Oligosaccharides

Paromamine is a chemical compound that inhibits protein synthesis by enzymatic inactivation. It has been shown to have a broad spectrum of antibacterial activity against Gram-positive and Gram-negative bacteria. Paromamine also has the ability to inhibit bacterial growth at high salt concentrations, making it an attractive candidate for development as an oral antibiotic drug. Paromamine is synthesized from natural products, such as salicylaldehyde or phenylhydrazine, which are readily available and inexpensive. The reaction mechanism for the formation of paromamine starts with dehydration of the hydroxyl group on the hydrazine to form a carbonyl group. This carbonyl group reacts with sephadex g-100 to form a cyanohydrin. The cyanohydrin reacts with ammonia to form an amide bond between the two nitrogen atoms in the molecule, which forms paromamine.

Blood group antigen with spacer arm

Dermatan sulphate decasaccharide ammonium salt is a synthetic, high purity, complex carbohydrate. The CAS number for this product is 543-58-2. Dermatan sulfate decasaccharide ammonium salt is a complex carbohydrate that has been modified with a fluorine atom at the C1 position of the glucose monosaccharide and an acetyl group at the C4 position of the glucuronic acid monosaccharide. Click chemistry was used to introduce these modifications on the sugar molecule and it has been found to be stable in both acidic and alkaline conditions. This product can be customized for your specific needs, including fluorination, methylation, or glycosylation at any position.

Disialyl-TF is a monoclonal antibody that binds to the CD33 antigen on the surface of all types of cancer cells, including breast cancer cells. Disialyl-TF has been shown to reduce the growth and spread of prostate cancer cells in mice, reducing tumor size and weight. Disialyl-TF is also active against infectious diseases such as HIV, which may be due to its ability to inhibit the expression of glycan receptors. The mechanism by which it works is not yet known. Disialyl-TF has been shown to bind with high affinity to erythrocytes bearing A or B blood group antigens, making it an excellent diagnostic tool for detecting these antigens in patients with acute myeloid leukemia or other cancers.

Biotin-labelled oligosaccharide domain of the monosialylated glycosphingolipid GM2 of a-series. The compound is present on neuronal cells and plays a key role in the regulation of dendritogenesis in cortical pyramidal neurons. In lysosomal storage disorders Tay-Sachs and Sandhoff disease, where hexosaminases A and B are deficient, GM2 ganglioside accumulates in the nervous system. GM2 is also overexpressed in melanomas and other tumours of neuro-ecto origin. Moreover, the sugar moiety of this ganglioside is a receptor allowing viral infection of cells with reovirus and rotavirus.

3,4,2',3',6'-Penta-O-acetylsucrose is a deuterated analog of sucrose. It can be synthesized by reacting sucrose with acetyl chloride in the presence of a base. The transesterification reaction yields the desired product in an overall yield of about 20%. This process is similar to that used for the synthesis of fatty acid esters, but 3,4,2',3',6'-Penta-O-acetylsucrose does not exist in nature and cannot be found as a natural product. The X-ray crystallography studies show that 3,4,2',3',6'-Penta-O-acetylsucrose has a conformation different from that of 6-phosphate sucrose.

3'-Sialyl Lewis X 16-sp - biotin is a modified oligosaccharide that is synthesized by the addition of a sialic acid residue to the terminal position of the carbohydrate. This product has a CAS number and can be custom synthesized to meet specific customer requirements. 3'-Sialyl Lewis X 16-sp - biotin is an important glycosylation site for many proteins, including CD45 and CD47, which are present in erythrocytes and leukocytes respectively. It is also used as an important substrate for methylation reactions due to its susceptibility to S-adenosyl methionine. 3'-Sialyl Lewis X 16-sp - biotin is soluble in water and has a high purity. The structure of this oligosaccharide includes a complex carbohydrate composed of mono-, di-, tri-, tetra-, penta-, hexa-, hepta-, octa-, nona-, deca-sac

Impurity Azithromycin EP Impurity B Applications Azithromycin B (Azithromycin EP Impurity B), is an impurity of Azithromycin (A927000), a semi-synthetic macrolide antibiotic, and related to Erythromycin A. References Langtry, H.D., et al.: Drugs, 56, 273 (1998),

6-O-Sulfated Lewis X is a complex carbohydrate that contains a 6-sulfated Lewis X monosaccharide. It has been synthesized to have a high purity and stability. 6-O-Sulfated Lewis X is soluble in water and can be used as a synthetic building block for the synthesis of saccharides, polysaccharides, and oligosaccharides. The compound has been modified to have fluorination at the C6 position.

Heparin disaccharide IV-A, sodium (HDS) is a complex carbohydrate. It is an oligosaccharide that consists of a number of sugar molecules linked together to form a polysaccharide. HDS can be modified by methylation and glycosylation as well as fluorination and click modification. HDS has high purity and is synthetic.

Lewis X trisaccharide-sp-biotin is a synthetic compound with fluorination, monosaccharide, and oligosaccharide. The sugar is a complex carbohydrate. It is synthesized by glycosylation and polysaccharide modification. The product has high purity and is custom synthesis for research purposes only. This product does not have CAS number because it is a custom synthesis.

Sialic acid-containing glycosphingolipids-important component of neuronal cells

Glycyl-lacto-N-tetraose is an oligosaccharide that is modified with lactose. The structure of this carbohydrate is a glycosyl linkage between two glucose residues, plus a galactose residue at the non-reducing end of the chain. This sugar has been custom synthesized and purified to be free of other carbohydrates or contaminants. Glycyl-lacto-N-tetraose has a CAS number of 55719-02-1 and can be used in many applications including as a pharmaceutical ingredient, food additive, or cosmetic ingredient.

Applications Lewis X and related compounds bind to the selectins and act as anti-inflammatory agents. References Lasky, L.A.: Science, 258, 964 (1992), Mulligan, M.S., et al.: Nature, 364, 149 (1993), Mulligan, M.S., et al.: J. Exp. Med., 178, 623 (1993), Travis, J.: Science, 260, 906 (1993)

Sodium alginate is a biocompatible polymer that is used in the treatment of wastewater. It is a water-soluble substance that forms a viscous solution when dissolved in water. Sodium alginate has been shown to inhibit the growth of bacteria and fungi, as well as to reduce the number of coliforms and other microorganisms in water. The potential for an alginate to be biocompatible depends on its chemical structure, with Laminaria Hyperborea being the most biocompatible. Alginates have been shown to have surface properties that are similar to those of natural tissue, making them useful for wound dressings.