Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
Products of "Cytoskeletal Signaling"
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GRGDSP acetate(91037-75-1 free base)
GRGDSP acetate(91037-75-1 free base) is a synthetic linear RGD peptide and is an integrin inhibitor.Formula:C24H41N9O12Purity:99.77%Color and Shape:SolidMolecular weight:647.64Auristatin E
CAS:Auristatin E, MMAE analog, blocks tubulin polymerisation, has cytotoxic and potent antitumor effects, used in ADCs.Formula:C40H69N5O7Purity:98.81%Color and Shape:SolidMolecular weight:732.01SB-216
CAS:SB-216, a potent anti-cancer compound, inhibits tubulin polymerization and curbs growth in various cancer cells.Formula:C17H18N4O2Purity:100%Color and Shape:SolidMolecular weight:310.35Ref: TM-T60757
1mg54.00€5mg116.00€10mg188.00€25mg331.00€50mg475.00€100mg655.00€1mL*10mM (DMSO)133.00€Dynamin inhibitory peptide, myristoylated acetate
Myristoylated acetate peptide inhibits DynaMin, blocking amphiphysin binding; myristoylated TFA variant hinders endocytosis.Formula:C63H111N19O16Purity:99.42%Color and Shape:SolidMolecular weight:1390.67SC-10
CAS:SC-10 is a direct activator of PKC with potential antiproliferative activity, useful in leukemia research.Formula:C17H22ClNO2SPurity:99.24% - 99.58%Color and Shape:SolidMolecular weight:339.88GRP78-IN-3
CAS:GRP78-IN-3: Potent Hsp70 blocker, selective Grp78 (HSPA5) inhib., IC50 0.59 μM, 7x more vs HspA9, 20x vs HspA2.Formula:C17H18N4O2SPurity:99.11%Color and Shape:SoildMolecular weight:342.42ALK inhibitor 1
CAS:ALK inhibitor 1 is a selective ALK kinase inhibitor.Formula:C23H28BrN7O3SPurity:98.27%Color and Shape:SolidMolecular weight:562.48Ref: TM-T10285
1mg52.00€5mg116.00€10mg170.00€25mg340.00€50mg472.00€100mg645.00€1mL*10mM (DMSO)143.00€KIF18A-IN-3
CAS:KIF18A-IN-3 is a KIF18A inhibitor (IC50=61 nM) that causes significant mitotic arrest and increases the number of mitotic cells in tumor tissues.Formula:C28H38N4O5S2Purity:98.45%Color and Shape:SolidMolecular weight:574.76Combretastatin A-1
CAS:Combretastatin A-1 is a microtubule inhibitor with anti-tumour and can be used to study liver cancer.Formula:C18H20O6Purity:97.49% - 97.49%Color and Shape:SolidMolecular weight:332.35Lifitegrast
CAS:Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist.Formula:C29H24Cl2N2O7SPurity:99.39% - 99.66%Color and Shape:SolidMolecular weight:615.48CGP 53353
CAS:CGP 53353 (DAPH-7) is a PKC inhibitor with inhibitory effects on PKCβII and PKCβI and can be used to study atherosclerosis.Formula:C20H13F2N3O2Purity:98.11%Color and Shape:SolidMolecular weight:365.33PKC-θ inhibitor
CAS:PKC-theta inhibitor is PKC-θinhibitor, with an IC50 of 12 nM.Formula:C20H25F3N6O3Purity:98%Color and Shape:SolidMolecular weight:454.45Ref: TM-T5423
1mg106.00€5mg250.00€10mg329.00€25mg467.00€50mg612.00€100mg944.00€200mg1,264.00€1mL*10mM (DMSO)274.00€Borussertib
CAS:Borussertib is a covalent-allosteric and first-in-class inhibitor of protein kinase Akt(IC50 of 0.8 nM and a Ki of 2.2 nM for Aktwt)Formula:C36H32N6O3Purity:99.00%Color and Shape:SolidMolecular weight:596.68Ref: TM-T8427
1mg133.00€5mg274.00€10mg432.00€25mg715.00€50mg1,008.00€100mg1,359.00€1mL*10mM (DMSO)360.00€FAK-IN-11
FAK-IN-11 (Compound 4l), a FAK inhibitor, specifically targets the ATP binding pocket of FAK to prevent its phosphorylation.Formula:C25H41NO3Purity:98%Color and Shape:SolidMolecular weight:403.6Tirbanibulin Mesylate
CAS:Tirbanibulin Mesylate (KX01 Mesylate) is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).Formula:C27H33N3O6SPurity:99.42%Color and Shape:SolidMolecular weight:527.63Ref: TM-T15675
2mg38.00€5mg56.00€10mg70.00€25mg126.00€50mg243.00€100mg416.00€200mg562.00€1mL*10mM (DMSO)65.00€IPI-493
CAS:IPI-493 is a bioactive chemical.Formula:C28H39N3O8Purity:100%Color and Shape:SolidMolecular weight:545.62WAY-118959-A
CAS:WAY-118959-A is a potential microtubule acetylation inhibitor.Formula:C16H14N4OS2Purity:99.86%Color and Shape:SolidMolecular weight:342.44Ref: TM-T60065
1mg115.00€5mg255.00€10mg375.00€25mg562.00€50mg787.00€100mg1,074.00€200mg1,454.00€1mL*10mM (DMSO)261.00€Sangivamycin
CAS:Sangivamycin (NSC-65346) inhibits PKC (Ki=10μM) and hinders growth in various human cancers.Formula:C12H15N5O5Purity:98.11%Color and Shape:SolidMolecular weight:309.28Ref: TM-T9605
1mg126.00€5mg274.00€10mg416.00€25mg677.00€50mg944.00€100mg1,264.00€1mL*10mM (DMSO)360.00€AKT-IN-2
CAS:AKT-IN-2 is a selective, and orally bioavailable AKT inhibitor (IC50: 5 nM for AKT1).Formula:C25H34F3N7OPurity:98%Color and Shape:SolidMolecular weight:505.583CAI
CAS:3CAI inhibits AKT1/2, reduces mTOR/GSK3β, and triggers apoptosis in colon cancer cells.Formula:C10H8ClNOPurity:98.13%Color and Shape:SolidMolecular weight:193.63Ref: TM-T14034
5mg55.00€10mg77.00€25mg125.00€50mg220.00€100mg330.00€200mg485.00€500mg787.00€1mL*10mM (DMSO)64.00€
