mTOR
mTOR inhibitors are compounds that inhibit the activity of Mammalian Target of Rapamycin (mTOR), a central regulator of cell growth, proliferation, metabolism, and survival. The mTOR pathway is frequently altered in cancer and other diseases, making mTOR a critical target for therapeutic intervention. Inhibitors of mTOR are widely used in research related to cancer, aging, and metabolic disorders. At CymitQuimica, we offer a variety of mTOR inhibitors to support your research in signal transduction, oncology, and therapeutic development.
Products of "mTOR"
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MTI-31
CAS:MTI-31 (LXI-15029) is a potent oral mTORC1/2 inhibitor with a Kd of 0.20 nM, >5,000-fold selectivity, and an IC50 of 39 nM.Formula:C26H30N6O3Purity:99.76%Color and Shape:SolidMolecular weight:474.55Daphnetin
CAS:Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),Formula:C9H6O4Purity:97.47% - 99.8%Color and Shape:SolidMolecular weight:178.14TMBIM6 antagonist-1
CAS:TMBIM6 antagonist-1 (BAX-inhibitor-1) is a bax inhibitorFormula:C15H12N2O3Purity:99.26%Color and Shape:SolidMolecular weight:268.27Ref: TM-T8649
1mg93.00€2mg120.00€5mg187.00€10mg315.00€25mg567.00€50mg810.00€100mg1,111.00€500mg2,232.00€1mL*10mM (DMSO)202.00€Rapamycin
CAS:Rapamycin, a macrolide from Streptomyces hygroscopicus, inhibits mTOR (IC50: 0.1 nM) and promotes autophagy with immunosuppressive effects.Formula:C51H79NO13Purity:97.08% - 99.03%Color and Shape:Yellow SolidMolecular weight:914.17Ref: TM-T1537
1g283.00€10mg35.00€25mg48.00€50mg52.00€100mg69.00€200mg106.00€500mg188.00€1mL*10mM (DMSO)50.00€CC214-1
CAS:CC214-1 is an mTOR inhibitor that inhibits protein translation, induces autophagy, and is an in vitro tool compound for exploring the biology of mTOR kinases.Formula:C20H21N7O2Purity:97.87%Color and Shape:SolidMolecular weight:391.43WYE-354
CAS:WYE-354 is a selective mTOR inhibitor (IC50=5 nM), targeting mTORC1/C2 over PI3Kα (>100x) and PI3Kγ (>500x), sparing P-AKT(T308).Formula:C24H29N7O5Purity:97.86% - 99.61%Color and Shape:SolidMolecular weight:495.53Gedatolisib
CAS:Gedatolisib (PF-05212384) is a highly effective dual inhibitor targeting the PI3Kα/γ (IC50: 0.4/5.4 nM)and mTOR (IC50: 1.6 nM) in the PI3K/mTOR signalingFormula:C32H41N9O4Purity:98% - 99.48%Color and Shape:SolidMolecular weight:615.73Omipalisib
CAS:Omipalisib (GSK2126458) is a small-molecule pyridylsulfonamide inhibitor of phosphatidylinositol 3-kinase (PI3K) with potential antineoplastic activity.Formula:C25H17F2N5O3SPurity:98% - 99.8%Color and Shape:SolidMolecular weight:505.5FT-1518
CAS:FT-1518 is an orally available, selective and potent mTORC1 and mTORC2 inhibitor with anticancer and antitumor activity for cancer research.Formula:C20H26N8OPurity:98.34% - 98.80%Color and Shape:SolidMolecular weight:394.47CC-115
CAS:CC-115 is a inhibitor of mTOR/DNA-PK (IC50= 21/ 13 nM).Formula:C16H16N8OPurity:86.79% - 99.22%Color and Shape:SolidMolecular weight:336.35Voxtalisib
CAS:Voxtalisib (XL765) (SAR245409, XL765) is a dual inhibitor of mTOR/PI3K, mostly for p110γ with IC50 of 9 nM; also inhibits DNA-PK and mTOR. Phase 1/2.Formula:C13H14N6OPurity:98.01% - 99.36%Color and Shape:SolidMolecular weight:270.29Ref: TM-T7014
1mg38.00€2mg49.00€5mg79.00€10mg124.00€25mg240.00€50mg384.00€100mg560.00€1mL*10mM (DMSO)79.00€NSC781406
CAS:NSC781406 is a highly effective inhibitor of PI3K and mTOR (IC50: 2 nM for PI3Kα).Formula:C29H27F2N5O5S2Purity:99.58%Color and Shape:SolidMolecular weight:627.68Ref: TM-T16355
2mg42.00€5mg64.00€10mg93.00€25mg168.00€50mg245.00€100mg375.00€200mg533.00€1mL*10mM (DMSO)88.00€Cyclovirobuxine D
CAS:Cyclovirobuxine D (Bebuxine) is extracted from Buxus microphylla.Formula:C26H46N2OPurity:97.78% - 98%Color and Shape:SolidMolecular weight:402.66Rheb inhibitor NR1
CAS:Rheb inhibitor NR1 is a Rheb inhibitor and selective mTORC1 inhibitor that promotes phosphorylation of S473pAKT.Formula:C25H19BrCl2N2O3SPurity:99.72%Color and Shape:SolidMolecular weight:578.3Ref: TM-T16741
1mg92.00€5mg188.00€10mg311.00€25mg628.00€50mg945.00€100mg1,596.00€1mL*10mM (DMSO)47.00€JR-AB2-011
CAS:JR-AB2-011: selective mTORC2 inhibitor, IC50 = 0.36μM, blocks Rictor-mTOR, Ki = 0.19μM, cytotoxic in glioblastoma.Formula:C17H14Cl2FN3OSPurity:98.87%Color and Shape:SolidMolecular weight:398.28Ref: TM-T11728
1mg95.00€5mg202.00€10mg344.00€25mg630.00€50mg945.00€100mg1,264.00€1mL*10mM (DMSO)224.00€Vistusertib
CAS:Vistusertib (AZD2014) is an orally bioavailable inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity.Formula:C25H30N6O3Purity:97.08% - 99.06%Color and Shape:SolidMolecular weight:462.54Ref: TM-T1961
1mg37.00€5mg74.00€10mg117.00€25mg173.00€50mg236.00€100mg378.00€200mg558.00€1mL*10mM (DMSO)84.00€Dactolisib
CAS:Dactolisib (BEZ235) is an orally bioavailable inhibitor of PI3K and mTOR (IC50s: 4 nM/5 nM/7 nM/75 nM, and 20.7 nM for p110α/p110γ/p110δ/p110β and mTOR).Formula:C30H23N5OPurity:97.64% - 99.85%Color and Shape:SolidMolecular weight:469.54Samotolisib
CAS:Samotolisib (LY3023414) inhibits PI3K, DNA-PK, mTOR; tested for solid tumors including breast and colon cancer.Formula:C23H26N4O3Purity:98.41% - 99.69%Color and Shape:SolidMolecular weight:406.48Insecticidal agent 364
CAS:Insecticidal agent 364 is a selective small molecule inhibitor of rapamycin kinase target protein.Formula:C23H18N4O3SPurity:98.24%Color and Shape:SolidMolecular weight:430.48Hederacolchiside A1
CAS:Hederacolchiside A1 exhibits anti-leishmanial and anticancer activities by disrupting cell membranes and inducing apoptosis via the PI3K/Akt/mTOR pathway.Formula:C47H76O16Purity:99.54% - 99.92%Color and Shape:SolidMolecular weight:897.1Ref: TM-T2P2806
1mg48.00€5mg120.00€10mg170.00€25mg283.00€50mg430.00€100mg620.00€1mL*10mM (DMSO)170.00€
