Cytoskeletal Signaling
Cytoskeletal signaling inhibitors are compounds that disrupt the signaling pathways regulating the cytoskeleton, which is crucial for cell shape, motility, division, and intracellular transport. These inhibitors are used to study the dynamics of cytoskeletal proteins, such as actin and tubulin, and their role in processes like cell migration, adhesion, and cancer metastasis. Cytoskeletal signaling inhibitors are valuable in research on cell biology, cancer, and neurobiology. At CymitQuimica, we offer a comprehensive range of high-quality cytoskeletal signaling inhibitors to support your research in these areas.
Products of "Cytoskeletal Signaling"
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ILK-IN-3
CAS:ILK-IN-3 is an inhibitor of integrin linked kinase, and with antitumor activity.Formula:C10H12N6OPurity:99.69%Color and Shape:SolidMolecular weight:232.24(±)-1,2-Diolein
CAS:(±)-1,2-Diolein (1,2-Dioleoyl-rac-glycerol) (1,2-Dioleoyl-rac-glycerol) is a PKC activator. (±)-1,2-Diolein could increases myotubes Ca 2+ influx.Formula:C39H72O5Color and Shape:SolidMolecular weight:620.99Alvespimycin
CAS:Alvespimycin (17-DMAG) is a potent Hsp90 inhibitor with potential anticancer activity, which acts by binding to Hsp90.Formula:C32H48N4O8Purity:100%Color and Shape:SolidMolecular weight:616.75IIQLPEIVVV TFA
IIQLPEIVVV TFA serves as a specific inhibitor targeting the Drp1-Mff interaction. This compound discriminates between physiological and pathological fission, hindering physiological fission which leads to mitochondrial dysfunction. IIQLPEIVVV TFA is also utilized in research related to Huntington's disease.Formula:C54H95N11O14·xC2HF3O2Color and Shape:SolidMolecular weight:1122.40 (free base)Tyrosine kinase-IN-9
CAS:Tyrosine kinase-IN-9 (Compound B) is an inhibitor of c-Abl. It is useful for studying neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.Formula:C20H14ClN3O3Color and Shape:SolidMolecular weight:379.796PF-03814735
CAS:PF-03814735 is a novel, potent and reversible inhibitor of Aurora A/B with IC50of 0.8 nM/5 nM, is less potent to Flt3, FAK, TrkA, and minimally active to Met and FGFR1. Phase 1.Formula:C23H25F3N6O2Purity:98%Color and Shape:SolidMolecular weight:474.48Tirofiban
CAS:Tirofiban (L700462) (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.Formula:C22H36N2O5SPurity:99.87%Color and Shape:SolidMolecular weight:440.63-Hydroxyxanthone
CAS:3-Hydroxyxanthone (3-Hydroxy-xanthen-9-one), a xanthone derivative, exhibits inhibitory effects on NADPH-catalyzed lipid peroxidation in human umbilical veinFormula:C13H8O3Purity:98%Color and Shape:SolidMolecular weight:212.2NPX800
CAS:NPX800 is an inhibitor of heat shock factor 1 (HSF1) and can be used in studies about the treatment of cancer.Formula:C32H32FN5O4Purity:99.26%Color and Shape:SolidMolecular weight:569.63Ref: TM-T9804
1mg96.00€5mg240.00€10mg375.00€25mg627.00€50mg893.00€100mg1,216.00€1mL*10mM (DMSO)300.00€AKT-IN-6
CAS:AKT-IN-6 (INCB-047775) inhibits Akt, a key signaling protein linked to type 2 diabetes and cancer.Formula:C22H20FN5OPurity:98.83%Color and Shape:SolidMolecular weight:389.43Ref: TM-T36310
1mg35.00€5mg74.00€10mg111.00€25mg216.00€50mg354.00€100mg567.00€200mg805.00€1mL*10mM (DMSO)84.00€Radicicol
CAS:Radicicol is an antifungal antibiotic, a inhibitor of Hsp90 & FTO, Anti-malarial , inhibits iNOS gene expression by blocking the p38 kinase and NF-κB/Rel.Formula:C18H17ClO6Purity:98%Color and Shape:White/Yellow PowderMolecular weight:364.78Phorbol 12-myristate 13-acetate
CAS:Phorbol 12-myristate 13-acetate (PMA) belongs to the phorbol ester group of natural products and is an activator of PKC, SphK, and NF-κB.Formula:C36H56O8Purity:100% - 99.5%Color and Shape:White To Off-White SolidMolecular weight:616.83Eg5 Inhibitor V, trans-24
CAS:Eg5 Inhibitor V, trans-24 is a specific and potent Eg5 inhibitor that can be used in cancer research with an IC50 value of 0.65 uM.Formula:C26H21N3O3Purity:97.45%Color and Shape:SolidMolecular weight:423.46Ref: TM-T11155
1mg92.00€5mg205.00€10mg305.00€25mg495.00€50mg677.00€100mg905.00€200mg1,216.00€1mL*10mM (DMSO)227.00€A-286982
CAS:A 286982 blocks the LFA-1 and ICAM-1 integrin-ligand interaction.Formula:C24H27N3O4SPurity:97.81%Color and Shape:SolidMolecular weight:453.55Ref: TM-T21781
1mg35.00€2mg50.00€5mg74.00€10mg107.00€25mg210.00€50mg350.00€100mg522.00€1mL*10mM (DMSO)81.00€BX517
CAS:BX517 (PDK1 inhibitor 2) is a potent and selective inhibitor of PDK1.Formula:C15H14N4O2Purity:99.07%Color and Shape:SolidMolecular weight:282.3DTHIB
CAS:DTHIB robustly inhibits the HSF1 cancer gene signature and prostate cancer cell proliferation.Formula:C13H9ClFN3O3Purity:98.86% - 99.29%Color and Shape:SolidMolecular weight:309.68Ref: TM-T8858
1mg35.00€5mg70.00€10mg104.00€25mg210.00€50mg338.00€100mg540.00€500mg1,130.00€1mL*10mM (DMSO)78.00€AN-019
CAS:AN-019 (NRC-019) is a Bcr-Abl kinase inhibitor with antitumor activity for the study of chronic myelogenous leukemia (CML) and breast cancer.Formula:C25H17F6N5OPurity:98.01%Color and Shape:SolidMolecular weight:517.43ZIP acetate(863987-12-6 free base)
ZIP acetate inhibits PKMζ (protein kinase Mζ), affecting LTP maintenance and spatial memory, with an IC50 of 1-2.5 μM.Formula:C92H158N30O19Purity:94.68%Color and Shape:SolidMolecular weight:1988.43Tilavonemab
CAS:Tilavonemab (ABBV-8E12), a humanized anti-tau antibody, halts tau uptake in neurons and may help with Alzheimer's research.Purity:95% - 95%Color and Shape:LiquidSuprafenacine
CAS:Suprafenacine (N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide) is a cell-permeable microtubule destabilizer that inducesFormula:C16H18N4OPurity:99.72%Color and Shape:SolidMolecular weight:282.34
