula:C16H16N6OPurity:99.11%Color and Shape:SolidMolecular weight:308.34Ref: TM-T2414
5mg57.00€10mg74.00€25mg96.00€50mg136.00€100mg227.00€200mg338.00€500mg560.00€1mL*10mM (DMSO)63.00€3BDO
CAS:3BDO is a new mTOR activator. 3BDO inhibits autophagy.Formula:C18H17NO5Purity:96.00%Color and Shape:SolidMolecular weight:327.33Ref: TM-T14033
2mg47.00€5mg69.00€10mg97.00€25mg208.00€50mg331.00€100mg520.00€200mg777.00€500mg1,188.00€1mL*10mM (DMSO)74.00€ETP-45658
CAS:ETP-45658 (ETP45658) is a PI 3-kinase inhibitor (IC50 values are 22, 30, 129 and 710 nM for PI 3-Kα, PI 3-Kδ, PI 3-Kβ and PI 3-Kγ respectively).Formula:C16H17N5O2Purity:99.13%Color and Shape:SolidMolecular weight:311.34Ref: TM-T25399
1mg52.00€5mg111.00€10mg175.00€25mg316.00€50mg512.00€100mg747.00€1mL*10mM (DMSO)124.00€MKC-1
CAS:MKC-1 (Ro-31-7453) is an oral bisindolylmaleimide inhibitor that disrupts tubulin polymerization, potentially halting cancer cell division.Formula:C22H16N4O4Purity:98.38% - 99.46%Color and Shape:SolidMolecular weight:400.39Ref: TM-T9831
1mg57.00€5mg125.00€10mg177.00€25mg309.00€50mg445.00€100mg622.00€500mgTo inquire1mL*10mM (DMSO)134.00€KU-0063794
CAS:KU-0063794 is a potent and highly specific dual-mTOR inhibitor of mTORC1 and mTORC2.Formula:C25H31N5O4Purity:100% - 98.35%Color and Shape:SolidMolecular weight:465.54PI-103
CAS:PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50s: 2/3/3/15/30/23 nM for p110α/β/δ/γ, mTOR, and DNA-PK).Formula:C19H16N4O3Purity:96.59% - 99.3%Color and Shape:SolidMolecular weight:348.36VS-5584
CAS:VS-5584 (SB2343) is a pan-PI3K/mTOR kinase inhibitor.Formula:C17H22N8OPurity:97.82% - 99.54%Color and Shape:SolidMolecular weight:354.41DIM-C-pPhOH
CAS:CDIM8 (DIM-C-pPhOH) opposes NR4A1, halts TGF-β breast cancer migration, induces ROS/ER stress, and mimics Nur77 RNAi in pancreatic cancer.Formula:C23H18N2OPurity:98.61%Color and Shape:SolidMolecular weight:338.4Ref: TM-T4400
2mg44.00€5mg65.00€10mg84.00€25mg153.00€50mg227.00€100mg376.00€200mg495.00€1mL*10mM (DMSO)59.00€Bimiralisib
CAS:Bimiralisib (PI3K-IN-2) is an orally bioavailable pan inhibitor of PI3K and inhibitor of the mTOR, with potential antineoplastic activity.Formula:C17H20F3N7O2Purity:97.58% - 98.92%Color and Shape:SolidMolecular weight:411.38PI3K/mTOR Inhibitor-2
CAS:Potent PI3K/mTOR Inhibitor-2 targets PI3Kα/β/δ/γ & mTOR (IC50: 3.4, 34, 16,1, 4.7 nM); exhibits antitumor effects.Formula:C20H13ClF2N4O4SPurity:96.16%Color and Shape:SolidMolecular weight:478.86Ref: TM-T12459
1mg58.00€5mg145.00€10mg226.00€25mg378.00€50mg540.00€100mg730.00€200mg938.00€1mL*10mM (DMSO)153.00€Dihydromyricetin
CAS:Dihydromyricetin, a flavonoid from Ampelopsis, is an antioxidant that blocks dihydropyrimidinase (IC50: 48 μM) and activates autophagy via mTOR inhibition.Formula:C15H12O8Purity:96.68% - 98.13%Color and Shape:SolidMolecular weight:320.25WAY-600
CAS:WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM; blocks mTORC1/P-S6K(T389) and mTORC2/P-AKT(S473) but not P-AKT(T308).Formula:C28H30N8OPurity:99.63%Color and Shape:SolidMolecular weight:494.59Ref: TM-T6730
1mg38.00€2mg64.00€5mg97.00€10mg140.00€25mg245.00€50mg363.00€100mg507.00€500mgTo inquire1mL*10mM (DMSO)111.00€mTORC1-IN-1
mTORC1-IN-1 (T1), a rapamycin homologue (rapalog) and selective inhibitor of mTORC1, controls cell growth and metabolism, with implications in various diseasesPurity:98%Color and Shape:Odour SolidmTOR inhibitor-12
mTOR inhibitor-12 (Compound 11), a selective, brain-penetrant mTOR inhibitor, exhibits no genotoxicity risk and is utilized in research pertaining to centralFormula:C19H24N6O2SPurity:98%Color and Shape:SolidMolecular weight:400.5D-α-Hydroxyglutaric acid disodium
CAS:D-α-Hydroxyglutaric acid disodium (Disodium (R)-2-Hydroxyglutarate) is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases with Ki of 0.628 mM.Formula:C5H6Na2O5Purity:98%Color and Shape:SolidMolecular weight:192.08Torin 1
CAS:Torin 1 is an effective inhibitor of mTORC1/2 with (IC50: 2 nM/10 nM); has 1000-fold selectivity for mTOR than PI3K.Formula:C35H28F3N5O2Purity:98.3% - 99.38%Color and Shape:SolidMolecular weight:607.62ElteN378
CAS:ElteN378: potently inhibits FKBP12 (Ki=0.5 nM), low weight, similar affinity to Rapamycin.Formula:C23H26N2O3Purity:98.09%Color and Shape:SolidMolecular weight:378.46Ref: TM-T9950
1mg170.00€5mg376.00€10mg557.00€25mg895.00€50mg1,216.00€100mg1,691.00€200mg2,262.00€1mL*10mM (DMSO)329.00€AZD 3147
CAS:AZD 3147 inhibits mTORC1 (40.7 nM), mTORC2 (5.75 nM), and PI3Kα/β/δ/γ (912/5495/9333/6310 nM IC50s).Formula:C24H31N5O4S2Purity:98.34%Color and Shape:SolidMolecular weight:517.66Ref: TM-T36200
1mg97.00€5mg210.00€10mg338.00€25mg582.00€50mg777.00€100mg1,074.00€1mL*10mM (DMSO)273.00€Zotarolimus
CAS:Zotarolimus (ABT-578), an analogue of rapamycin, inhibits FKBP-12 (IC50= 2.8 nM).Formula:C52H79N5O12Purity:95% - ≥98%Color and Shape:SolidMolecular weight:966.21Ref: TM-T6033
1mg66.00€2mg96.00€5mg144.00€10mg225.00€25mg393.00€50mg565.00€100mg818.00€1mL*10mM (DMSO)239.00€mTOR inhibitor-2
CAS:mTOR inhibitor-2 is an inhibitor of selective and oral mTOR (IC50 of 7 nM).Formula:C23H21N7OPurity:98%Color and Shape:SolidMolecular weight:411.46
